Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injury

Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice

(2016) Colin T. Shearn et al.   Redox Biology

Transient Receptor Potential Vanilloid 1 Gene Deficiency Ameliorates Hepatic Injury in a Mouse Model of Chronic Binge Alcohol-Induced Alcoholic Liver Disease

(2015) Huilin Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Increased 4-hydroxynonenal protein adducts in male GSTA4–4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease

(2015) Martin J. J. Ronis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Acetaldehyde accelerates HCV-induced impairment of innate immunity by suppressing methylation reactions in liver cells

(2015) Murali Ganesan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Isoaspartate, carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury

(2015) Wayne G. Carter et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosis

(2015) C.T. Shearn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice

(2015) Peng Chen et al.   GASTROENTEROLOGY

Methionine adenosyltransferase α2 sumoylation positively regulate Bcl-2 expression in human colon and liver cancer cells

(2015) Maria Lauda Tomasi et al.   Oncotarget

Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidney

(2015) Peter S. Harris et al.   Redox Biology

Antiviral treatment of hepatitis C

(2014) E. R. Feeney et al.   BMJ-British Medical Journal

Alcohol Consumption Decreases Rat Hepatic Creatine Biosynthesis Via Altered Guanidinoacetate Methyltransferase Activity

(2013) Kusum K. Kharbanda et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Dietary fat sources differentially modulate intestinal barrier and hepatic inflammation in alcohol-induced liver injury in rats

(2013) Wei Zhong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interferon alpha induced intrahepatic pSTAT1 inversely correlate with serum HCV RNA levels in chronic HCV infection

(2013) Feyza Gunduz et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice

(2013) Maria Lauda Tomasi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alcoholic liver disease: Pathogenesis, management, and novel targets for therapy

(2013) Eric S Orman et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Preservation of Hepatocyte Nuclear Factor-4α Contributes to the Beneficial Effect of Dietary Medium Chain Triglyceride on Alcohol-Induced Hepatic Lipid Dyshomeostasis in Rats

(2012) Qiong Li et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Protein Carbonylation in a Murine Model for Early Alcoholic Liver Disease

(2012) James J. Galligan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Alcohol Metabolism

(2012) Arthur I. Cederbaum   Clinics in Liver Disease

Methionine metabolic pathway in alcoholic liver injury

(2012) Kusum K. Kharbanda   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

S-adenosyl methionine regulates ubiquitin-conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers

(2012) Maria Lauda Tomasi et al.   HEPATOLOGY

Mechanism and Significance of Changes in Glutamate-Cysteine Ligase Expression during Hepatic Fibrogenesis

(2012) Komal Ramani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease

(2012) Tung-Ming Leung et al.   JOURNAL OF HEPATOLOGY

Mitochondrial Acetylome Analysis in a Mouse Model of Alcohol-Induced Liver Injury Utilizing SIRT3 Knockout Mice

(2012) Kristofer S. Fritz et al.   JOURNAL OF PROTEOME RESEARCH

Lipidic last breath of life in patients with alcoholic liver disease

(2012) Joanna Raszeja-Wyszomirska et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation

(2012) Kai Connie Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Acute Alcohol-Induced Liver Injury

(2012) Veronica L. Massey et al.   Frontiers in Physiology

The Type of Dietary Fat Modulates Intestinal Tight Junction Integrity, Gut Permeability, and Hepatic Toll-Like Receptor Expression in a Mouse Model of Alcoholic Liver Disease

(2011) Irina A. Kirpich et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

Detection, Quantification, and Microlocalisation of Targets of Pesticides Using Microchannel Plate Autoradiographic Imagers

(2011) Mabruka H. Tarhoni et al.   MOLECULES

Alcoholic liver disease: pathogenesis and new targets for therapy

(2011) José Altamirano et al.   Nature Reviews Gastroenterology & Hepatology

Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: Mechanisms and pathophysiological role

(2011) J. Aubert et al.   Clinics and Research in Hepatology and Gastroenterology

Chronic Alcohol Exposure Increases Circulating Bioactive Oxidized Phospholipids

(2010) Lili Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents

(2010) Amol M. Patwardhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic Ethanol Consumption Induces Global Hepatic Protein Hyperacetylation

(2009) Blythe D. Shepard et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Mass Spectrometric Characterization of Protein Modification by the Products of Nonenzymatic Oxidation of Linoleic Acid

(2009) Xiaochun Zhu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Liver Proteome Analysis in a Rodent Model of Alcoholic Steatosis

(2009) Billy W. Newton et al.   JOURNAL OF PROTEOME RESEARCH

The molecular basis of the host response to lipopolysaccharide

(2009) Clare E. Bryant et al.   NATURE REVIEWS MICROBIOLOGY

Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

(2009) A. M. Patwardhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ethanol intoxication increases hepatic N-lysyl protein acetylation

(2008) Matthew J. Picklo   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Formation, Localization, and Repair ofl-Isoaspartyl Sites in Histones H2A and H2B in Nucleosomes from Rat Liver and Chicken Erythrocytes†

(2008) Wayne G. Carter et al.   BIOCHEMISTRY