期刊
SEMINARS IN FETAL & NEONATAL MEDICINE
卷 21, 期 6, 页码 380-387出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.siny.2016.04.004
关键词
Gut microbiota; Immune system; Metabolism; Diet; Antibiotics; Cesarean section
类别
资金
- NICHD NIH HHS [R01 HD061929] Funding Source: Medline
Microbial colonization of the infant intestine occurs in the first two years of life. Symbiotic host and microbe interactions are critical for host metabolic and immune development. Emerging evidence indicates that early microbiota colonization may influence the occurrence of metabolic and immune diseases. Further understanding of the importance of environmental factors, including fetal microbial exposure, diet, delivery mode, pre- and probiotic consumption, and antibiotic use on immune and metabolic programming will provide new opportunities for the development of therapeutic and prophylactic measures to improve infant health and reduce the risk of disease in post -infancy years. (C) 2016 Elsevier Ltd. All rights reserved.
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