High-Content Analysis Provides Mechanistic Insights into the Testicular Toxicity of Bisphenol A and Selected Analogues in Mouse Spermatogonial Cells

Urinary Bisphenol A Levels in Young Men: Association with Reproductive Hormones and Semen Quality

(2017) Tina Harmer Lassen et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effect of bisphenol S exposure on male reproductive system of rats: A histological and biochemical study

(2016) Hizb Ullah et al.   CHEMOSPHERE

From BPA to its analogues: Is it a safe journey?

(2016) Afia Usman et al.   CHEMOSPHERE

Combined Effects of High-Dose Bisphenol A and Oxidizing Agent (KBrO3) on Cellular Microenvironment, Gene Expression, and Chromatin Structure of Ku70-deficient Mouse Embryonic Fibroblasts

(2016) Natalie R. Gassman et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast™ High-Throughput Data

(2016) Scott Auerbach et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bisphenol Analogues Other Than BPA: Environmental Occurrence, Human Exposure, and Toxicity—A Review

(2016) Da Chen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

In vitroprofiling of toxicity and endocrine disrupting effects of bisphenol analogues by employing MCF-7 cells and two-hybrid yeast bioassay

(2016) Bingli Lei et al.   ENVIRONMENTAL TOXICOLOGY

Evaluation of food-relevant chemicals in the ToxCast high-throughput screening program

(2016) Agnes L. Karmaus et al.   FOOD AND CHEMICAL TOXICOLOGY

Bisphenol A Impairs Mature Sperm Functions by a CatSper-Relevant Mechanism

(2016) Hua-Feng Wang et al.   TOXICOLOGICAL SCIENCES

Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries

(2016) Katie Paul Friedman et al.   TOXICOLOGICAL SCIENCES

High-Content Assays for Characterizing the Viability and Morphology of 3D Cancer Spheroid Cultures

(2015) Oksana Sirenko et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Effects of Low-Dose Bisphenol A on DNA Damage and Proliferation of Breast Cells: The Role of c-Myc

(2015) Daniella Pfeifer et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound

(2015) Soria Eladak et al.   FERTILITY AND STERILITY

γ-H2AX induced by linear alkylbenzene sulfonates is due to deoxyribonuclease-1 translocation to the nucleus via actin disruption

(2015) Xiaoxu Zhao et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Cell cycle staging of individual cells by fluorescence microscopy

(2015) Vassilis Roukos et al.   Nature Protocols

Comparison of toxicogenomic responses to phthalate ester exposure in an organotypic testis co-culture model and responses observed in vivo

(2015) Sean Harris et al.   REPRODUCTIVE TOXICOLOGY

Adverse Outcome Pathways for Regulatory Applications: Examination of Four Case Studies With Different Degrees of Completeness and Scientific Confidence

(2015) Edward J. Perkins et al.   TOXICOLOGICAL SCIENCES

Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor

(2015) Maarke J.E. Roelofs et al.   TOXICOLOGY

Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins

(2014) X. Xiao et al.   HUMAN REPRODUCTION

High-Content, High-Throughput Screening for the Identification of Cytotoxic Compounds Based on Cell Morphology and Cell Proliferation Markers

(2014) Heather L. Martin et al.   PLoS One

Exposure to Low-Dose Bisphenol A Impairs Meiosis in the Rat Seminiferous Tubule Culture Model: A Physiotoxicogenomic Approach

(2014) Sazan Ali et al.   PLoS One

High Content Analysis Provides Mechanistic Insights on the Pathways of Toxicity Induced by Amine-Modified Polystyrene Nanoparticles

(2014) Sergio Anguissola et al.   PLoS One

Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors

(2014) René Habert et al.   REPRODUCTION

The γH2AX Assay for Genotoxic and Nongenotoxic Agents: Comparison of H2AX Phosphorylation with Cell Death Response

(2014) Teodora Nikolova et al.   TOXICOLOGICAL SCIENCES

In vitro testicular toxicity models: Opportunities for advancement via biomedical engineering techniques

(2014) Louise Parks Saldutti   ALTEX-Alternatives to Animal Experimentation

Mutagenicity and DNA Damage of Bisphenol a and its Structural Analogues in Hepg2 Cells

(2013) Anja Fic et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

Direct transdifferentiation of spermatogonial stem cells to morphological, phenotypic and functional hepatocyte-like cells via the ERK1/2 and Smad2/3 signaling pathways and the inactivation of cyclin A, cyclin B and cyclin E

(2013) Zhenzhen Zhang et al.   Cell Communication and Signaling

Genotoxic potentials and related mechanisms of bisphenol A and other bisphenol compounds: A comparison study employing chicken DT40 cells

(2013) Sangwoo Lee et al.   CHEMOSPHERE

Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility

(2013) Dinesh Tiwari et al.   REPRODUCTIVE TOXICOLOGY

Bisphenol A and human health: A review of the literature

(2013) Johanna R. Rochester   REPRODUCTIVE TOXICOLOGY

A High-Throughput Screen for Teratogens Using Human Pluripotent Stem Cells

(2013) Sei Kameoka et al.   TOXICOLOGICAL SCIENCES

A high content screening assay to predict human drug-induced liver injury during drug discovery

(2013) Mikael Persson et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management

(2012) Robert Kavlock et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Urinary Bisphenol A Concentrations and Implantation Failure among Women Undergoing in Vitro Fertilization

(2012) Shelley Ehrlich et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Evaluation of the cytotoxicity of organic dust components on THP1 monocytes-derived macrophages using high content analysis

(2012) Eve Ramery et al.   ENVIRONMENTAL TOXICOLOGY

Effects of bisphenol A on the proliferation and cell cycle of HBL-100 cells

(2012) Shuang Wu et al.   FOOD AND CHEMICAL TOXICOLOGY

Induction and Persistence of Abnormal Testicular Germ Cells Following Gestational Exposure to Di-(n-Butyl) Phthalate in p53-Null Mice

(2012) C. M. Saffarini et al.   JOURNAL OF ANDROLOGY

Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia

(2012) Benjamin E.G. Lucas et al.   TOXICOLOGY

Bisphenol AF may cause testosterone reduction by directly affecting testis function in adult male rats

(2012) Yixing Feng et al.   TOXICOLOGY LETTERS

Spatial coordination between cell and nuclear shape within micropatterned endothelial cells

(2012) Marie Versaevel et al.   Nature Communications

Use of the γH2AX assay for assessing the genotoxicity of bisphenol A and bisphenol F in human cell lines

(2011) Marc Audebert et al.   ARCHIVES OF TOXICOLOGY

Peroxisome Proliferator-Activated Receptor γ Is a Target for Halogenated Analogs of Bisphenol A

(2011) Anne Riu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Urinary bisphenol A and obesity: NHANES 2003–2006

(2011) Jenny L. Carwile et al.   ENVIRONMENTAL RESEARCH

Bisphenol A impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: An in vivo and in silico study

(2011) Shereen Cynthia D’Cruz et al.   FOOD AND CHEMICAL TOXICOLOGY

Impact of Early-Life Bisphenol A Exposure on Behavior and Executive Function in Children

(2011) J. M. Braun et al.   PEDIATRICS

Bisphenol A Disrupts Steroidogenesis in Human H295R Cells

(2011) Xiaowei Zhang et al.   TOXICOLOGICAL SCIENCES

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Daily intake of bisphenol A and potential sources of exposure: 2005–2006 National Health and Nutrition Examination Survey

(2010) Judy S LaKind et al.   Journal of Exposure Science and Environmental Epidemiology

The role of actin and myosin during spermatogenesis

(2010) Xiao Sun et al.   MOLECULAR BIOLOGY REPORTS

Association of Urinary Bisphenol A Concentration with Heart Disease: Evidence from NHANES 2003/06

(2010) David Melzer et al.   PLoS One

Silver Nanoparticles Disrupt GDNF/Fyn kinase Signaling in Spermatogonial Stem Cells

(2010) Laura K. Braydich-Stolle et al.   TOXICOLOGICAL SCIENCES

Low Doses of Bisphenol A Promote Human Seminoma Cell Proliferation by Activating PKA and PKG via a Membrane G-Protein–Coupled Estrogen Receptor

(2009) Adil Bouskine et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood-testis barrier integrity in the seminiferous epithelium

(2009) Pearl P. Y. Lie et al.   FASEB JOURNAL

Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly

(2009) M. Webster et al.   JOURNAL OF CELL SCIENCE

Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells

(2009) Nady Golestaneh et al.   REPRODUCTION

Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity: Lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates

(2009) Xiaozhong Yu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulation of Spermatogonial Stem Cell Self-Renewal in Mammals

(2008) Jon M. Oatley et al.   Annual Review of Cell and Developmental Biology

The Molecular Signature of Spermatogonial Stem/Progenitor Cells in the 6-Day-Old Mouse Testis1

(2008) Maria Kokkinaki et al.   BIOLOGY OF REPRODUCTION

Screening of 397 Chemicals and Development of a Quantitative Structure−Activity Relationship Model for Androgen Receptor Antagonism

(2008) Anne Marie Vinggaard et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Association of Urinary Bisphenol A Concentration With Medical Disorders and Laboratory Abnormalities in Adults

(2008) Iain A. Lang   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Evaluation of aneugenic effects of bisphenol A in somatic and germ cells of the mouse

(2008) F. Pacchierotti et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Neutral red uptake assay for the estimation of cell viability/cytotoxicity

(2008) Guillermo Repetto et al.   Nature Protocols

Assessment of Chemical Effects on Neurite Outgrowth in PC12 cells Using High Content Screening

(2008) Nicholas M. Radio et al.   TOXICOLOGICAL SCIENCES

Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

(2008) Jinghai J. Xu et al.   TOXICOLOGICAL SCIENCES

Exposure of the U.S. Population to Bisphenol A and 4- tertiary -Octylphenol: 2003–2004

(2007) Antonia M. Calafat et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Gdnf Upregulates c-Fos Transcription via the Ras/Erk1/2 Pathway to Promote Mouse Spermatogonial Stem Cell Proliferation

(2007) Zuping He et al.   STEM CELLS