期刊
STROKE
卷 47, 期 5, 页码 1385-1388出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/STROKEAHA.115.012520
关键词
hemiplegia; recovery; rehabilitation; robotics; stroke
资金
- Teijin Pharma Ltd (Tokyo, Japan)
Background and Purpose-Our aim was to study the efficacy of robotic therapy as an adjuvant to standard therapy during poststroke rehabilitation. Methods-Prospective, open, blinded end point, randomized, multicenter exploratory clinical trial in Japan of 60 individuals with mild to moderate hemiplegia 4 to 8 weeks post stroke randomized to receive standard therapy plus 40 minutes of either robotic or self-guided therapy for 6 weeks (7 days/week). Upper extremity impairment before and after intervention was measured using the Fugl-Meyer assessment, Wolf Motor Function Test, and Motor Activity Log. Results-Robotic therapy significantly improved Fugl-Meyer assessment flexor synergy (2.1 +/- 2.7 versus -0.1 +/- 2.4; P<0.01) and proximal upper extremity (4.8 +/- 5.0 versus 1.9 +/- 5.5; P<0.05) compared with self-guided therapy. No significant changes in Wolf Motor Function Test or Motor Activity Log were observed. Robotic therapy also significantly improved Fugl-Meyer assessment proximal upper extremity among low-functioning patients (baseline Fugl-Meyer assessment score <30) and among patients with Wolf Motor Function Test 120 at baseline compared with self-guided therapy (P<0.05 for both). Conclusions-Robotic therapy as an adjuvant to standard rehabilitation may improve upper extremity recovery in moderately impaired poststroke patients. Results of this exploratory study should be interpreted with caution.
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