期刊
SYNTHESIS-STUTTGART
卷 48, 期 5, 页码 644-652出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0035-1561315
关键词
alpha-alkylation; transfer hydrogenation; ketone; alcohol; catalysis; tandem process
资金
- K & A Wallenberg Foundation
- Swedish Research Council
The formation of secondary alcohol products via a tandem -alkylation/transfer hydrogenation of ketones with primary alcohols is a little explored reaction with unrealized potential for green synthesis. This review covers the current literature in the field, including asymmetric versions of the reaction, and outlines future possibilities and challenges for the methodology. 1 Introduction 2 Formation of Racemic Alcohols 3 Formation of Enantiomerically Enriched Alcohols 4 Conclusions
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