Effect of Febuxostat, a Xanthine Oxidase Inhibitor, on Cardiovascular Risk in Hyperuricemic Patients with Hypertension: A Prospective, Open-label, Pilot Study

Elevated Serum Uric Acid is Associated With Angiotensinogen in Obese Patients With Untreated Hypertension

(2014) Junxia Zhang et al.   Journal of Clinical Hypertension

The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: study protocol for a multicenter randomized controlled study

(2014) Tatsuo Hosoya et al.   Trials

Efficacy and Tolerability of Febuxostat in Hyperuricemic Patients With or Without Gout: A Systematic Review and Meta-Analysis

(2013) Peng Ye et al.   CLINICAL THERAPEUTICS

Potential Role of Uric Acid in Metabolic Syndrome, Hypertension, Kidney Injury, and Cardiovascular Diseases: Is It Time for Reappraisal?

(2013) Zohreh Soltani et al.   CURRENT HYPERTENSION REPORTS

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

(2013) Ikuko Maejima et al.   EMBO JOURNAL

Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance

(2013) Annayya R. Aroor et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Crystalline Nephropathies

(2012) Leal C. Herlitz et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Renal Function in Gout

(2012) Andrew Whelton et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Febuxostat inhibition of endothelial-bound XO: Implications for targeting vascular ROS production

(2011) Umair Z. Malik et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk

(2010) M. Goicoechea et al.   Clinical Journal of the American Society of Nephrology

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial

(2010) Awsan Noman et al.   LANCET

Complementary effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in slowing the progression of chronic kidney disease

(2009) Elizabeth Ripley   AMERICAN HEART JOURNAL

Revised Equations for Estimated GFR From Serum Creatinine in Japan

(2009) Seiichi Matsuo et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Hyperuricemia and Incident Heart Failure

(2009) Eswar Krishnan   Circulation-Heart Failure

Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients

(2009) Toshio Ogihara et al.   HYPERTENSION RESEARCH

Effect of Allopurinol on Blood Pressure of Adolescents With Newly Diagnosed Essential Hypertension

(2008) Daniel I. Feig et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Uric Acid and Cardiovascular Risk

(2008) Daniel I. Feig et al.   NEW ENGLAND JOURNAL OF MEDICINE