Article
Pediatrics
Farzaneh Mardali, Mahdyieh Naziri, Mohammad Hassan Sohouli, Somaye Fatahi, Fatemeh Sadat Hosseini-Baharanchi, Mihnea-Alexandru Gaman, Farzad Shidfar
Summary: This study compared the predictive ability of different anthropometric indices for overweight and obesity in Iranian preschool children. The results suggest that tri-ponderal mass index (TMI) and neck circumference (NC) may be useful in predicting general and central obesity in this population.
Article
Environmental Sciences
Ya Mei Li, Zhi Yong Zou, Ying Hua Ma, Jia You Luo, Jin Jing, Xin Zhang, Chun Yan Luo, Hong Wang, Hai Ping Zhao, De Hong Pan, Mi Yang Luo
Summary: The study found that anthropometric indices have good predictive performance for metabolic syndrome in Chinese adolescents, but perform poorly in overweight and obese participants. Waist circumference showed relatively better performance in all subgroup analyses.
BIOMEDICAL AND ENVIRONMENTAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Jun Gyo Gwon, Jimi Choi, Cheol Woong Jung, Chang Hun Lee, Se Won Oh, Sang-Kyung Jo, Won Yong Cho, Jae Berm Park, Kyu Ha Huh, Han Ro, Seungyeup Han, Jang-Hee Cho, Sik Lee, Jaeseok Yang, Myung-Gyu Kim
Summary: This study found that an increase in waist to hip ratio (WHR) among kidney transplant recipients can increase the risk of developing cardiovascular diseases, especially in older age and diabetes patients. However, baseline body mass index (BMI) did not predict the incidence of new onset CVD in these patients. Strategies to prevent metabolic burden post-transplantation may improve cardiovascular outcomes and patient survival.
SCIENTIFIC REPORTS
(2021)
Article
Health Care Sciences & Services
Feng-Ching Shen, Yi-Wen Chiu, Mei-Chuan Kuo, Ming-Yen Lin, Jia-Jung Lee, Shang-Jyh Hwang, Jer-Ming Chang, Chi-Chih Hung, Hung-Chun Chen
Summary: The study found the obesity paradox in patients with chronic kidney disease (CKD), where high BMI is associated with low all-cause mortality risk. Central obesity may have better prognostic value than BMI for all-cause mortality, and low WHR or low BMI and high WHR, rather than high BMI, are associated with all-cause mortality in advanced CKD.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Fatemeh Moosaie, Seyede Marzie Fatemi Abhari, Niloofar Deravi, Arman Karimi Behnagh, Sadaf Esteghamati, Fatemeh Dehghani Firouzabadi, Soghra Rabizadeh, Manouchehr Nakhjavani, Alireza Esteghamati
Summary: This study followed up on 1,685 normotensive patients with type 2 diabetes and found that WHtR was a more accurate tool for predicting hypertension compared to WHR and BMI in these patients.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Endocrinology & Metabolism
Jiang-Feng Ke, Jun-Wei Wang, Jun-Xi Lu, Zhi-Hui Zhang, Yun Liu, Lian-Xi Li
Summary: Comparing the associations between four anthropometric indices and cardio-cerebrovascular events in Chinese T2DM patients, it was found that waist-to-height ratio (WHtR) had a stronger association and may be a better indicator for evaluating cardiovascular risks in this population.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2022)
Article
Medicine, Research & Experimental
Eduardo Rangel-Baltazar, Sonia Rodriguez-Ramirez, Lucia Cuevas-Nasu, Teresa Shamah-Levy, Ignacio Mendez-Gomez-Humaran, Juan A. Rivera
Summary: The optimal waist-to-height ratio (WHtR) cut-off points for predicting cardiovascular risk (CVR) in Mexican adults vary by sex and height, with higher cut-off points for women than for men, and for individuals with short stature.
ARCHIVES OF MEDICAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Marta Borges-Canha, Joao Sergio Neves, Maria Manuel Silva, Fernando Mendonca, Telma Moreno, Sara Ribeiro, Joao Correa, Catarina Vale, Juliana Goncalves, Helena Urbano Ferreira, Sara Gil-Santos, Vanessa Guerreiro, Ana Sande, Selma B. Souto, Jorge Pedro, Paula Freitas, Davide Carvalho
Summary: Non-alcoholic fatty liver disease is associated with other metabolic disorders and inflammation. Body fat content, especially abdominal fat, is linked to negative cardiometabolic outcomes.
Article
Medicine, General & Internal
Xin'nan Zong, Roya Kelishadi, Young Mi Hong, Peter Schwandt, Tandi E. Matsha, Jose G. Mill, Peter H. Whincup, Lucia Pacifico, Abel Lopez-Bermejo, Carmelo Antonio Caserta, Carla Campos Muniz Medeiros, Anastasios Kollias, Mostafa Qorbani, Fariborz Sharifian Jazi, Gerda-Maria Haas, Rafael de Oliveira Alvim, Divanei Zaniqueli, Claudio Chiesa, Judit Bassols, Elisabetta Lucia Romeo, Danielle Franklin de Carvalho, Monica Oliveira da Silva Simoes, George S. Stergiou, Evangelos Grammatikos, Min Zhao, Costan G. Magnussen, Bo Xi
Summary: This study aimed to determine the optimal waist-to-height ratio (WHtR) cutoffs in children and adolescents with increased cardiometabolic risk across different countries worldwide. The results showed that the optimal cutoff values varied between the 75th and 95th percentiles across the ten countries, with a trend of lower cutoffs in Asian, African, and South American youths compared to European and US youths.
Article
Multidisciplinary Sciences
Pei-Ju Liao, Yu-Ching Lin, Ming-Kuo Ting, I. -Wen Wu, Shuo-Wei Chen, Ning-I. Yang, Kuang-Hung Hsu
Summary: This study found an association between sarcopenia-associated body measurements and chronic diseases, with decreased waist width, upper left arm circumference, and left thigh circumference being significantly related to sarcopenia. The adverse body measure score (ABMS), derived from combining these measurements, was able to predict the risk of hypertension, type 2 diabetes, heart diseases, and nephrotic syndrome. Chronic diseases showed a stronger association with ABMS than with sarcopenia-related body measurements alone, and a higher ABMS was found to significantly predict chronic diseases such as hypertension, T2DM, heart disease, and nephrotic syndrome.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
Xiao-Cong Liu, Ying-Shan Liu, Hai-Xia Guan, Ying-Qing Feng, Jian Kuang
Summary: This study evaluated the performance of new anthropometric measures and a combination of anthropometric measures for identifying diabetes. The results showed that waist-to-height ratio (WtHR) and conicity index (CI) had the best ability to identify diabetes in the noninstitutionalized population.
JOURNAL OF DIABETES
(2022)
Article
Nutrition & Dietetics
Shih-Yao Su, Tsung-Han Lin, Yi-Hsueh Liu, Pei-Yu Wu, Jiun-Chi Huang, Ho-Ming Su, Szu-Chia Chen
Summary: Hyperuricemia is associated with diabetes, gout, kidney, and cardiovascular diseases, but there is limited data on sex differences in this association. This study aimed to explore sex differences in the correlations between obesity indices and hyperuricemia in Taiwan. The results showed that obesity-related indices were significantly associated with hyperuricemia in both men and women, with stronger associations found in women. This large Taiwanese study provides important insights into the relationship between obesity and hyperuricemia, highlighting the need for considering sex differences in these associations.
Article
Endocrinology & Metabolism
Shuxian Wang, Baorui Wu, Changming Wang, Zongpan Ke, Ping Xiang, Xuechun Hu, Jun Xiao
Summary: This study aimed to assess the association of BMI and waist-hip ratio (WHR) with semen quality. The results showed that BMI was weakly associated with sperm progressive motility, while WHR had no relationship with semen parameters. Additionally, underweight individuals had a higher rate of azoospermia, while overweight individuals had lower sperm concentration.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Judit Munoz-Hernando, Joaquin Escribano, Natalia Ferre, Ricardo Closa-Monasterolo, Veit Grote, Berthold Koletzko, Dariusz Gruszfeld, Alice ReDionigi, Elvira Verduci, Annick Xhonneux, Veronica Luque
Summary: This study aimed to compare the ability of the waist-to-height ratio (WHtR) and BMI z-score to predict cardiometabolic risk in children. The findings showed that a WHtR cut-off of >0.55 had better predictive ability at younger ages and can be an effective marker for screening high cardiometabolic risk in the general young European population.
CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Yakubu Lawal, Rifkatu Mshelia-Reng, Special O. Omonua, Kenechukwu Odumodu, Ramatu Shuaibu, Ukamaka D. Itanyi, Amina I. Abubakar, Hadijat O. Kolade-Yunusa, Zumnan D. Songden, Caleb O. Ehusani, Olufemi Adediran, Felicia E. Anumah
Summary: This study aimed to compare waist-height ratio (WHtR) with other obesity indices in predicting peripheral neuropathy in persons with diabetes mellitus (DM). The results showed that WHtR had the highest odds ratio in predicting probable diabetic peripheral neuropathy, followed by waist circumference (WC) and body mass index (BMI).
FRONTIERS IN NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Mahshid Malakootian, Masoumeh Jalilian, Samira Kalayinia, Maryam Hosseini Moghadam, Mona Heidarali, Majid Haghjoo
Summary: This study presents evidence of an association between a nucleotide variation in the DTNA gene and early-onset AF in an Iranian family. The findings further confirm the significant role of genetics in the incidence of early-onset AF and expand the spectrum of gene variations that lead to AF. This discovery may have further implications for the treatment and prevention of AF.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Medical Laboratory Technology
Mahsa Aghajani Mir, Hossein Dinmohammadi, Emadoddin Moudi, Nima Motamed, Abdolreza Daraei
Summary: In prostate cancer, circCDR1AS is significantly upregulated while circHIAT1 is downregulated. circCDR1AS is also expressed at a higher level in patients over the age of 60. These circRNAs may serve as potential biomarkers for prostate cancer.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2022)
Article
Multidisciplinary Sciences
Azam Doustmohammadian, Cain C. T. Clark, Mansooreh Maadi, Nima Motamed, Elham Sobhrakhshankhah, Hossein Ajdarkosh, Mohsen Reza Mansourian, Saeed Esfandyari, Nazanin Asghari Hanjani, Mahsa Nikkhoo, Farhad Zamani
Summary: The study found a favorable association between adherence to the DASH and Mediterranean diets and nonalcoholic fatty liver disease (NAFLD) in Iranian adults, especially women and individuals with or without abdominal obesity.
SCIENTIFIC REPORTS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Elham Zajkani, Mahdi Rahbar, Nima Motamed, Eissa Kordlou
Summary: This study found that bleaching does not affect the microleakage of bulk-fill composites and conventional composites.
INTERNATIONAL JOURNAL OF DENTISTRY
(2022)
Article
Cardiac & Cardiovascular Systems
Nima Motamed, Hossein Ajdarkosh, Mohammad Hadi Karbalaie Niya, Mahshid Panahi, Behzad Farahani, Nader Rezaie, Mehdi Nikkhah, Amir H. Faraji, Gholamreza Hemmasi, Dhayaneethie Perumal, G. Hossein Ashrafi, Fahimeh Safarnezhad Tameshkel, Esmaeel Gholizadeh, Mahmoodreza Khoonsari, Farhad Zamani
Summary: This study evaluated the ability of scoring systems to predict fatal and nonfatal cardiovascular events. The scoring systems showed an independent association with cardiovascular events, particularly those based on structural equation modeling may be useful for women.
CLINICAL CARDIOLOGY
(2022)
Article
Ophthalmology
James D. Cole, Kara M. McHaney, Behnam Rabiee, Jingyi Gao, Carlos Rodriguez, David A. Miller, Mingna Liu, Marta Grannonico, Pedro Norat, Hao F. Zhang, Ali R. Djalilian, Xiaorong Liu
Summary: This study evaluated the long-term efficacy of PD0325901 treatment in aniridia-afflicted subjects, showing significant improvements in retina size, visual acuity, and intraocular pressure, as well as a reduction in the number and size of hotspots in the retina.
EXPERIMENTAL EYE RESEARCH
(2022)
Article
Nutrition & Dietetics
Azam Doustmohammadian, Elham Pishgar, Cain C. T. Clark, Elham Sobhrakhshankhah, Mehdi Nikkhah, Amir Hossein Faraji, Nima Motamed, Mohsen Reza Mansourian, Bahareh Amirkalali, Mansooreh Maadi, Maryam Sadat Kasaii, Hamidreza Ebrahimi, Farhad Zamani
Summary: This study aimed to investigate the association between dietary patterns and nonalcoholic fatty liver disease (NAFLD). The results showed that a western dietary pattern was associated with an increased risk of NAFLD in Iranian males. Furthermore, a mediation effect of dietary acid load was found in the association between healthy, western, and traditional dietary patterns and NAFLD.
FRONTIERS IN NUTRITION
(2022)
Article
Medicine, General & Internal
Azam Doustmohammadian, Ahmad Nezhadisalami, Fahimeh Safarnezhad Tameshke, Nima Motamed, Mansooreh Maadi, Mohammad Farahmand, Masoudreza Sohrabi, Cain C. T. Clark, Hossein Ajdarkosh, Amir Hossein Faraji, Mehdi Nikkhah, Elham Sobhrakhshankhah, Ramin Ebrahimi, Farhad Zamani
Summary: This study aimed to evaluate the efficacy of sitagliptin vs. placebo in treating non-alcoholic fatty liver disease (NAFLD). The results showed that sitagliptin reduced fibrosis scores and liver enzymes in NAFLD patients, especially in normal-weight and overweight individuals.
FRONTIERS IN MEDICINE
(2022)
Article
Nutrition & Dietetics
Azam Doustmohammadian, Sakineh Nouri Saeidlou, Saeed Esfandyari, Esmaeel Gholizadeh, Mansooreh Maadi, Nima Motamed, Hossein Ajdarkosh, Mahmoodreza Khoonsari, Cain C. T. Clark, Farhad Zamani
Summary: The study investigated the association between adherence to DASH and MeD diets and NAFLD. The authors found that DAL, HbA1c, and MeS mediate this association.
FRONTIERS IN NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Amir Farjam Fazelifar, Nina Jalily Taghavyan, Mahdi Moeeni, Bahador Baharestani, Farshad Jalili Shahandashti, Majid Haghjoo, Saeed Hoseini, Farzad Kamali, Shabnam Madadi, Ali Asghar Yoonesi, Sogol Koolaji
Summary: This study aimed to assess the long-term function of bipolar steroid-eluting and unipolar nonsteroid-eluting epicardial pacemakers. The results showed that bipolar steroid-eluting leads have a better survival rate compared to unipolar nonsteroid-eluting leads and are not significantly affected by patient age, suggesting they could be an excellent alternative for endocardial pacemakers.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Aziz Rezapour, Mahsa Tashakori-Miyanroudi, Majid Haghjoo, Mohammad Barzegar, Parvin Tatarpour, Aghdas Souresrafil, Hassan Abolghasem Gorji, Negar Yousefzadeh, Mohammadreza Sheikhy-Chaman
Summary: This study systematically reviewed the economic evaluation of adding dapagliflozin to standard care in patients with heart failure with reduced ejection fraction (HFrEF). The findings suggest that the addition of dapagliflozin to standard care is cost-effective in most countries.
AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS
(2023)
Article
Nutrition & Dietetics
Azam Doustmohammadian, Bahareh Amirkalali, Esmaeel Gholizadeh, Mahmoodreza Khoonsari, Amir Hossein Faraji, Mehdi Nikkhah, Mansooreh Maadi, Nima Motamed, Mohsen Reza Mansourian, Melika Hajjar, Cain C. T. Clark, Samira Chaibakhsh, Fahimeh Safarnezhad Tameshkel, Arian Afzali, Farhad Zamani
Summary: This study investigates the association between Dietary Diversity Score (DDS) and nonalcoholic fatty liver disease (NAFLD) using structural equation modeling (SEM). The results suggest that meat diversity is positively associated with NAFLD prevalence, while vegetable and fruit diversity is negatively associated with NAFLD prevalence.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Cardiac & Cardiovascular Systems
Mahdiye Mehdinejadshani, Hamidreza Fallah, Farzad Kamali, Abolfath Alizadeh-Diz, Masoud Eslami, Allahyar Golabchi, Mehdi Taherpour, Javad Shahabi, Reza Mollazadeh, Shabnam Madadi, Amir Azhari, Abdolhossein Sodagar, Mahmoud Eftekharzadeh, Saeed Oraii, Amirfarjam Fazelifar, Ali Kazemisaeed, Alireza Ghorbanisharif, Mohammad Dalili, Mohammadrafie Khorgami, Alireaza Heidari-Bakavoli, Mohammadvahid Jorat, Hossein Nikoo, Jalal Kheirkhah, Mehrdad Saravi, Morteza Khodaparast, Mansour Mirzaali, Zahra Emkanjoo, Mehrdad Mirmasoumi, Saeed Sadeghian, Meisam Mokhtari, Mohammadtaghi Hedayati-Goudarzi, Majid Haghjoo
Summary: In the Iran S-ICD registry, 223 patients underwent S-ICD implantation, and the results showed that S-ICDs were effective at detecting and treating arrhythmias, with minimal complications.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Multidisciplinary Sciences
M. Yahya Ahmed, Nadia Aziz Salman, Sarbjinder Sandhu, M. Okan Cakir, Alan M. Seddon, Christian Kuehne, G. Hossein Ashrafi
Summary: Human papillomavirus (HPV) infection has been linked to multiple cancers and there have been conflicting studies regarding the presence of high-risk HPV in prostate cancer (PCa). This study, the first of its kind in the UK, analyzed prostate tissues for the presence of high-risk HPV DNA and confirmed its existence in 32.7% of analyzed samples, with HPV 35 being the most frequent type. Additionally, the study found a higher positivity rate of high-risk HPV in abnormal prostate tissues compared to normal prostate condition. The expression of HPV E7 protein in HPV DNA positive prostate tissues further suggests a potential relationship between HPV and the progression of certain cases of prostate cancer.
SCIENTIFIC REPORTS
(2023)