Article
Engineering, Electrical & Electronic
Do Thi Thu, Zong-Han Liu, Ya-Chu Lee, Tzu-Wen Kuo, Wei-Lun Sung, Yen-Chang Chu, Yu-Lun Chueh, Weileun Fang
Summary: This study designs and implements a chip-scale amperometric ethanol sensor using the standard commercially available CMOS process and post-CMOS micromachining processes. The sensor consists of a suspended plate with a microhole structure as the working electrode, a fully anchored plate with a microhole structure as the counter electrode, and a microcavity as the electrolyte reservoir. By exploiting the metal and dielectric layers in the CMOS process, the sensor achieves enhanced sensitivity and response time. Measurements show that the sensor has a sensing range of ppm (20-1000 ppm) at room temperature, with a sensitivity of 0.01 nA/ppm and a response time of 6 s. The presented design demonstrates the potential of CMOS-MEMS for amperometric ethanol sensing.
IEEE SENSORS JOURNAL
(2023)
Review
Chemistry, Multidisciplinary
M. Khalid Hossain, S. M. Kamrul Hasan, M. Imran Hossain, Ranjit C. Das, H. Bencherif, M. H. K. Rubel, Md Ferdous Rahman, Tanvir Emrose, Kenichi Hashizume
Summary: This paper discusses the applications of zirconate-based proton-conducting materials in electrochemical cells, focusing on their use in the hydrogen energy field. It provides a comprehensive summary of various doping schemes, experimental setups, operating conditions, and material performance. The challenges hindering the full potential of zirconate materials in electrochemical hydrogen devices are also discussed, and the paper offers suggestions for aspiring researchers in this field.
Article
Engineering, Biomedical
Jennie J. Paik, Boonjae Jang, Sunghyun Nam, L. Jay Guo
Summary: This study presents a physically crosslinked poly(vinyl alcohol) (PVA)-based hydrogel that acts as a transparent strain-sensing skin adhesive for motion monitoring. By incorporating Zn2+ into the ice-templated PVA gel, a dense amorphous structure is observed, allowing the material to stretch up to 800% strain. Fabrication in a binary glycerol:water solvent results in electrical resistance in the k omega range, a gauge factor of 0.84, and ionic conductivity on the scale of 10(-4) S cm(-1), making it a promising low-cost candidate for stretchable electronic materials. The study also investigates the relationship between improved electrical performance and polymer-polymer interactions using spectroscopic techniques.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Analytical
Zinan Zhi, Wanshuo Gao, Jiawei Yang, Chong Geng, Boxuan Yang, Chen Tian, Shurui Fan, Haoyi Li, Jinpo Li, Zhongqiu Hua
Summary: In this study, an amperometric electrochemical hydrogen sensor was developed using solid polymer electrolyte and screen-printed electrodes (SPE). The sensitivity was enhanced by modifying the carbon electrode with a Pt/C/Nafion film. It was shown that the electrochemical behavior of hydrogen and Pt nanoparticles involved single electron transfer in an anaerobic environment and coupling with oxygen in an aerobic environment. A solid amperometric gas sensor was also fabricated using 3D printing, a solid polymer electrolyte, and modified electrodes, resulting in a simple device fabrication process with significantly improved sensitivity.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Electrical & Electronic
Daryl Ma, Sara S. Ghoreishizadeh, Pantelis Georgiou
Summary: This study investigates the feasibility of simultaneous use of potentiometry and amperometry in a single electrochemical cell, showing high correlation in potentiometric readings with a shared reference electrode and good cross correlation in amperometric sensing. Through innovative test systems, the concurrent measurement for potentiometry in the presence of cell current is successfully demonstrated.
IEEE SENSORS JOURNAL
(2021)
Review
Materials Science, Multidisciplinary
D. M. G. Preethichandra, Mahnaz D. Gholami, Emad L. Izake, Anthony P. O'Mullane, Prashant Sonar
Summary: Food spoilage causes significant economic losses, making timely detection of harmful gases crucial for food safety. This review highlights the recent progress of conducting polymer based NH3 and H2S gas sensors and discusses their suitability for developing consumer electronic devices for food spoilage detection.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Physical
Dang Saebea, Amornchai Arpornwichanop, Yaneeporn Patcharavorachot
Summary: This study proposes a power generation system consisting of a steam reformer and SOFC-H+ fueled by different types of fuels like ethanol, glycerol, and biogas. Through thermodynamic calculations and simulations, it is found that glycerol reformate has the highest cell and system efficiencies compared to other fuels in the integrated system.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Chemistry, Physical
Donglin Han, Xin Liu, Tor Svendsen Bjorheim, Tetsuya Uda
Summary: Increasing Ce content in Y-doped BaZrO3, BaCeO3, and their solid solutions stabilizes protons, increases oxide ion conductivity, and decreases hole conduction, thereby enhancing the ionic conduction of BZCY20 for improved performance in fuel cells and electrolysis cells.
ADVANCED ENERGY MATERIALS
(2021)
Article
Chemistry, Physical
Amir Masoud Dayaghi, Reidar Haugsrud, Marit Stange, Yngve Larring, Ragnar Strandbakke, Truls Norby
Summary: Proton conducting oxide electrolytes with increased thermal expansion coefficient by partially substituting Ba and Zr with Sr and Ce while maintaining a cubic structure and minor n-type conduction, have potential applications in proton ceramic electrochemical cells at intermediate temperatures.
SOLID STATE IONICS
(2021)
Article
Chemistry, Physical
M. Anandha Jothi, D. Vanitha, S. Asath Bahadur, N. Nallamuthu
Summary: Proton conducting polymer blend electrolytes based on cornstarch and PVP with NH4Br were prepared by solution casting technique. The addition of NH4Br enhanced the amorphous nature of the blend confirmed by XRD, and caused changes in peak intensity, peak shape, and position in FTIR, indicating complex formation between the polymer and salt. The highest conductivity was observed in the 30 wt.% NH4Br added system at 358 K. The conduction mechanism involves quantum mechanical tunneling at mid-frequency and large polaron tunneling at higher frequency.
Article
Materials Science, Multidisciplinary
Kevin Ton, Asia Vighi, Keryn Lian, Ta-Ya Chu, Ye Tao
Summary: The phosphoric acid-polyvinyl alcohol electrolyte has been demonstrated as an effective gate dielectric for electrolyte-gated field-effect transistors, showing high performance with sub 1 V operation, high ON/OFF ratio >10^5, and low subthreshold swing of 90 mV/decade. This indicates the strong potential of proton conducting polymer electrolytes as gate dielectrics for low-power EGFET devices.
ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY
(2021)
Article
Polymer Science
Kei Ohori, Kazuto Hatakeyama, Michio Koinuma, Shintaro Ida
Summary: An all-solid-state supercapacitor without boundary between electrode/electrolyte interface is prepared using MSA-intercalated GO membranes as a proton-conducting electrolyte. The capacitor shows a large capacitance and improved cycle stability due to the seamless structures and high proton conductivity.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Materials Science, Multidisciplinary
Omed Gh Abdullah, Hawzhin T. Ahmed, Dana A. Tahir, Gelas M. Jamal, Azhin H. Mohamad
Summary: This study improved the ionic conductivity of polymer electrolytes by incorporating polyethylene glycol (PEG) plasticizer in different stoichiometric ratios. The resistance of the electrolyte decreased with increasing temperature, and the frequency- and temperature-dependence of conductivity followed specific relation models. Through specific model analysis, the plasticized samples exhibited higher ionic conductivity and shorter dielectric relaxation time.
RESULTS IN PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Inna A. Starostina, George N. Starostin, Mariam T. Akopian, Gennady K. Vdovin, Denis A. Osinkin, Baptiste Py, Adeleke Maradesa, Francesco Ciucci, Dmitry A. Medvedev
Summary: The low-temperature transport properties of BaSn0.8Y0.2O3-delta, a representative of proton-conducting materials, were investigated. The study focused on the grain and grain boundary conductivity of this ceramic material under various experimental conditions. Electrochemical impedance spectroscopy was used to analyze the electrolytic processes and evaluate the resistance, capacitance, and frequency. The results showed that the BSY ceramic prepared with CuO as a sintering additive exhibited three distinct processes related to grain response and the responses of pure and CuO-covered grain boundaries.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Somayeh Tajik, Zahra Dourandish, Peyman Mohammadzadeh Jahani, Iran Sheikhshoaie, Hadi Beitollahi, Mehdi Shahedi Asl, Ho Won Jang, Mohammadreza Shokouhimehr
Summary: This review article provides an overview of recent advances in voltammetric and amperometric sensing of cysteine (Cys), discussing its important role as an essential amino acid, sensing techniques, and utilization of electrochemical methods. The main focus is on the use of various electrocatalytic materials to modify electrodes for voltammetric and amperometric sensing of Cys. The conclusion highlights current challenges in Cys determination and future perspectives.
Article
Chemistry, Multidisciplinary
Anna V. Shlyakhtina, Nikolay V. Lyskov, Galina E. Nikiforova, Anna V. Kasyanova, Galina A. Vorobieva, Igor V. Kolbanev, Dmitry N. Stolbov, Dmitry A. Medvedev
Summary: The design of new oxygen- and proton-conducting materials is crucial for their potential application in solid oxide fuel cells. In this study, La-2(Hf2-xLax)O7-x/2 ceramics were prepared and investigated for their conductivity properties. It was found that La-2(Hf1.9La0.1)O-6.95 stuffed pyrochlore ceramics exhibited both oxygen ion and proton conductivities.
APPLIED SCIENCES-BASEL
(2022)
Review
Chemistry, Multidisciplinary
Elena Filonova, Dmitry Medvedev
Summary: This review summarizes two representative families of oxygen-conducting electrolytes: doped lanthanum aluminates (LaAlO3) and lanthanum gallates (LaGaO3). Their preparation features, chemical stability, thermal behaviour and transport properties are thoroughly analyzed in terms of their connection with the target functional parameters of related solid oxide fuel cells (SOFCs).
Article
Materials Science, Ceramics
Inna A. Zvonareva, Alexey M. Mineev, Natalia A. Tarasova, Xian-Zhu Fu, Dmitry A. Medvedev
Summary: This study investigates the transport properties of scandium-doped barium stannate and finds that the Sc doping can improve the ionic conductivity, making the material suitable for PCFC applications even under reducing conditions.
JOURNAL OF ADVANCED CERAMICS
(2022)
Article
Materials Science, Ceramics
George N. Starostin, Inna A. Zvonareva, Dmitry A. Medvedev, Sergey Zvonarev
Summary: This study synthesized ZnAl2O4-based ceramic materials through two different synthesis methods and investigated their luminescent properties depending on morphology. The results showed that ceramic samples obtained using the solid-state synthesis method were more defective in morphology and exhibited higher thermoluminescence sensitivity. The optimal samples exhibited a linear thermoluminescence dependence over a wide absorbed dose range, indicating their potential as ionizing irradiation detectors.
CERAMICS INTERNATIONAL
(2022)
Review
Materials Science, Ceramics
Inna A. Zvonareva, Dmitry A. Medvedev
Summary: Solid oxide fuel cells are efficient energy conversion devices, but the traditional yttria-stabilized zirconia materials used for electrolytes require high temperatures. This study analyzes the potential of barium stannate as a proton-conducting electrolyte material and confirms its suitability.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2023)
Article
Electrochemistry
Anna V. Kasyanova, Julia G. Lyagaeva, Gennady K. Vdovin, Anna A. Murashkina, Dmitry A. Medvedev
Summary: The synthesis and comprehensive study of acceptor-doped lanthanum ytterbates were successfully conducted. These materials showed high chemical stability, good conductivity, and promising proton-conducting properties, making them suitable for various electrochemical devices, such as solid oxide fuel cells.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Physical
Artem P. Tarutin, Nikolai A. Danilov, Andrey A. Kalinin, Anna A. Murashkina, Dmitry A. Medvedev
Summary: The thermomechanical and chemical properties of Pr2NiO4+a-based electrode materials were optimized via Ba-doping, reducing their chemical interaction with Ba(Ce,Zr)O3-based electrolytes.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Chemistry, Physical
Anatoly Kalyakin, Anatoly K. K. Demin, Elena Gorbova, Alexander Volkov, Panagiotis E. E. Tsiakaras
Summary: This study describes the performance and assessment of a sensor based on a solid oxide electrolyte for measuring water vapor and hydrogen content in air. The sensor, equipped with a ceramic diffusion barrier, operates successfully at 700°C and can be used for continuous determination of the concentrations of water vapor and hydrogen in air. A two-stage method is proposed to determine the amount of hydrogen and steam in the ambient air.
Article
Chemistry, Physical
Yuanyan Luo, Wenhua Lou, Huiyan Feng, Zhihang Liu, Qiuyan Chen, Guizhen Liao, Xiaoting Huang, Panagiotis Tsiakaras, Peikang Shen
Summary: Ultra-small Pt-based catalysts were synthesized by a Pd seed-inducing-growth route, showing specific effects for enhancing the oxygen reduction reaction (ORR) and improving Pt utilization.
Review
Chemistry, Physical
Elena Gorbova, Georgia Balkourani, Costas Molochas, Dimitrios Sidiropoulos, Angeliki Brouzgou, Anatoly Demin, Panagiotis Tsiakaras
Summary: Hydrogen sensors, especially those operating at high temperatures, are crucial for the safe and widespread use of hydrogen as fuel in the emerging hydrogen economy. This review focuses on hydrogen sensors based on solid oxide electrolytes and discusses their configuration, principle of operation, and application.
Review
Biochemistry & Molecular Biology
Syed Shoaib Ahmad Shah, Naseem Ahmad Khan, Muhammad Imran, Muhammad Rashid, Muhammad Khurram Tufail, Aziz ur Rehman, Georgia Balkourani, Manzar Sohail, Tayyaba Najam, Panagiotis Tsiakaras
Summary: The hydrogen evolution reaction (HER) is a promising technology for delivering clean energy using renewable sources. The use of transition metal tellurides (TMTs) and transition metal phosphides (TMPs) as electrocatalysts has emerged as a highly efficient, low-cost, and stable alternative to platinum-based catalysts. This review focuses on the progress made in the past decade, providing a detailed summary of their development and offering guidelines for the design of new electrocatalysts for energy conversion and storage technologies.
Article
Chemistry, Physical
Inna A. Zvonareva, George N. Starostin, Mariam T. Akopian, Gennady K. Vdovin, Xian-Zhu Fu, Dmitry A. Medvedev
Summary: The search for new oxide materials with pronounced proton transport is important for efficient energy conversion processes. Y-doped barium stannates exhibit varying transport properties depending on the doping degree, with weakly doped stannates being electron conductors and heavily doped stannates showing higher ionic conductivity and wider electrolytic domain boundary, making them potential electrolytes for protonic ceramic fuel and electrolysis cells.
JOURNAL OF POWER SOURCES
(2023)
Article
Chemistry, Inorganic & Nuclear
Ksenia Belova, Anastasia Egorova, Svetlana Pachina, Irina Animitsa, Dmitry Medvedev
Summary: Oxygen-ionic and proton-conducting oxides, including La2ZnNdO5.5 and its Ca-doped derivatives, were synthesized. These materials were characterized for their phase composition, lattice parameters, and hydration capability. The conductivities of the samples were measured in dry and wet air, showing a significant increase in conductivity due to oxygen vacancies during acceptor doping. The Ca-doped phases also exhibited proton-conducting properties.
Article
Materials Science, Ceramics
Inna A. Zvonareva, George N. Starostin, Mariam T. Akopian, Anna A. Murashkina, Xian-Zhu Fu, Dmitry A. Medvedev
Summary: BaSnO3 is a new family of proton-conducting materials with potential high-temperature applications. The synthesis and characterization of BaSn1-xYxO3-δ (0 < x < 0.4) phases were conducted to understand the variations of chemical and thermal strains depending on composition. The results show that the importance of chemical expansion/contraction effects increases with increasing Y-content. These findings provide valuable data for the application of these materials in protonic ceramic devices.
CERAMICS INTERNATIONAL
(2023)
Review
Chemistry, Physical
Nikolai A. Danilov, Inna A. Starostina, George N. Starostin, Anna V. Kasyanova, Dmitry A. Medvedev, Zongping Shao
Summary: Proton-conducting oxide materials have protonic defects in their crystal structure due to their interaction with hydrogen-containing atmospheres, resulting in superior ionic conductivity. Barium cerate, barium zirconate, and barium cerate-zirconate are widely studied as proton-conducting electrolyte materials. Y and Yb co-doped Ba(Ce,Zr)O-3 is considered one of the most promising systems.
ADVANCED ENERGY MATERIALS
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)