期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 22, 期 14, 页码 3821-3828出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v22.i14.3821
关键词
Pancreaticoduodenectomy; Postoperative complications; Enteral nutrition; Parenteral nutrition; Delayed gastric emptying
资金
- National Natural Science Foundation [81372582]
- New-Star Young Scientists Program of Shaanxi Province [2014kjxx-30]
- Fundamental Research Funds for the Central Universities
AIM: To analyze and compare postoperative morbidity between patients receiving total parenteral nutrition (TPN) and early enteral nutrition supplemented with parenteral nutrition (EEN + PN). METHODS: three hundred and forty patients receiving pancreaticoduodenectomy (PD) from 2009 to 2013 at our center were enrolled retrospectively. Patients were divided into two groups depending on postoperative nutrition support scheme: an EEN + PN group (n = 87) and a TPN group (n = 253). Demographic characteristics, comorbidities, preoperative biochemical parameters, pathological diagnosis, intraoperative information, and postoperative complications of the two groups were analyzed. RESULTS: The two groups did not differ in demographic characteristics, preoperative comorbidities, preoperative biochemical parameters or pathological findings (p > 0.05 for all). However, patients with EEN + PN following PD had a higher incidence of delayed gastric emptying (16.1% vs 6.7%, p = 0.016), pulmonary infection (10.3% vs 3.6%, p = 0.024), and probably intraperitoneal infection (18.4% vs 10.3%, p = 0.059), which might account for their longer nasogastric tube retention time (9 d vs 5 d, p = 0.006), postoperative hospital stay (25 d vs 20 d, p = 0.055) and higher hospitalization expenses (USD10397 vs USD8663.9, p = 0.008), compared to those with TPN. CONCLUSION: Our study suggests that TPN might be safe and sufficient for patient recovery after PD. Postoperative EEN should only be performed scrupulously and selectively.
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