Editorial Material
Biochemistry & Molecular Biology
Simon W. Townsend, Alexis Hervais-Adelman
Summary: The study found that dogs and humans may segment speech in similar ways when listening to it.
Editorial Material
Microbiology
James E. Crowe, Robert H. Carnahan
Summary: The paper provides a comprehensive investigation into the molecular and functional basis of 17D vaccine responses, as well as the differences in antibody neutralization between the 17D and related African lineage strains and contemporary Central/South American strains.
CELL HOST & MICROBE
(2022)
Article
Business
Yi-Hou Huang, Woan-lih Liang, Quang-Thai Truong, Yanzhi Wang
Summary: This study found that U.S. listed firms with a higher percentage of old directors are more likely to engage in innovation activities, especially in companies with less experienced board members, low meeting frequency of boards, lower institutional ownership, CEO duality, and/or a less competitive product market.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2022)
Review
Chemistry, Multidisciplinary
Athanassios K. Boudalis
Summary: This review presents the history of study on spin triangles, discusses the parallel development of new experimental investigations and new theoretical ideas, as well as their chemical diversity and relevance to spintronic devices and new physics.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Review
Medicine, General & Internal
Theano Penlioglou, Anca Pantea Stoian, Nikolaos Papanas
Summary: The review summarizes the latest data on the relationship between diabetes mellitus and stroke, including risk factors, prevention, and biomarkers. Progress has been made in prevention and early diagnosis, but there are still crucial points that remain controversial and need further clarification.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Martijn A. Nolte, Esther N. M. Nolte-'t Hoen, Coert Margadant
Summary: Integrins, transmembrane receptors promoting cell adhesion and migration, play a crucial role in regulating endocytosis and exocytosis across a variety of cell types by interacting with intracellular trafficking machinery. Recent insights have shown integrins' involvement in processes like degranulation, mechanotransduction, cell-cell communication, antibody production, virus entry, and Toll-like receptor signaling.
TRENDS IN BIOCHEMICAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Gil Meir Leizerowitz, Ran Gabai, Meir Plotnik, Ofer Keren, Avi Karni
Summary: It is often overlooked that young healthy adults can substantially improve in activities that are part of their daily routine. In this study, researchers followed the effects of repeated executions of the Timed-Up-and-Go (TUG) task in young healthy adults, and found that task execution times improved robustly and were well retained even after a week.
Editorial Material
Biology
Alexandre Faille, Alan J. Warren
Summary: Understanding how streptomycin binds to the small subunit of the mitoribosome may aid in the development of less toxic derivatives of this antibiotic.
Article
Biochemistry & Molecular Biology
Katie A. Frye, Kacper M. Sendra, Kevin J. Waldron, Thomas E. Kehl-Fie
Summary: Superoxide dismutases are ancient enzymes that are widely present in all domains of life. Recent studies on bacterial pathogens have challenged established dogmas and revealed the diverse repertoire and adaptive nature of SODs in response to hostile environments.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Maja Bencun, Thiago Britto-Borges, Jessica Eschenbach, Christoph Dieterich
Summary: Cardiovascular disease is the leading cause of morbidity and mortality worldwide. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have been used as an in vitro model to study cardiac disease and identify novel miRNA-mRNA interactions. By integrating whole transcriptome and small RNA sequencing data, we discovered new miRNA-mRNA interactions. Experimental validation showed that our approach can distinguish true from false miRNA target predictions.
Article
Endocrinology & Metabolism
Samuel M. Lockhart, Stephen O'Rahilly
Summary: Colchicine, an anti-inflammatory agent commonly used to treat gout, exerts its effects in mice by inducing the hormone GDF-15 in the liver, as demonstrated by Weng et al. in the latest issue of Nature Metabolism.
Article
Pharmacology & Pharmacy
Egor Shekunov, Polina D. Zlodeeva, Svetlana S. Efimova, Anna A. Muryleva, Vladimir V. Zarubaev, Alexander Slita, Olga S. Ostroumova
Summary: With the resurgence of the coronavirus pandemic, finding alternative strategies for antiviral therapy and targeting the viral lipid envelope have become important. This study investigated the effects of eleven cyclic lipopeptides (CLPs) on liposome fusion and demonstrated their relation to alterations in lipid packing, membrane curvature stress, and domain organization. The antiviral effects of CLPs, such as aculeacin A, anidulafugin, iturin A, and mycosubtilin, were evaluated and found to attenuate the cytopathogenicity of SARS-CoV-2 without specific toxicity.
ANTIVIRAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Christoph Riesinger, David Roehner, Ingo Krossing, Manfred Scheer
Summary: A rational synthetic pathway was developed to synthesize a series of cyclo-P-5-bearing multi-decker complexes. By combining [Cp*Fe(mu,eta(5 : 5)-P-5)] (A) with low-valent transition metal cations, triple-decker complexes [Cp*Fe(mu,eta(5 : 5)-P-5)MCp '''][WCA] (M = Cr - Ni; WCA = weakly coordinating anion, Cp ''' = 1,2,4-(Bu3C5H2)-Bu-t) were obtained. Utilizing arene complexes [M(C6R6)(2)][WCA](n) (M = Fe, Co) allowed the synthesis of unprecedented cyclo-P-5-containing quadruple-decker complexes [{Cp*Fe(mu,eta(5 : 5)-P-5)}(2)M][pf](n) (M = Fe, Co).
CHEMICAL COMMUNICATIONS
(2023)
Article
Veterinary Sciences
Shlomit Flaisher-Grinberg
Summary: The study shows that integrating a canine training program into undergraduate psychology curriculum can significantly improve the behavior of shelter dogs. Most dogs trained by students passed the AKC-CGC test and were successfully adopted into their forever homes.
JOURNAL OF APPLIED ANIMAL WELFARE SCIENCE
(2021)
Editorial Material
Cell & Tissue Engineering
Daniel Rosenblum, Shruti Naik
Summary: By utilizing single-cell transcriptomics to study human skin cells, Reynolds et al. (2021) identified fetal programs in dermatological diseases, shedding light on potential mechanisms driving inflammatory pathology.
