Review
Gastroenterology & Hepatology
Bo Shen
Summary: Endoscopic therapy has become the main treatment for inflammatory bowel diseases and associated complications, such as strictures, fistulas, abscesses, bleeding lesions, and polyps. The development of interventional IBD is supported by a better understanding of the disease process, advancements in endoscopic technology, and the training of next-generation specialists.
GASTROENTEROLOGY REPORT
(2022)
Article
Gastroenterology & Hepatology
Kate E. Lee, Francesca Lim, Adam S. Faye, Bo Shen, Chin Hur
Summary: This study analyzed the cost-effectiveness of endoscopic balloon dilation (EBD) compared to resection surgery for managing Crohn's disease strictures. The results showed that EBD is a cost-effective strategy, considering patient risks and quality of life after intervention.
DIGESTIVE DISEASES AND SCIENCES
(2022)
Article
Gastroenterology & Hepatology
Eyal Klang, Ana Grinman, Shelly Soffer, Reuma Margalit Yehuda, Oranit Barzilay, Michal Marianne Amitai, Eli Konen, Shomron Ben-Horin, Rami Eliakim, Yiftach Barash, Uri Kopylov
Summary: The study tested a deep learning network for detecting intestinal strictures in Crohn's disease patients' capsule endoscopy images. The network exhibited excellent accuracy in distinguishing strictures from normal mucosa as well as different degrees of ulcers, suggesting potential for automated detection and grading of Crohn's disease-related findings.
JOURNAL OF CROHNS & COLITIS
(2021)
Review
Gastroenterology & Hepatology
Mathurin Fumery, Clara Yzet, Denis Chatelain, Thierry Yzet, Franck Brazier, Jean-Philippe Lemouel, David Laharie, Charles Sabbagh
Summary: The management of colorectal stricture complicating inflammatory bowel disease remains challenging, with surgery as the 'gold standard' treatment associated with high morbidity. Current therapeutic strategies for colonic strictures are based on a low level of evidence and applied by analogy with the treatment of ileal strictures.
JOURNAL OF CROHNS & COLITIS
(2021)
Article
Medicine, General & Internal
Soo-Young Na, Yun-Jeong Lim
Summary: Capsule endoscopy has proven to be valuable for diagnosing small bowel diseases, with utility in both CD and UC patients. While having a high diagnostic yield, CE is most cost effective as a third diagnostic test and has potential in the utility of CCE for colon diseases.
Review
Medicine, General & Internal
Virginia Solitano, Alessandra Zilli, Gianluca Franchellucci, Mariangela Allocca, Gionata Fiorino, Federica Furfaro, Ferdinando D'Amico, Silvio Danese, Sameer Al Awadhi
Summary: Artificial intelligence (AI) is increasingly playing a crucial role in various medical fields, particularly in the detection and classification of gastrointestinal lesions during endoscopy. In the field of inflammatory bowel disease (IBD), AI has the potential to overcome human limitations and serve as a powerful tool for precision medicine decision-making. This review discusses the current state-of-the-art and identifies research gaps in the application of AI in endoscopy for IBD at the beginning of 2022.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Tommaso Lorenzo Parigi, Elisabetta Mastrorocco, Leonardo Da Rio, Mariangela Allocca, Ferdinando D'Amico, Alessandra Zilli, Gionata Fiorino, Silvio Danese, Federica Furfaro
Summary: Endoscopy is essential for evaluating inflammatory bowel disease and monitoring colorectal cancer. Advances in virtual chromoendoscopy and artificial intelligence are reshaping the field, while tools like endocytoscopy and pCLE enhance inflammation and dysplasia assessment. The combination of pCLE and molecular labeling may lead to personalized medicine.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Gastroenterology & Hepatology
Paulina Nunez, Noa Krugliak Cleveland, Rodrigo Quera, David T. Rubin
Summary: Endoscopic evaluation plays a crucial role in predicting disease activity and severity in inflammatory bowel diseases, with mucosal healing associated with improved clinical outcomes and incorporated into standard care. Therapeutic endoscopic options and surveillance strategies, including early detection of neoplasia, continue to advance with evolving technology and visualization techniques.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Medicine, General & Internal
Writaja Halder, Faidon-Marios Laskaratos, Hanan El-Mileik, Sergio Coda, Stevan Fox, Saswata Banerjee, Owen Epstein
Summary: The COVID-19 pandemic has heavily impacted healthcare services for patients with chronic diseases. This review explores the use of colon capsule endoscopy as a method for assessing and treating inflammatory bowel disease. Despite its limitations, there is increasing evidence to support the use of the second-generation colon capsule.
Article
Gastroenterology & Hepatology
Markus F. Neurath, Michael Vieth
Summary: Mucosal healing is an important prognostic factor in the management of patients with inflammatory bowel disease. It can predict clinical remission and resection-free survival. There are two levels of mucosal healing: endoscopic healing and histological healing. Drug therapies and new techniques can have an impact on mucosal healing, but cannot provide a definitive cure.
Article
Gastroenterology & Hepatology
Shintaro Akiyama, Akihiro Yamada, Jacob E. Ollech, Yuga Komaki, Fukiko Komaki, Joel Pekow, Sushila R. Dalal, Russell D. Cohen, David T. Rubin, Atsushi Sakuraba
Summary: This study aimed to assess postoperative outcomes and validate the simple endoscopic score to predict Crohn's disease (CD) patients' disease-related outcomes. The findings showed that patients with colon-dominant disease had a higher risk of postoperative clinical recurrence, and SES-CD was effective in predicting postoperative clinical recurrence in CD patients.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Medicine, General & Internal
Celine R. Soriano, Charleston R. Powell, Michael V. Chiorean, Vlad V. Simianu
Summary: Specialized care is often required for the treatment of inflammatory bowel disease (IBD). While outpatient care has become more common, hospitalizations still play a significant role in healthcare utilization for a sizable proportion of IBD patients. The focus on IBD care at the population level includes the shift from inpatient to outpatient care, the balance between emergency and elective hospitalizations, regionalization of specialty care, and the contribution of surgery and endoscopy to hospitalized care.
WORLD JOURNAL OF CLINICAL CASES
(2021)
Article
Gastroenterology & Hepatology
Qingqing Liu, Xiaofei Zhang, Huaibin Mabel Ko, Daniel Stocker, Jordan Ellman, Joyce Chen, Yansheng Hao, Swati Bhardwaj, Yuanxin Liang, Judy Cho, Jean Frederic Colombel, Bachir Taouli, Noam Harpaz
Summary: This study identified and characterized ileal strictures in Crohn's disease, showing that it is primarily caused by mural constriction rather than fibromuscular hypertrophy. The study also found that mesenteric fat wrapping and myenteric plexitis may contribute to the pathogenesis of the strictures.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Medicine, General & Internal
Juho Mattila, Teppo Stenholm, Eliisa Loyttyniemi, Jukka Koffert
Summary: The aim of this study was to find predictive markers for clinically significant small bowel Crohn's disease without the need for small bowel capsule endoscopy. The results indicated that fecal calprotectin, serum albumin, and erythrocyte sedimentation rate were significantly different between patients diagnosed with Crohn's disease and those without. A CECDAI score of 3 could serve as a reasonable cutoff value for small bowel Crohn's disease. Follow-up with fecal calprotectin before small bowel capsule endoscopy may be appropriate for patients without endoscopic ileitis, negative imaging results, and fecal calprotectin levels below 50 ug/g.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Ilyssa O. Gordon, Dominik Bettenworth, Arne Bokemeyer, Amitabh Srivastava, Christophe Rosty, Gert de Hertogh, Marie E. Robert, Mark A. Valasek, Ren Mao, Jiannan Li, Noam Harpaz, Paula Borralho, Reetesh K. Pai, Robert Odze, Roger Feakins, Claire E. Parker, Leonardo Guizzetti, Tran Nguyen, Lisa M. Shackelton, William J. Sandborn, Vipul Jairath, Mark Baker, David Bruining, Joel G. Fletcher, Brian G. Feagan, Rish K. Pai, Florian Rieder
Summary: Effective medical therapy and validated trial outcomes are lacking for small bowel Crohn's disease strictures, highlighting the need for standardized assessment of gross pathology and histopathology to improve clinical trial efficiency and aid drug development.
Letter
Gastroenterology & Hepatology
Thomas R. McCarty, Lamia Haque, Basile Njei
JOURNAL OF CLINICAL GASTROENTEROLOGY
(2019)
Article
Gastroenterology & Hepatology
David E. Kaplan, Marina A. Serper, Rajni Mehta, Rena Fox, Binu John, Ayse Aytaman, Michelle Baytarian, Kristel Hunt, Jeffrey Albrecht, Basile Njei, Tamar H. Taddei
Article
Surgery
Prabin Sharma, Thomas R. McCarty, Siddhartha Yadav, Julius N. Ngu, Basile Njei
Article
Health Care Sciences & Services
Basile Njei, Denise Esserman, Supriya Krishnan, Michael Ohl, Janet P. Tate, Ronald G. Hauser, Tamar Taddei, Joseph Lim, Amy C. Justice
Article
Gastroenterology & Hepatology
Chunwei Walter Lai, Sneha Jadhav, Basile Njei, Aijun Ye, Jean Wactawski-Wende, Sunni L. Mumford, Enrique F. Schisterman, Yaron Rotman
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2020)
Article
Nursing
Thomas R. McCarty, Prabin Sharma, Andrew Lange, Julius N. Ngu, Ashley Davis, Basile Njei
BARIATRIC SURGICAL PRACTICE AND PATIENT CARE
(2020)
Review
Surgery
Thomas R. McCarty, James Farrelly, Basile Njei, Priya Jamidar, Thiruvengadam Muniraj
Summary: This study found that prophylactic cholecystectomy is more effective compared to deferring cholecystectomy for patients post-endoscopic biliary sphincterotomy for common bile duct stones. Further studies may identify specific subsets of patients who may not require cholecystectomy, such as those with large balloon biliary dilation.
Review
Obstetrics & Gynecology
Jodie Dionne-Odom, Gabriella D. Cozzi, Ricardo A. Franco, Basile Njei, Alan T. N. Tita
Summary: Viral hepatitis in pregnancy can be caused by various viruses, and it is important to have a high clinical suspicion and awareness of risk factors for infection. The route of infection varies depending on the virus. Serologic and molecular testing are helpful for diagnosis of viral hepatitis.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Gastroenterology & Hepatology
Mayra J. Sanchez, Sarah Olivier, Furkan Gedikoglu, Mariana Almeida, Marina Gaeta, Mariana Nigro, Randolph de la Rosa, Mytien Nguyen, Mona Lalehzari, Francis Regala, Basile Njei, Yanhong Deng, Maria Ciarleglio, Amir Masoud
Summary: The study found that opioid use is associated with multiple abnormalities on esophageal motility, with effects potentially being dose-dependent. Achalasia type III, esophagogastric junction outflow obstruction, and distal esophageal spasm were more common among opioid users, while ineffective esophageal motility was more common in non-opioid users.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Letter
Gastroenterology & Hepatology
Basile Njei, Thomas R. McCarty, Udayakumar Navaneethan
GASTROINTESTINAL ENDOSCOPY
(2022)
Letter
Gastroenterology & Hepatology
Basile Njei, Thomas R. McCarty, Udayakumar Navaneethan
GASTROINTESTINAL ENDOSCOPY
(2022)
Review
Gastroenterology & Hepatology
Basile Njei, Ulrick Sidney Kanmounye, Nancy Seto, Thomas. R. R. McCarty, Babu. P. P. Mohan, Lydia Fozo, Udayakumar Navaneethan
Summary: This study provides a comprehensive overview of the application of artificial intelligence (AI) in medical imaging for cholangiocarcinoma (CCA) diagnosis. The results showed that China and the United States had the highest number of publications, and convolutional neural networks (CNN) were the most commonly used classifiers. CNN-cholangioscopy demonstrated the highest performance for diagnosing extrahepatic CCA. The analysis also revealed an Asian and American predominance in the research network of AI in CCA diagnosis.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Review
Gastroenterology & Hepatology
Basile Njei, Thomas R. McCarty, Babu P. Mohan, Lydia Fozo, Udayakumar Navaneethan
Summary: This systematic review summarizes the available data on the diagnostic utility of endoscopic AI-based imaging for malignant biliary strictures and cholangiocarcinoma. CNN-based machine learning of cholangioscopy images appears to be the most promising, while CNN-EUS has the best clinical performance application.
ANNALS OF GASTROENTEROLOGY
(2023)
Review
Gastroenterology & Hepatology
Thomas R. McCarty, Ahmad Najdat Bazarbashi, Basile Njei, Marvin Ryou, Harry R. Aslanian, Thiruvengadam Muniraj
CLINICAL ENDOSCOPY
(2020)
Article
Gastroenterology & Hepatology
Basile Njei, Thomas R. McCarty, Thiruvengadam Muniraj, Prabin Sharma, Priya A. Jamidar, Harry R. Aslanian, Shyam Varadarajulu, Udayakumar Navaneethan
ENDOSCOPY INTERNATIONAL OPEN
(2020)