Article
Environmental Sciences
Kawaljeet Kaur, Sagar Reddy, Pramod Barathe, Uttara Oak, Varsha Shriram, Sanjay S. Kharat, M. Govarthanan, Vinay Kumar
Summary: The widespread use of microplastics and antibiotics in the environment, particularly in water bodies, is causing contamination and leading to antimicrobial resistance (AMR) in bacteria. Microplastics serve as hosts and carriers of microbial pathogens and their associated AMR genes, forming synthetic plastispheres and facilitating the transfer of genes. Microplastic-associated AMR is a growing threat to human health and healthcare and requires effective management. This review discusses the prevalence of microplastics in water environments, their role in AMR, and potential strategies for addressing this issue.
Article
Biochemistry & Molecular Biology
Adriana Cabal, Gerhard Rab, Beatriz Daza-Prieto, Anna Stoeger, Nadine Peischl, Ali Chakeri, Solveig Solverod Mo, Harald Bock, Klemens Fuchs, Jasmin Sucher, Krista Rathammer, Petra Hasenberger, Silke Stadtbauer, Manuela Canica, Peter Strauss, Franz Allerberger, Markus Wogerbauer, Werner Ruppitsch
Summary: Antimicrobial resistance (AMR) is a public health issue caused by the misuse of antibiotics in both human and veterinary medicine. In a laboratory in Austria, various bacterial species were sampled from different compartments, and their antimicrobial resistance genes were detected. Early detection of antimicrobial resistance can help prevent its spread along the food/feed chain.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Environmental Sciences
Weitao Wang, You Weng, Ting Luo, Qiang Wang, Guiling Yang, Yuanxiang Jin
Summary: Antimicrobial contamination and resistance is a global problem caused by the release of residual antimicrobials into the environment from medical and animal husbandry activities. The role of environmental factors in antimicrobial contamination and resistance is often underestimated, leading to ecological harm and the spread of resistance. This review explores the fate of antimicrobials and resistance in the environment, their impact on ecology and human health, and highlights environmental factors that exacerbate contamination and resistance. Removing antimicrobials and resistance genes in a timely manner will be essential for addressing antimicrobial contamination and resistance.
Article
Engineering, Environmental
Lu-Xi He, Liang-Ying He, Fang-Zhou Gao, Min Zhang, Jun Chen, Wei-Li Jia, Pu Ye, Yu-Wei Jia, Bai Hong, Si-Si Liu, You-Sheng Liu, Jian-Liang Zhao, Guang-Guo Ying
Summary: Antibiotics are being used extensively in mariculture, leading to the spread of antibiotic resistance in the marine environment. This study investigated the pollution, distribution, and characteristics of antibiotics, antibiotic resistance genes (ARGs), and microbiomes. The findings revealed the presence of 20 antibiotics in Chinese coastal areas, with higher concentrations and more types of antibiotics detected in mariculture sites compared to control sites. Certain antibiotics, such as enrofloxacin, ciprofloxacin, and sulfadiazine, posed a high risk of resistance selection. The study also highlighted the presence of high-risk ARGs in certain bacterial phyla, suggesting a potential threat to human health.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Andrea Laconi, Roberta Tolosi, Lapo Mughini-Gras, Matteo Mazzucato, Nicola Ferre, Lisa Carraro, Barbara Cardazzo, Francesca Capolongo, Roberta Merlanti, Alessandra Piccirillo
Summary: The use of antimicrobials in agriculture, veterinary medicine, and human healthcare has led to the emergence and spread of antimicrobial resistance (AMR) in environmental microbiota. This study aimed to investigate the prevalence and origin of AMR genes (ARGs) in beehive products, such as honey and pollen. The results showed that honey and pollen samples contained ARGs conferring resistance to multiple classes of antimicrobials. The findings suggest that honey and pollen can serve as bioindicators of AMR environmental contamination and that the antimicrobial resistance in these products might originate from the honeybee's foraging environment.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Ian Martin, Alwyn Hart
Summary: Antifungals such as ketoconazole and miconazole were detected in biosolids from ten sites in England and one in Wales, indicating that biosolids can be a viable pathway for these drugs to reach soil. The study also found the presence of prescription-only medications itraconazole and posaconazole, raising concerns about the potential for clinical resistance in patients. The levels of itraconazole in biosolids were alarmingly high, surpassing the Predicted No Effect Concentration for resistance selection in soil.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Infectious Diseases
Ayako Wendy Fujita, Kaitlyn Werner, Jesse T. Jacob, Rea Tschopp, Gezahegne Mamo, Adane Mihret, Alemseged Abdissa, Russell Kempker, Paulina A. Rebolledo
Summary: This study reviewed the prevalence of antimicrobial resistance (AMR) in humans, animals, and the environment in Ethiopia from 2016 to 2020. High prevalence of AMR was observed, with Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus being the most common bacteria in humans. Gram-negative organisms showed high rates of resistance to third-generation cephalosporins, fluoroquinolones, and sulfamethoxazole-trimethoprim. Humans had the highest resistance rates, followed by environmental isolates.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Review
Environmental Sciences
Saurav Kumar, Tapas Paul, S. P. Shukla, Kundan Kumar, Sutanu Karmakar, Kuntal Krishna Bera, Chandra Bhushan Kumar
Summary: Triclosan (TCS), an emergent pollutant, is raising global concern due to its toxic effects on organisms and aquatic ecosystems. Thorough research on identifying potential biomarkers for assessing chronic effects of TCS is crucial for addressing ecological impacts and monitoring in the future. Subcellular biomarkers such as oxidative stress, lipid peroxidation, neurotoxicity, and metabolic enzymes can be used to evaluate the cytotoxic effect of TCS in future investigations.
ENVIRONMENTAL POLLUTION
(2021)
Article
Microbiology
Xiaoyang Jiao, Wenyan Guo, Xin Li, Fen Yao, Mi Zeng, Yumeng Yuan, Xiaoling Guo, Meimei Wang, Qing Dong Xie, Leshan Cai, Feiyuan Yu, Pen Yu, Yong Xia
Summary: The presence of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in dental waste water (DWW) contributes to the spread of antimicrobial resistance (AMR) and poses a potential threat to environmental health. Treatment methods such as filter membranes and ozone are only partially effective in removing ARGs and MGEs from DWW.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Environmental Sciences
Wenguang Xiong, Jintao Yang, Jiaxiong Zeng, Danyu Xiao, Cuihong Tong, Zhenling Zeng
Summary: Duck farms are important sources of antimicrobial resistance genes (ARGs) that spread to humans and the environment. This study explored the distribution characteristics and potential transmission mechanisms of ARGs in ducks, farm workers, and the environment. The findings suggest that duck manure is a potential hotspot source of ARGs, including tet(X) variants, which spread to the surrounding environment and workers via mobile genetic elements (MGEs). These results help optimize antimicrobial strategies and deepen our understanding of ARG spread in duck farms.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Agriculture, Dairy & Animal Science
M. Suman Kumar, T. P. Ramees, H. Dhanze, S. Gupta, Z. B. Dubal, A. Kumar
Summary: The presence of antimicrobial resistant Campylobacter spp. in broiler chicken samples and slaughter house settings presents a significant threat to public health, especially with the high occurrence of multidrug resistance. This calls for the prudent use of antimicrobials.
ANIMAL BIOTECHNOLOGY
(2023)
Article
Veterinary Sciences
Cui-Yi Liao, Balamuralikrishnan Balasubramanian, Jin-Ju Peng, Song-Ruo Tao, Wen-Chao Liu, Yi Ma
Summary: The study evaluated antimicrobial resistance of Escherichia coli in aquaculture farms of Zhanjiang, China by analyzing 90 strains isolated from water, soil, and sediment samples. These strains showed high resistance to multiple antimicrobial drugs and carried various resistance genes. Strengthening rational use of antimicrobial drugs, especially amide alcohol drugs, is crucial to controlling antimicrobial resistance in Zhanjiang's aquaculture industry.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Food Science & Technology
A. Hernandez-Ledesma, E. Cabrera-Diaz, S. M. Arvizu-Medrano, A. Gomez-Baltazar, M. Hernandez-Iturriaga, A. Godinez-Oviedo
Summary: This study evaluated the association among antimicrobial resistance, virulence, and origin of circulating Salmonella enterica strains in Mexico. The results showed that certain specific antimicrobial resistance and virulence genes were related to the origin of the strains. Animal-origin food strains showed similar genotypic and phenotypic characteristics to human isolates, suggesting that they are the main cause of human infections. These findings can be used to improve risk estimation assessments in national food safety surveillance programs.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2023)
Article
Microbiology
Muhammad Shoaib, Zhoulin He, Xiang Geng, Minjia Tang, Ruochen Hao, Shengyi Wang, Ruofeng Shang, Xuehong Wang, Hongjuan Zhang, Wanxia Pu
Summary: E. coli strains were isolated from a dairy farm environment in Xinjiang, China, and their epidemiological characteristics, antimicrobial resistance, virulence-associated genes, and phylogenetic relationship were investigated. The majority of the E. coli strains showed resistance to sulfamethoxazole/trimethoprim and cefotaxime. The strains carried widely distributed antibiotic resistance genes and virulence-associated genes, posing a potential threat to humans through contaminated milk and meat, surface water, and agricultural crops.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Cecilia Salazar, Matias Gimenez, Nadia Riera, Andres Parada, Josefina Puig, Antonio Galiana, Fabio Grill, Mariela Vieytes, Christopher E. Mason, Veronica Antelo, Bruno D'Alessandro, Jimena Risso, Gregorio Iraola
Summary: This study extensively examines the microbial communities in urban waters and their correlation with human-derived bacteria and antimicrobial resistance. The findings reveal the impact of hospital outbreaks on the urban environment and highlight the potential of urban metagenomics and outbreak genomic surveillance in infection control, antibiotic stewardship, and pathogen epidemiology.
