MiR-145 promotes TNF-α-induced apoptosis by facilitating the formation of RIP1-FADDcaspase-8 complex in triple-negative breast cancer

Low miR-145 expression level is associated with poor pathological differentiation and poor prognosis in non-small cell lung cancer

(2015) Hua Shen et al.   BIOMEDICINE & PHARMACOTHERAPY

miR-145 suppress the androgen receptor in prostate cancer cells and correlates to prostate cancer prognosis

(2015) Olivia Larne et al.   CARCINOGENESIS

miR-181b promotes chemoresistance in breast cancer by regulating Bim expression

(2015) YABING ZHENG et al.   ONCOLOGY REPORTS

Tumor suppressor miR-145 reverses drug resistance by directly targeting DNA damage-related gene RAD18 in colorectal cancer

(2015) Rui-Lei Liu et al.   TUMOR BIOLOGY

miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells

(2015) Su’e Chang et al.   Oncotarget

A novel recombinant slow-release TNF α-derived peptide effectively inhibits tumor growth and angiogensis

(2015) Yi Ma et al.   Scientific Reports

TNF- -mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes

(2014) S. Roberge et al.   CARDIOVASCULAR RESEARCH

BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs

(2014) Brian Leibowitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversifying microRNA sequence and function

(2013) Stefan L. Ameres et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

miR-29b, miR-205 and miR-221 Enhance Chemosensitivity to Gemcitabine in HuH28 Human Cholangiocarcinoma Cells

(2013) Kinya Okamoto et al.   PLoS One

Emerging targeted therapies in triple-negative breast cancer

(2012) J. Crown et al.   ANNALS OF ONCOLOGY

MicroRNA and cancer

(2012) Martin D. Jansson et al.   Molecular Oncology

RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex

(2012) B A Abhari et al.   ONCOGENE

Triple-negative breast cancer: are we making headway at least?

(2012) Monica Arnedos et al.   Therapeutic Advances in Medical Oncology

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF

(2011) A-L Mahul-Mellier et al.   CELL DEATH AND DIFFERENTIATION

Tumor necrosis factor-mediated cell death: to break or to burst, that’s the question

(2010) Franky Van Herreweghe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enhancement of TRAIL cytotoxicity by AG-490 in human ALL cells is characterized by downregulation of cIAP-1 and cIAP-2 through inhibition of Jak2/Stat3

(2009) Paola Lanuti et al.   CELL RESEARCH

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL