Article
Chemistry, Physical
Giovanna Bosica, Riccardo De Nittis, Ryan Borg
Summary: An efficient and environmentally benign one-pot condensation reaction was achieved using 1,4-diazabicyclo[2-2-2]octane supported on Amberlyst-15 as a novel catalyst. The reaction involved cyclic diketones, aldehydes, and naphthols, resulting in the synthesis of various benzoxanthenones with good to excellent yields. The advantages of this reaction include the use of a heterogeneous catalyst, solventless conditions, atom-economical methodology, and low E-factor values. Seventeen xanthene derivatives, including two novel molecules, were synthesized and characterized. Aromatic aldehydes with electron-withdrawing groups showed excellent yields, and aliphatic aldehydes also gave appreciable results. The catalyst exhibited full recyclability and could be reused up to six times.
Article
Chemistry, Physical
Xavier Abel-Snape, Gina Wycich, Mark Lautens
Summary: A palladium-catalyzed three-component domino reaction for accessing indene derivatives is described. The reaction involves the sequential formation of three bonds, with the first two resulting from inter- and intramolecular carbopalladation, and the final bond arising from an attack by a terminating nucleophilic reagent. The starting tether on the iodoarene can be modified to yield either indenes or benzofulvenes. Additionally, the use of an oxabicycle as an acetylene surrogate is demonstrated, and the enantioselective synthesis of indenes is preliminarily explored.
Article
Chemistry, Physical
Jing Zhang, Zhiyong Hu, Lan Qin, Yang Gao, Xiao-Qiang Hu
Summary: A dual phosphine/rhodium catalysis was reported for the direct synthesis of unsymmetrical tetrasubstituted alkenes. This method effectively provided diverse carboxyl acid-based tetrasubstituted alkenes through a synergistic merger of phosphine-mediated hydration and rhodium-catalyzed arylation. The resulting carboxylate groups served as universal tags for the synthesis of unsymmetrical tetraarylethenes, demonstrating its utility in material development and drug discovery.
Article
Chemistry, Applied
Heng-Tong Qu, Zeng-Hui Wu, Guo-Chen Zhong, Yan-Chun Zhang, Cheng-Tao Feng, Kun Xu
Summary: An aerobic Mn(III)-catalyzed one-pot three-component synthesis of 5-cyano-pyrazolo[1,5-a]pyrimidines has been developed, which relies on the synergistic combination of Strecker reaction and oxidatively-induced 6 pi-azacyclization. This protocol offers a step-economic, regioselective, and functionally tolerant strategy to obtain 5-cyano-pyrazolo[1,5-a]pyrimidines, distinct from previous reports using toxic cyanating agents or multistep synthesis.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Faranak Manteghi, Fatemeh Zakeri, Owen James Guy, Zari Tehrani
Summary: A chromium-containing metal-organic framework MIL-101 was effectively used as a heterogeneous catalyst for the solvent-free synthesis of 2,4,5-trisubstituted imidazoles, showing advantages such as high efficiency, reusability, and ease of isolation. The catalytic reaction achieved a high yield in a short time, making it a promising alternative to other catalysts.
Article
Chemistry, Physical
Yuan Ji, Wanning Gao, Muhammad Sohail, Lei Lin, Xing Zhang
Summary: This article introduces a post-modification method with adjustable apertures to reduce the influence of micropores in Metal-organic frameworks (MOFs) on the activity of bio-catalysts in solvent-free and viscous reaction systems. The synthesized defected lipase-MOF composites (CRL@dZIF-90) efficiently catalyze esterification reactions in solvent-free systems to synthesize phytosterol esters (conversion to stigmasterol conjugated linoleate ester up to 95%). The activity of CRL@dZIF-90 remains above 80% after 5 cycles and 85% after one-month storage, demonstrating the potential of post-modification to enhance the activity of enzyme@MOF bio-composites in solvent-free systems.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Organic
Baofu Zhu, Jiaming He, Kai Zou, Anquan Li, Chen Zhang, Jiaji Zhao, Hua Cao
Summary: This study established a three-component reaction catalyzed by base, involving ynals, isocyanates, amines, and alcohols. The strategy enables a wide range of substrates and provides a simple process for the preparation of diverse pyridine derivatives with good yields and high regioselectivities.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Jian Tian, Lulu Zhao, Chuan Yang, Chao Yang, Lin Guo, Wujiong Xia
Summary: Metal-free heterogeneous catalysis is a promising strategy for the synthesis of valuable imidazolidines. In this study, a photocatalytically active carbon nitride-based heterogeneous catalyst was prepared from melamine and glyoxal. This catalyst, denoted as 1.0 Ci-C3N4, showed visible light harvesting capacity and catalytic activity, enabling the four-component synthesis of spiro-imidazolidines under visible light irradiation. The catalyst exhibited a broad substrate scope, good functional group tolerance, and easy recovery and recycling, making it suitable for industrial manufacture.
Article
Chemistry, Applied
Eliana Nope, Angel G. Sathicq, Jose J. Martinez, Hugo Rojas, Gustavo Romanelli
Summary: This study successfully utilized layered double hydroxides to facilitate the multicomponent synthesis of uracil derivatives under green chemistry conditions, achieving high yields. Consideration of weak basic sites and solvent-free conditions during the reaction process played a significant role in the reaction efficiency.
Article
Chemistry, Physical
Alka Karn, Chetna Yadav, Ajay Kumar Sahoo, Jarugu Narasimha Moorthy
Summary: A porous organic polymer (POP) with carboxylic acid functionalities, known as Carboxy-POP, has been developed for efficient heterogeneous catalytic reactions. The catalyst exhibits high catalytic activity, easy operation, high yields, short reaction times, and good recyclability.
Article
Chemistry, Physical
Shan Ding, Yuxiang Zhang, Fengqian Lou, Ming Li, Qi Huang, Kang Yang, Baokai Xia, Cheng Tang, Jingjing Duan, Markus Antonietti, Sheng Chen
Summary: This study reports a novel oxygen-vacancy-type Mars-van Krevelen mechanism for promoting the electrochemical oxygen reduction reaction (ORR). The structural oxygen vacancies of zinc oxide catalysts effectively alter the electron densities of nearby metal active sites, facilitating the adsorption and activation of O-2. Experimental results demonstrate that the catalyst electrode designed based on this mechanism exhibits superior ORR activities with high Faradaic efficiency.
MATERIALS TODAY ENERGY
(2023)
Article
Engineering, Environmental
Evamaria Hofmann, Lena Schmauser, Julia Neugebauer, Didier Touraud, Fabrice Gallou, Werner Kunz
Summary: A cascade reaction involving a Heck reaction and an enzyme-catalyzed reaction was conducted in different aqueous solutions, and the impact of solvent structuring was investigated. Surfactant-free microemulsions were found to be the most effective solvent for the reaction, allowing for a reduction in reaction temperature. The study also revealed that the presence of surfactants is not the main factor enabling organic reactions in water, but rather the solubility and stability of the reaction components.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Giovanna Bosica, Fiona Cachia, Riccardo De Nittis, Nicole Mariotti
Summary: Multicomponent reactions offer economic and environmental advantages, with the Biginelli reaction being a significant method for synthesizing 3,4-dihydropyrimidin-2(1H)-ones (DHPMs). In this study, silicotungstic acid supported on Ambelyst-15 was used as a catalyst for the Biginelli reaction under solventless conditions, resulting in improved reaction yields.
Review
Chemistry, Inorganic & Nuclear
Leandros P. Zorba, Georgios C. Vougioukalakis
Summary: Green chemistry and sustainable catalysis are gaining more attention, with multicomponent reactions such as the A(3) coupling offering a superior, more efficient approach compared to traditional methods.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Wei-Bao He, Sai-Jie Zhao, Jing-Yang Chen, Jun Jiang, Xiang Chen, Xinhua Xu, Wei-Min He
Summary: A practical method for the synthesis of 4-thiocyanato-1H-pyrazoles was established through an electrochemical cascade reaction of hydrazines, 1,3-diones and NH4SCN under metal-, chemical oxidant- and external electrolyte-free conditions. Importantly, both a gram-scale synthesis of 4-thiocyanato-1H-pyrazoles and five one-pot sequential transformations starting from hydrazine were successfully achieved.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Physical
Dinesh Kumar Subbiah, Apurba Das, John Bosco Balaguru Rayappan
Summary: Utilizing nanostructured materials modified cotton cellulose for developing protective fabrics with UV blocking and thermo-chromic properties is a versatile and cost-effective solution. The surface modification of cotton cellulose with hydrated non-stoichiometric tungsten oxide enhances UV blocking features and shows ligand to metal charge transfer characteristics, demonstrating potential for protective clothing applications.
APPLIED SURFACE SCIENCE
(2021)
Review
Engineering, Chemical
Selva Balasubramanian, Arockia Jayalatha Kulandaisamy, K. Jayanth Babu, Apurba Das, John Bosco Balaguru Rayappan
Summary: The paper provides a comprehensive review of the history, toxicity, and detoxification research of chemical warfare agents (CWAs), highlighting the advantages and application prospects of metal-organic frameworks (MOFs) as effective degrading agents, as well as the practical application challenges on textiles.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2021)
Article
Chemistry, Physical
Subbiah Thamotharan, Subramaniyan Prasanna Kumari, Subramaniapillai Selva Ganesan, Shankar Madan Kumar, M. Judith Percino, Neratur Krishnappagowda Lokanath
Summary: Two different classes of compounds, xanthenedione and acridinedione derivatives, have been synthesized and their crystal structures have been reported. The experimental results reveal distinct conformational features and intermolecular interaction patterns between the two compounds, which may lead to differences in the stability of their crystal structures.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Computer Science, Artificial Intelligence
C. Lakshmi, K. Thenmozhi, C. Venkatesan, A. Seshadhri, John Bosco Balaguru Rayappan, Rengarajan Amirtharajan
Summary: The paper discusses the growth and challenges in the field of image encryption and introduces a new encryption scheme with higher bitplane confusion to resist chosen-plaintext attacks. Neural assisted techniques are proposed as the solution to meet encryption requirements.
NEURAL PROCESSING LETTERS
(2021)
Article
Engineering, Electrical & Electronic
Santhiya R. Devi, K. Thenmozhi, John Bosco Balaguru Rayappan, Rengarajan Amirtharajan, Padmapriya Praveenkumar
Summary: This study introduces a novel architecture based on Quantum Cellular Automata (QCA) for communication, utilizing majority gates in cross-coupled and cross-oriented structures. By optimizing the Random Key Generator and image encryption algorithm, the security of image encryption is effectively enhanced.
NANO COMMUNICATION NETWORKS
(2021)
Article
Chemistry, Multidisciplinary
Pavithira Suresh, Subbiah Thamotharan, Subramaniapillai Selva Ganesan
Summary: Metal-free N-heterocyclic carbene (NHC) organocatalysis in D2O medium was elegantly used for the synthesis of highly diastereoselective deuterated spiropyran derivatives, achieving selective deuteration on the C5 carbon atom of the pyran ring and proving through quantum chemical calculations the preferential formation of a single diastereomer out of the possible four. The scope of NHC organocatalysis in D2O was further expanded for the synthesis of deuterated spirooxindole derivative.
Article
Chemistry, Physical
Madeshwari Ezhilan, Arockia J. B. B. Jayalatha, K. Jayanth Babu, John Bosco Balaguru Rayappan
Summary: Low-dimensional metal oxide nanostructures with hierarchical connections have been preferred for gas-sensing applications due to their enhanced sensing response. Hierarchical architectures of WO3 nanowires were synthesized using electrospinning technique, with X-ray diffraction and electron microscopy revealing changes in grain features with calcination temperature. X-ray photoelectron spectrometer showed higher oxidation states of tungsten and increased oxygen vacancies in samples calcined at higher temperatures.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Materials Science, Multidisciplinary
Madeshwari Ezhilan, Arockia J. B. B. Jayalatha, John Bosco Balaguru Rayappan
Summary: V2O5 nanowires based vapor sensors were successfully fabricated using calcinated electrospun nanofibers, with different V2O5 nanowires (NC1, NC2, NC3) synthesized and characterized for their properties. The V2O5 nanowires showed high selectivity towards acetone with quick response and recovery times, indicating their potential for gas sensing applications.
MATERIALS RESEARCH BULLETIN
(2021)
Article
Chemistry, Organic
Singarajanahalli Mundarinti Krishna Reddy, Subramaniyan Prasanna Kumari, Subramaniapillai Selva Ganesan
Summary: The palladium-catalyzed addition of arylboronic acid to 2-cyano-(N-aryl)-acetamide or ethyl-2-cyanoacetate followed by subsequent reaction transforms them into biologically significant derivatives. The reaction conditions are robust enough to prevent hydrolysis of the ester/amide moiety during arylation, and can also convert the unactivated nitrile moiety in acetonitrile to the corresponding acetophenone derivative.
TETRAHEDRON LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Pavithira Suresh, Subramaniyan Prasanna Kumari, Keerthana Krishnan, Subramaniapillai Selva Ganesan
Summary: Readily available aminonaphthol/aminophenol derivatives were successfully converted to the corresponding thioethers under catalyst-free and environmentally friendly conditions. The use of aqueous medium allowed for the transformation of aminonaphthol derivatives to thioethers in the presence of oxygen, while saturated brine solution was found to be suitable for synthesizing thioethers from aminophenol derivatives. Control experiments showed that the nature of leaving group and reaction atmosphere were crucial factors affecting the yield of the products.
Article
Chemistry, Analytical
Priyannth Ramasami Sundhar Baabu, Ganesh Kumar Mani, John Bosco Balaguru Rayappan, Yuichiro Tsuyuki, Toshiyuki Inazu, Kazuyoshi Tsuchiya
Summary: Miniaturization of electrochemical components has become less common in the last decade, but the design and development of state-of-the-art microelectrodes for small volume analysis of samples have been the focus. This work presents a potential paradigm shift in miniaturization by using cheaper alternatives such as plastics to build electrochemical components. Through minimal processing procedures, an electrochemical working electrode based on a micropipette tip was designed and realized, showing potential for low-cost miniaturized sensors to detect various bio-analytes in sample solutions.
Article
Nanoscience & Nanotechnology
Veena Mounasamy, Ganesh Kumar Mani, Kazuyoshi Tsuchiya, Sridharan Madanagurusamy
Summary: This study proposes a strategy for the preparation of freestanding nanosheets using sputtering technique for sensing toxic ammonia (NH3). The evaluated sputtered vanadium pentoxide (V2O5) film showed good sensor response to 5 ppm NH3 at room temperature.
JOURNAL OF SCIENCE-ADVANCED MATERIALS AND DEVICES
(2022)
Article
Computer Science, Artificial Intelligence
C. Lakshmi, K. Thenmozhi, John Bosco Balaguru Rayappan, Sundararaman Rajagopalan, Rengarajan Amirtharajan, Nithya Chidambaram
Summary: Current medical technology involves massive reports like electronic patient records and scanned medical images, which need to be securely stored for future references. Cloud storage services meet the demand with scalability and availability, but users need to take responsibility to preserve medical data. Existing image encryption solutions are vulnerable to attacks and new technologies are needed to improve security.
NEURAL COMPUTING & APPLICATIONS
(2021)
Article
Computer Science, Information Systems
C. Lakshmi, K. Thenmozhi, John Bosco Balaguru Rayappan, Rengarajan Amirtharajan
Summary: This paper introduces a genetic algorithm-based image encryption scheme to enhance statistical measures of grayscale cipher images and improve key space through chaotic mapping, ensuring digital image security. Fitness tests with correlation and entropy analyses confirm its simple, optimized encryption and defense against attacks.
MULTIMEDIA TOOLS AND APPLICATIONS
(2021)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
