Article
Chemistry, Multidisciplinary
Meng Zhang, Youdi Hu, Shuaiqi Wang, Yaru Li, Chunwu Wang, Ke Meng, Gang Chen
Summary: A new device architecture for self-driven photodetectors with tunable asymmetric Schottky junctions based on a nanomesh electrode is reported. The optimized device demonstrates high detectivity and a large on/off ratio, showing promise for various applications requiring self-driven photodetectors. The nanomesh electrode can also be used to investigate the optoelectronic properties of different semiconducting materials.
Article
Chemistry, Analytical
Zixuan Wu, Jianxun Liu, Zhenming Wang, Lei Chen, Yiwei Xu, Zongjun Ma, Delai Kong, Dan Luo, Yan Jun Liu
Summary: We demonstrated a low-cost, highly sensitive hybrid Ag-Cu substrate with enhanced absorption for the excitation laser beam via the nanosphere lithography technique. The substrate consists of a Cu nanoarray covered with Ag nanoparticles, resulting in optimized absorption for the laser beam. Raman enhancement is achieved by incorporating plasmonic hotspots formed by dense Ag nanoparticles. The hybrid Ag-Cu SERS substrates exhibit a highly sensitive and reproducible SERS activity, with potential applications in biosensors, environmental monitoring, and food safety.
Article
Chemistry, Analytical
Shaoxiong Wu, Cheng Chen, Xihang Wu, Feng Tian, Yungui Ma, Yang Xu, Huan Hu
Summary: A scalable nanofabrication approach is reported in this study for the fabrication of hexagonal packed complementary vertically coupled plasmonic (CVCP) structures for surface-enhanced infrared absorption (SEIRA) applications. The CVCP structure contains dense plasmonic nanoparticles inside a three-dimensional cavity nanoantenna array, generating a solid localized electric field inside the cavity. By optimizing the height of the silicon nanopedestals, a high SEIRA electric-field enhancement was achieved, with an enhancement factor of 2.1 x 103 demonstrated using a representative monolayer octadecanethiol on the optimized structure geometry. When the detection area was extended to square millimeters, the limit of detection of monolayer octadecanethiol on the CVCP substrate reached 10 nM, four orders of magnitude lower than that on a flat gold substrate. This study demonstrates a feasible fabrication approach for producing three-dimensional nanoantenna structures with high enhancement factors in a scalable fashion, enabling the practical application of SEIRA substrates.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Nanoscience & Nanotechnology
Dong Su, Siqi Yang, Yuxuan Xiong, Xi Yang, Xie Yu, Pei Zeng, Yuqing Wu, Yutian Cheng, Tao Zhang, Haiping Shen, Huageng Liang, Guangzu Zhang, Boxiang Song, Shenglin Jiang
Summary: Surface-enhanced Raman spectroscopy (SERS) is a powerful technique for ultrasensitive molecular detection. In this study, hierarchical plasmonic hotspot arrays consisting of ordered Au nanoclusters were proposed for large-scale SERS substrates with high enhancement and uniform response. The fabrication process involved modified colloidal lithography with rotational coordinates, which induced nanogaps formation in the Au nanoclusters. The plasmonic coupling in these nanogaps resulted in an ultrahigh Raman enhancement factor and low limit of detection. This hierarchical plasmonic hotspot array showed high uniformity and sensitivity, and was able to accurately identify the components in transformer oil, making it a promising platform for ultrasensitive molecular detection.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Daniela Lospinoso, Adriano Colombelli, Mauro Lomascolo, Roberto Rella, Maria Grazia Manera
Summary: Arrays of metal nano-holes have great potential for applications in nano-photonics and optoelectronics. By adjusting the size and composition of the holes, the electromagnetic field distribution can be modulated, leading to hotspot excitations and enhancing Raman spectroscopy.
Article
Nanoscience & Nanotechnology
Sunil Mehla, Ahmad Kandjani, Victoria Coyle, Christopher J. Harrison, Mei Xian Low, Richard B. Kaner, Ylias Sabri, Suresh K. Bhargava
Summary: A facile method is presented for selectively growing dendritic gold nanostructures on the lateral surfaces of conductor-dielectric disc arrays, resulting in the fabrication of gold sunflower microelectrode arrays (SMA). The SMA exhibits broadband antireflection characteristics, tunable photonic-plasmonic hybrid modes, strong electromagnetic field enhancements, and a high density of electromagnetic hotspots useful for surface-enhanced Raman scattering (SERS) detection.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Dirk Doehler, Andres Triana, Pascal Buettner, Florian Scheler, Eric S. A. Goerlitzer, Johannes Harrer, Anna Vasileva, Ezzeldin Metwalli, Wolfgang Gruber, Tobias Unruh, Alina Manshina, Nicolas Vogel, Julien Bachmann, Ignacio Minguez-Bacho
Summary: A highly ordered nanostructured transparent electrode is prepared via a combination of nanosphere lithography and anodization, improving pore domain size and reducing defect pore density. The increased electrical contact between the electrode and the conductive substrate results in improved performance of energy conversion devices.
Article
Materials Science, Characterization & Testing
Akarapan Rojjanapinun, Sheree A. Pagsuyoin, Jason Perman, Hongwei Sun
Summary: This work presents an improved route for developing low-cost and robust isoporous polyvinylidene fluoride (PVDF) nanomembranes for industrial separation and purification processes. The membranes exhibit high rejection rates for various substances and maintain high tensile strength due to improved routes to beta crystalline formations.
Article
Physics, Condensed Matter
Stavros Panos, Despina Tselekidou, Spyros Kassavetis, Ilias Fekas, John Arvanitidis, Dimitris Christofilos, Dimitrios Karfaridis, Spilios Dellis, Stergios Logothetidis, Panos Patsalas
Summary: By optimizing the process parameters of nanosphere lithography and reactive magnetron sputtering, well-defined TiN nanoislands with low concentration of point defects were successfully grown.
PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS
(2021)
Review
Biochemistry & Molecular Biology
Gregory Barbillon
Summary: Metasurfaces have the ability to confine electromagnetic fields on large surfaces and zones, making them suitable for applications in biochemical sensing, photocatalysis, etc. They enhance the effects of SERS and SEIRA sensing by the presence of hotspots and confined optical modes within their structures, as well as by supporting resonances at frequencies of the excitation and emission processes. Additionally, Metasurfaces enhance the absorption capacity of solar light and generate more catalytic active sites for faster surface reactions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemical Research Methods
Kessia Nattaly Oliveira dos Santos, Monica Benicia Mamian-Lopez
Summary: Optical sensors can detect various substances, from biological samples to hazardous substances. In this study, a colorimetric nanoantenna sensor using gold nanoparticles embedded in poly(vinyl alcohol) and decorated with a dye was constructed. The sensor demonstrated potential reusability and was used to visually detect H2O2 with a smartphone-based app. Chemometric modeling of the app data allowed for a detection limit of 0.0058% of H2O2 and visual observation of sensor changes, supporting the combination of nanoantenna sensors with chemometric tools for sensor design. This approach has the potential to enable visual detection and colorimetric quantification of analytes in complex samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Jeremy J. Baumberg
Summary: This article introduces the discovery and significance of sub-nanometer-scale optical cavities. We develop simple models for these picocavities and discuss what is known and unknown in this field, as well as the challenges faced in developing comprehensive theories. We also provide simple analytic expressions for key properties and discuss the importance of picocavities in various applications.
Article
Materials Science, Multidisciplinary
Zhen Yin, Kaichen Xu, Shouzhen Jiang, Dan Luo, Rui Chen, Chunxiang Xu, Ping Shum, Yan Jun Liu
Summary: This article summarizes the recent progress of 2D materials-based SERS technology as a complement to plasmonic SERS substrates. Symmetry of lattice structure, isotropic and anisotropic 2D materials for SERS, and various methods to improve SERS performance are discussed. Sensitivity, limit of detection, and stability of 2D materials-based heterostructures as SERS platforms are also addressed, along with applications in niche areas such as local strain probing, remote/in-situ chemical analysis, and fine structure characterization.
MATERIALS TODAY PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Gai Zhang, Le Chang, Hua Shao, Chunshuang Chu, Chao Fan, Yandi Zhang, Yonghui Zhang, Zi-Hui Zhang
Summary: In this study, an ultra-thin air cavity nanopatterned sapphire substrate (UTAC-NPSS) is fabricated using a combination of nanosphere lens lithography, atomic layer deposition (ALD), and partial exposure lithography. The UTAC-NPSS improves the crystalline quality and light extraction efficiency (LEE) of GaN-based near-ultraviolet light-emitting diodes (NUV LEDs).
Article
Chemistry, Physical
Yanan Song, Jingyi Sun, Shijun Zhao, Feng Gao, Hui Yuan, Baoliang Sun, Baojun Wang, Ying Wang
Summary: A method using surface-enhanced Raman scattering (SERS) active nanospheres combined with probe-immobilized lateral flow strip was developed to assess multiple biomarkers in blood samples of stroke patients. The method demonstrated sensitive and quantitative measures towards stroke-related MMP-9, S00-beta, and NSE, showing potential for reliable stroke diagnosis and prognosis evaluation in clinical applications. The accuracy of SERS imaging was confirmed by enzyme linked immunosorbent assay (ELISA), indicating the feasibility of this method for further quantitative analysis of molecules in blood samples.
APPLIED SURFACE SCIENCE
(2022)
Editorial Material
Optics
Gregory Barbillon
Article
Physics, Applied
Andrey K. Sarychev, Andrey Ivanov, Andrey N. Lagarkov, Ilya Ryzhikov, Konstantin Afanasev, Igor Bykov, Gregory Barbillon, Nikita Bakholdin, Mikhail Mikhailov, Alexander Smyk, Alexander Shurygin, Alexander Shalygin
Summary: This study presents the design and fabrication of metal-dielectric metasurfaces, as well as their application in the excitation of plasmons and surface-enhanced Raman scattering. By utilizing the periodic arrangement of metal nanogratings on a dielectric substrate, an open plasmon resonator is formed, leading to the enhancement of the local electromagnetic field at optical frequencies.
PHYSICAL REVIEW APPLIED
(2022)
Article
Physics, Applied
Jeremy Bonhomme, Mourad Oudich, Mohamed Lamine Faycal Bellaredj, Jean-Francois Bryche, Pedro Alberto Segura Chavez, Denis Beyssen, Paul G. Charette, Frederic Sarry
Summary: The interaction of Love waves with micropillars on the guiding layer surface produces sharp attenuation dips in the transmission spectrum, utilizing the local resonances of the micropillars. These dips are associated with the excitations of flexural and torsional resonance modes of the pillars, enabling higher detection sensitivity for temperature variations and mass loading.
PHYSICAL REVIEW APPLIED
(2022)
Article
Optics
Gregory Barbillon
Summary: This study presents a research on the sensing of chemical molecules using Au nanoparticles coated ZnO film by employing the photo-induced enhanced Raman scattering (PIERS) coupled to the surface-enhanced Raman scattering (SERS). The aim of coupling the PIERS to classical SERS is to achieve high sensitivity of detection. The detection of thiophenol showed a limit concentration of 100 pM, an adsorption capacity (K-Ads) of 3.2 x 10(6) M-1 and an analytical enhancement factor of 1.9 x 10(10).
Article
Biophysics
Zhor Khadir, Victor Schmidt, Kevin Chabot, Jean-Francois Bryche, Ulrike Froehlich, Julien Moreau, Michael Canva, Paul Charette, Michel Grandbois
Summary: This study utilizes surface micropatterning techniques to control the adhesion of endothelial cells and establish a well-controlled cell layer phenotype on SPR sensor surfaces. The formation of cell-cell junctions can be controlled by tuning the inter-cellular spacing. The functionality of the proposed model has been confirmed through fluorescence microscopy and SPRI.
BIOSENSORS & BIOELECTRONICS
(2022)
Review
Biochemistry & Molecular Biology
Gregory Barbillon
Summary: Metasurfaces have the ability to confine electromagnetic fields on large surfaces and zones, making them suitable for applications in biochemical sensing, photocatalysis, etc. They enhance the effects of SERS and SEIRA sensing by the presence of hotspots and confined optical modes within their structures, as well as by supporting resonances at frequencies of the excitation and emission processes. Additionally, Metasurfaces enhance the absorption capacity of solar light and generate more catalytic active sites for faster surface reactions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Jean-Francois Bryche, Marlo Vega, Agnes Tempez, Thibault Brule, Thomas Carlier, Julien Moreau, Marc Chaigneau, Paul G. Charette, Michael Canva
Summary: This work demonstrates the enhancement in plasmonic sensing efficacy by spatially-localized functionalization on nanostructured surfaces, where probe molecules are concentrated in areas of high field concentration. SERS measurements on nanostructured surfaces with homogeneous and spatially-localized functionalization with thiophenol show that the Raman signal mainly originates from high field concentration areas. TERS measurements with 10 nm spatial resolution confirm the predicted field distribution profiles.
Article
Chemistry, Multidisciplinary
Gregory Barbillon, Christophe Humbert, Maria Ujue Gonzalez, Jose Miguel Garcia-Martin
Summary: In this study, we investigated chemical sensing using surface-enhanced Raman scattering with gold nanocolumn templates. The glancing angle deposition with magnetron sputtering technique was chosen for its low-cost production and ease of implementation. The fabricated gold nanocolumnar structures allowed for the production of a high density of strongly confined electric field spots. The vertical and tilted nanocolumnar templates showed promising results for the detection and adsorption of thiophenol molecules.
Article
Engineering, Electrical & Electronic
P. Girault, L. Oyhenart, T. Rouanet, S. Joly, G. Beaudin, M. Canva, L. Bechou, P. G. Charette
Summary: This work presents a detailed modeling-based analysis of integrated micro-ring resonators used for absorption spectroscopy. Typically, sensors based on micro-ring resonators detect changes in the real part of the refractive index of the sensing medium at critical coupling. However, in absorption spectroscopy, micro-ring resonators are used to measure changes in the imaginary part of the index and are most sensitive away from critical coupling, with separate maxima in the under- and over-coupled regimes. The analysis in this work focuses on the under-coupled regime, exploring the relationships between sensitivity, mode confinement, and losses.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Jean-Francois Bryche, Marlo Vega, Julien Moreau, Paul-Ludovic Karsenti, Paul Bresson, Mondher Besbes, Philippe Gogol, Denis Morris, Paul G. Charette, Michael Canva
Summary: Thermoplasmonics has gained increasing attention for generating nanoscale heat sources using photothermal effects in plasmonic nanoparticles. By exciting gold nanoparticles with ultrashort light pulses, high-speed light management and nanoscale heat-sensitive chemical reaction control can be achieved. This study investigates the non-uniform thermal energy distribution in cross-shaped nanostructures using femtosecond transient spectroscopy and a thermooptical numerical model. The results show that the polarization of the excitation light can control heat distribution in the nanostructures, and nonthermal electron ballistic displacement is crucial in fast transient heat dynamics models.
Article
Chemistry, Analytical
M. Vega, J. -F. Bryche, P. -L. Karsenti, P. Gogol, M. Canva, P. G. Charette
Summary: This paper proposes a 2D method for removing coherent artifacts from femtosecond time-resolved spectroscopy data, which is simple, intuitive, and light on computation resources. The effectiveness of the method is demonstrated with experimental data, and it is expected to be applicable to other types of time and wavelength-resolved spectroscopy data.
ANALYTICA CHIMICA ACTA
(2023)
Review
Physics, Applied
Alemayehu Nana Koya, Marco Romanelli, Joel Kuttruff, Nils Henriksson, Andrei Stefancu, Gustavo Grinblat, Aitor De Andres, Fritz Schnur, Mirko Vanzan, Margherita Marsili, Mahfujur Rahaman, Alba Viejo Rodriguez, Tlek Tapani, Haifeng Lin, Bereket Dalga Dana, Jingquan Lin, Gregory Barbillon, Remo Proietti Zaccaria, Daniele Brida, Deep Jariwala, Laszlo Veisz, Emiliano Cortes, Stefano Corni, Denis Garoli, Nicolo Maccaferri
Summary: In the past twenty years, significant progress has been made in understanding light-driven phenomena in nanoscale systems, while exploring the temporal dynamics of excited states remains a challenge. Ultrafast plasmonics, which focuses on tailoring and controlling optical and electronic processes at the nanoscale, offers great potential for applications such as optical switching and photochemical reactions. This review provides an overview of the field, discussing methodologies for monitoring and controlling nanoscale phenomena with plasmons, and highlighting recent advances in plasmon-driven chemistry and multifunctional plasmonics.
APPLIED PHYSICS REVIEWS
(2023)
Article
Chemistry, Physical
Gregory Barbillon
Summary: This study investigates the Fermi level shifts of gold nanospheres on zinc oxide (ZnO) film upon UV irradiation. The shifts are obtained by recording the extinction spectra of gold nanospheres and are attributed to the additional electrons stored in the nanospheres from ZnO film. The blueshift of plasmon resonance of the Au nanospheres indicates the transfer of electrons from ZnO film to Au nanospheres upon UV irradiation. The Fermi level shifts vary with UV irradiation time and can be estimated by a model based on the electronic structure of a semiconductor.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Andrey K. Sarychev, Gregory Barbillon, Andrey Ivanov
Summary: This study presents generic, analytical equations for the localized plasmons in a narrow gap between a metal/dielectric cylinder and a metal surface. The electric field distribution in the nanogap is obtained using the quasi-static approximation. The maximum electric field is achieved when the incident light is in resonance with the plasmon mode in the gap, and can be significantly enhanced. The analytical model results are in good agreement with a known theoretical model and experimental results of surface-enhanced Raman scattering (SERS). The narrow gap resonator appears to be a powerful and flexible tool for various spectroscopies such as SERS and infrared absorption.
APPLIED SCIENCES-BASEL
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
