Novel Function of Serine Protease HTRA1 in Inhibiting Adipogenic Differentiation of Human Mesenchymal Stem Cells via MAP Kinase-Mediated MMP Upregulation

Inhibition of MMP-13 prevents diet-induced obesity in mice and suppresses adipogenesis in 3T3-L1 preadipocytes

(2015) Chia-Li M. Shih et al.   MOLECULAR BIOLOGY REPORTS

Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling

(2014) Nathalie Beaufort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress

(2014) Ildiko Kasza et al.   PLoS Genetics

The Emerging Roles of HTRA1 in Musculoskeletal Disease

(2013) André Nicki Tiaden et al.   AMERICAN JOURNAL OF PATHOLOGY

Mapping of matrix metalloproteinase cleavage sites on syndecan-1 and syndecan-4 ectodomains

(2013) Tina Manon-Jensen et al.   FEBS Journal

Laminin Production and Basement Membrane Deposition by Mesenchymal Stem Cells upon Adipogenic Differentiation

(2013) Ariel Noro et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Detrimental Role for Human High Temperature Requirement Serine Protease A1 (HTRA1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration

(2012) André N. Tiaden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Analysis of HtrA1 and Its Subdomains

(2012) Charles Eigenbrot et al.   STRUCTURE

Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma

(2011) Bettina Meissburger et al.   EMBO Molecular Medicine

Basement membrane collagen type IV expression by human mesenchymal stem cells during adipogenic differentiation

(2011) Tarvo Sillat et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Diverse effects of type II collagen on osteogenic and adipogenic differentiation of mesenchymal stem cells

(2011) Li-Hsuan Chiu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Overexpression of HTRA1 Leads to Ultrastructural Changes in the Elastic Layer of Bruch's Membrane via Cleavage of Extracellular Matrix Components

(2011) Sarah Vierkotten et al.   PLoS One

Insulin-sensitive obesity

(2010) Nora Klöting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipocyte extracellular matrix composition, dynamics and role in obesity

(2010) Edwin C. M. Mariman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Adipose tissue remodeling in pathophysiology of obesity

(2010) Mi-Jeong Lee et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress

(2010) Eun-Mee Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease

(2010) S. Vallet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basement Membranes: Cell Scaffoldings and Signaling Platforms

(2010) P. D. Yurchenco   Cold Spring Harbor Perspectives in Biology

Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation

(2009) Chieko Ando et al.   FEBS LETTERS

Stimulation of osteogenic differentiation and inhibition of adipogenic differentiation in bone marrow stromal cells by alendronate via ERK and JNK activation

(2008) Lingjie Fu et al.   BONE

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Adipogenesis and WNT signalling

(2008) Constantinos Christodoulides et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM