EGF-Amphiregulin Interplay in Airway Stem/Progenitor Cells Links the Pathogenesis of Smoking-Induced Lesions in the Human Airway Epithelium

Injury Induces Direct Lineage Segregation of Functionally Distinct Airway Basal Stem/Progenitor Cell Subpopulations

(2015) Ana Pardo-Saganta et al.   Cell Stem Cell

Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors

(2015) M. Mori et al.   DEVELOPMENT

Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair

(2015) Dietmar M.W. Zaiss et al.   IMMUNITY

Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung

(2015) Henry Danahay et al.   Cell Reports

FOXJ1 Prevents Cilia Growth Inhibition by Cigarette Smoke in Human Airway EpitheliumIn Vitro

(2014) Angelika Brekman et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Switching on cilia: transcriptional networks regulating ciliogenesis

(2014) S. P. Choksi et al.   DEVELOPMENT

Intraflagellar Transport Gene Expression Associated with Short Cilia in Smoking and COPD

(2014) Justina Hessel et al.   PLoS One

Amphiregulin

(2014) Carmen Berasain et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Human Tracheobronchial Basal Cells. Normal versus Remodeling/Repairing PhenotypesIn VivoandIn Vitro

(2013) Moumita Ghosh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lung adenocarcinoma subtypes based on expression of human airway basal cell genes

(2013) Tomoya Fukui et al.   EUROPEAN RESPIRATORY JOURNAL

EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype

(2013) R. Shaykhiev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amphiregulin-Dependent Mucous Cell Metaplasia in a Model of Nonallergic Lung Injury

(2012) Nicholas D. Manzo et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Fine PM induce airway MUC5AC expression through the autocrine effect of amphiregulin

(2012) Stéphanie Val et al.   ARCHIVES OF TOXICOLOGY

Histamine may induce airway remodeling through release of epidermal growth factor receptor ligands from bronchial epithelial cells

(2012) Nobuaki Hirota et al.   FASEB JOURNAL

EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling

(2012) Kristy J. Wilson et al.   GROWTH FACTORS

Pathophysiology of the Small Airways in Chronic Obstructive Pulmonary Disease

(2012) Simonetta Baraldo et al.   RESPIRATION

Notch-Dependent Differentiation of Adult Airway Basal Stem Cells

(2011) Jason R. Rock et al.   Cell Stem Cell

Cigarette smoke impairs airway epithelial barrier function and cell-cell contact recovery

(2011) I. H. Heijink et al.   EUROPEAN RESPIRATORY JOURNAL

Regulation of epidermal growth factor receptor signalling by inducible feedback inhibitors

(2011) O. Segatto et al.   JOURNAL OF CELL SCIENCE

Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma

(2011) Amandine Hurbin et al.   JOURNAL OF PATHOLOGY

TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells

(2011) Hassan Lemjabbar-Alaoui et al.   PLoS One

The Human Airway Epithelial Basal Cell Transcriptome

(2011) Neil R. Hackett et al.   PLoS One

Presence of a Putative Tumor-Initiating Progenitor Cell Population Predicts Poor Prognosis in Smokers with Non-Small Cell Lung Cancer

(2010) A. T. Ooi et al.   CANCER RESEARCH

Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo

(2010) Renat Shaykhiev et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

(2010) J. R. Rock et al.   Disease Models & Mechanisms

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Efficacy of an Inhaled Epidermal Growth Factor Receptor Inhibitor (BIBW 2948 BS) in Chronic Obstructive Pulmonary Disease

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Essential Role of c-Cbl in Amphiregulin-Induced Recycling and Signaling of the Endogenous Epidermal Growth Factor Receptor†

(2009) Aleksander Baldys et al.   BIOCHEMISTRY

Smoking Is Associated with Shortened Airway Cilia

(2009) Philip L. Leopold et al.   PLoS One

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Effects of EGFR Ligands on Endocytic Sorting of the Receptor

(2009) Kirstine Roepstorff et al.   TRAFFIC

EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate

(2008) Kathryn A. Stern et al.   BIOCHEMICAL JOURNAL

Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop

(2008) Nicole E. Willmarth et al.   CELLULAR SIGNALLING

Plasma-membrane-anchored growth factor pro-amphiregulin binds A-type lamin and regulates global transcription

(2008) M. Isokane et al.   JOURNAL OF CELL SCIENCE