Article
Surgery
Rui Sun, Jiawen Yu, Yifan Zhang, Zhika Liang, Xianlin Han
Summary: Through a meta-analysis, it was found that minimally invasive pancreaticoduodenectomy provides similar or improved perioperative, short-term, and long-term oncological outcomes compared to open pancreaticoduodenectomy in patients with pancreatic ductal adenocarcinoma.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Review
Oncology
Bas A. Uijterwijk, Kongyuan Wei, Meidai Kasai, Benedetto Ielpo, Jony van Hilst, Palanivelu Chinnusamy, Daniel H. L. Lemmers, Fernando Burdio, Palanisamy Senthilnathan, Marc G. Besselink, Mohammed Abu Hilal, Renyi Qin
Summary: This study compared the oncological and surgical outcomes of minimally invasive pancreatoduodenectomy (MIPD) and open pancreatoduodenectomy (OPD) in patients with resectable pancreatic ductal adenocarcinoma (PDAC). The results showed that MIPD was non-inferior to OPD in terms of radicality, lymph node yield, major complications, and 90-day mortality. MIPD also had advantages in terms of blood loss, hospital stay, and operation time. These findings suggest that MIPD is a viable alternative to traditional surgery.
Article
Oncology
Emrullah Birgin, Sarah R. Kaslow, Svetlana Hetjens, Camilo Correa-Gallego, Nuh N. Rahbari
Summary: In patients with HCC, minimally invasive liver resection is associated with similar overall survival but improved short-term postoperative outcomes compared to traditional open liver resection. However, there is a higher rate of positive margins after MILR, which requires further investigation, and surgical procedures at academic institutions may help prevent these adverse outcomes.
Article
Gastroenterology & Hepatology
Wei Zhang, Jianwei Zhang, Xu Che
Summary: This study compared the short-term and long-term outcomes of minimally invasive surgery (MIS) with open pancreas surgery (OPS) for pancreatic neuroendocrine neoplasms (pNENs). The results showed that MIS had lower estimated blood loss, shorter postoperative hospitalization time, lower recurrence rate, and higher long-term survival rate compared to OPS. However, there were no significant differences between the two groups in terms of operative time and postoperative complications. Therefore, MIS may be a preferable treatment option for pNENs.
Article
Oncology
Glauco Baiocchi, Reitan Ribeiro, Ricardo Dos Reis, Deraldo Fernando Falcao, Andre Lopes, Ronaldo Lucio Rangel Costa, Gabriel Lowndes Souza Pinto, Marcelo Vieira, Lillian Yuri Kumagai, Carlos Chaves Faloppa, Henrique Mantoan, Levon Badiglian-Filho, Audrey Tieko Tsunoda, Tariane Friedrich Foiato, Carlos Eduardo Mattos Cunha Andrade, Leonardo Oliveira Palmeira, Bruna Tirapelli Goncalves, Paulo Henrique Zanvettor
Summary: The study found similar survival outcomes between minimally invasive and open radical hysterectomy for early stage cervical cancer patients in a Brazilian cohort.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Review
Endocrinology & Metabolism
Abdallah Al-Salameh, Guillaume Cadiot, Alain Calender, Pierre Goudet, Philippe Chanson
Summary: Multiple endocrine neoplasia type 1 (MEN1) is a rare syndrome characterized by the co-occurrence of primary hyperparathyroidism, duodenopancreatic neuroendocrine tumours (NETs) and/or pituitary adenomas. Patients with MEN1 should undergo tailored biochemical and imaging screening. Knowledge about the clinical phenotype of these tumours has progressed over the past 10 years, particularly in France and the Netherlands.
NATURE REVIEWS ENDOCRINOLOGY
(2021)
Review
Surgery
Suhyun Lee, Chris Varghese, Matthew Fung, Bijendra Patel, Sanjay Pandanaboyana, Bobby V. M. Dasari
Summary: The systematic review evaluates the cost-effectiveness of minimally invasive surgery (MIS) and open distal pancreatectomy and pancreaticoduodenectomy. The study includes 22 studies and 152,651 patients, and finds that MIS has higher costs for surgical procedure, equipment, and operating room occupation, but lower overall index hospitalisation costs.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
Article
Surgery
Lianne Scholten, Sjors Klompmaker, Jony Van Hilst, Mario M. Annecchiarico, Gianpaolo Balzano, Riccardo Casadei, Jean-Michel Fabre, Massimo Falconi, Giovanni Ferrari, Mustafa Kerem, Igor E. Khatkov, Carlo Lombardo, Alberto Manzoni, Michele Mazzola, Niccolo Napoli, Edoardo E. Rosso, Pavel Tyutyunnik, Ulrich F. Wellner, David Fuks, Fernando Burdio, Tobias Keck, Mohammed Abu Hilal, Marc G. Besselink, Ugo Boggi
Summary: This multicenter retrospective study suggests that minimally invasive total pancreatectomy may be a valuable alternative to open total pancreatectomy, given the associated lower rate of major morbidity.
Article
Oncology
Thomas L. Sutton, Rodney F. Pommier, Skye C. Mayo, Erin W. Gilbert, Pavlos Papavasiliou, Michele Babicky, Jon Gerry, Brett C. Sheppard, Patrick J. Worth
Summary: This study compared the outcomes of open surgeries and minimally invasive surgeries for pancreatic neuroendocrine tumors (PNETs). It concluded that patients receiving minimally invasive surgery had similar survival rates and disease progression rates as patients receiving open surgery, with no significant differences in complications. Therefore, the routine use of minimally invasive surgery techniques for selected PNET patients is recommended.
Review
Gastroenterology & Hepatology
Raffaello Roesel, Lorenzo Bernardi, Marco A. Bonino, Sotirios G. Popeskou, Fabio Garofalo, Alessandra Cristaudi
Summary: This study aimed to provide current evidence on minimally invasive pancreatic enucleations and explore the advantages of this approach over traditional surgery. A total of 20 studies involving 552 patients were included, and the results showed that minimally invasive surgery has comparable short-term clinical outcomes to open surgery.
Review
Biochemistry & Molecular Biology
Francesca Marini, Francesca Giusti, Francesco Tonelli, Maria Luisa Brandi
Summary: Pancreatic neuroendocrine tumors (pNETs) are a rare group of cancers, accounting for about 1-2% of all pancreatic neoplasms, with some arising in patients with endocrine tumor syndromes such as Multiple Endocrine Neoplasia type 1 (MEN1). MEN1-related pNETs present challenges in treatment due to their unique characteristics and the need for extensive surgery. Epigenetic-based therapies aiming to correct DNA methylation and histone modifications may offer a potential therapeutic strategy for MEN1 pNETs resistant to standard treatments.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Surgery
Matthias Pfister, Pascal Probst, Philip C. Mueller, Pia Antony, Rosa Klotz, Eva Kalkum, Daniela Merz, Pietro Renzulli, Fabian Hauswirth, Markus K. Muller
Summary: This systematic review and meta-analysis provides level 1 evidence for the comparison between minimally invasive and open pancreatic surgery. Minimally invasive surgery appears to be feasible and safe, with comparable morbidity rates and reduced length of hospital stay and intraoperative blood loss. However, longer duration of surgery was observed in partial pancreatoduodenectomy using minimally invasive approach.
Article
Surgery
Frederick Huynh, Charles Jimenez Cruz, Ho Kyoung Hwang, Woo Jung Lee, Chang Moo Kang
Summary: The study compared the surgical outcomes of open central pancreatectomies (O-CP) and minimally invasive central pancreatectomies (MI-CP), finding that MI-CP had advantages in terms of operating time and postoperative blood loss, and was comparable to O-CP in terms of perioperative complications.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Medicine, General & Internal
Halit Topal, Raymond Aerts, Annouschka Laenen, Andre Collignon, Joris Jaekers, Joachim Geers, Baki Topal
Summary: A comparative study of 396 patients with pancreatic adenocarcinoma found that minimally invasive pancreatic surgery (MIPS) was associated with better long-term overall survival (OS) and disease-free survival (DFS) compared to open pancreatic surgery (OPS).
Article
Oncology
Yan Zheng, Yin Li, Xianben Liu, Haibo Sun, Sining Shen, Yufeng Ba, Zongfei Wang, Shilei Liu, Wenqun Xing
Summary: This study found that McKeown-MIE was associated with better long-term survival than McKeown-OE for resectable EC patients. It had shorter operative time, postoperative stay, and comparable mortality rates, but significantly higher 60-month survival.
ANNALS OF SURGICAL ONCOLOGY
(2021)