Interfacial dilatational deformation accelerates particle formation in monoclonal antibody solutions

Transmission Electron Microscopy as an Orthogonal Method to Characterize Protein Aggregates

(2015) Joyce J. Sung et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Protein Adsorption, Desorption, and Aggregation Mediated by Solid-Liquid Interfaces

(2015) Tatiana Perevozchikova et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Agitation-induced aggregation and subvisible particulate formation in model proteins

(2014) Murali Jayaraman et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Kinetic Analysis of the Multistep Aggregation Mechanism of Monoclonal Antibodies

(2014) Lucrèce Nicoud et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Asphaltene-Laden Interfaces Form Soft Glassy Layers in Contraction Experiments: A Mechanism for Coalescence Blocking

(2014) Vincent Pauchard et al.   LANGMUIR

Do Clustering Monoclonal Antibody Solutions Really Have a Concentration Dependence of Viscosity?

(2013) Jai A. Pathak et al.   BIOPHYSICAL JOURNAL

Understanding the Relationship Between Biotherapeutic Protein Stability and Solid–Liquid Interfacial Shear in Constant Region Mutants of IgG1 and IgG4

(2013) Roumteen Tavakoli-Keshe et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Techniques for monitoring protein misfolding and aggregation in vitro and in living cells

(2012) Simpson Gregoire et al.   KOREAN JOURNAL OF CHEMICAL ENGINEERING

Production of particles of therapeutic proteins at the air–water interface during compression/dilation cycles

(2012) Jared S. Bee et al.   Soft Matter

Classification of Protein Aggregates1

(2011) Linda O. Narhi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Development of a Microflow Digital Imaging Assay to Characterize Protein Particulates During Storage of a High Concentration IgG1 Monoclonal Antibody Formulation

(2010) Klaus Wuchner et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Use of Flow Cytometry for the Detection of Subvisible Particles in Therapeutic Protein Formulations

(2010) Henryk Mach et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Microtensiometer To Probe the Effect of Radius of Curvature on Surfactant Transport to a Spherical Interface

(2010) Nicolas J. Alvarez et al.   LANGMUIR

Response of a concentrated monoclonal antibody formulation to high shear

(2009) Jared S. Bee et al.   BIOTECHNOLOGY AND BIOENGINEERING

Factors influencing antibody stability at solid-liquid interfaces in a high shear environment

(2009) James G. Biddlecombe et al.   BIOTECHNOLOGY PROGRESS

Structural properties of monoclonal antibody aggregates induced by freeze–thawing and thermal stress

(2009) Andrea Hawe et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution

(2009) Renuka Thirumangalathu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A double wall-ring geometry for interfacial shear rheometry

(2009) Steven Vandebril et al.   RHEOLOGICA ACTA

Shaken, Not Stirred: Mechanical Stress Testing of an IgG1 Antibody

(2008) Sylvia Kiese et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Protein aggregation: Pathways, induction factors and analysis

(2008) Hanns-Christian Mahler et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Protein therapeutics: a summary and pharmacological classification

(2007) Benjamin Leader et al.   NATURE REVIEWS DRUG DISCOVERY