Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome
出版年份 2016 全文链接
标题
Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome
作者
关键词
-
出版物
Science Translational Medicine
Volume 8, Issue 338, Pages 338ra67-338ra67
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2016-05-12
DOI
10.1126/scitranslmed.aaf3006
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Coordinate expression of heme and globin is essential for effective erythropoiesis
- (2015) Raymond T. Doty et al. JOURNAL OF CLINICAL INVESTIGATION
- Disruption of the 5S RNP–Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia
- (2015) P Jaako et al. LEUKEMIA
- Ferroptosis as a p53-mediated activity during tumour suppression
- (2015) Le Jiang et al. NATURE
- Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis
- (2015) Lucia Morgado-Palacin et al. Cell Reports
- Nucleolar stress in Diamond Blackfan anemia pathophysiology
- (2014) Steven R. Ellis BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Isolation and transcriptome analyses of human erythroid progenitors: BFU-E and CFU-E
- (2014) J. Li et al. BLOOD
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Translational control by heme-regulated eIF2α kinase during erythropoiesis
- (2014) Jane-Jane Chen CURRENT OPINION IN HEMATOLOGY
- Adequate iron chelation therapy for at least six months improves survival in transfusion-dependent patients with lower risk myelodysplastic syndromes
- (2014) Michel Delforge et al. LEUKEMIA RESEARCH
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Altered translation of GATA1 in Diamond-Blackfan anemia
- (2014) Leif S Ludwig et al. NATURE MEDICINE
- Wearing Red for Signaling: The Heme-Bach Axis in Heme Metabolism, Oxidative Stress Response and Iron Immunology
- (2014) Kazuhiko Igarashi et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Isolation and functional characterization of human erythroblasts at distinct stages: implications for understanding of normal and disordered erythropoiesis in vivo
- (2013) J. Hu et al. BLOOD
- Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond–Blackfan anemia
- (2013) Michael Landowski et al. HUMAN GENETICS
- Erythroid Heme Biosynthesis and Its Disorders
- (2013) H. A. Dailey et al. Cold Spring Harbor Perspectives in Medicine
- Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia
- (2012) Rastislav Horos et al. BRITISH JOURNAL OF HAEMATOLOGY
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Deferasirox Reduces Serum Ferritin and Labile Plasma Iron in RBC Transfusion–Dependent Patients With Myelodysplastic Syndrome
- (2012) Alan F. List et al. JOURNAL OF CLINICAL ONCOLOGY
- Iron overload impairs proliferation of erythroid progenitors cells (BFU-E) from patients with myelodysplastic syndromes
- (2012) Julia Hartmann et al. LEUKEMIA RESEARCH
- Lenalidomide promotes p53 degradation by inhibiting MDM2 auto-ubiquitination in myelodysplastic syndrome with chromosome 5q deletion
- (2012) S Wei et al. ONCOGENE
- Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome
- (2011) K. A. McGowan et al. BLOOD
- Dexamethasone and lenalidomide have distinct functional effects on erythropoiesis
- (2011) A. Narla et al. BLOOD
- Proof of principle for transfusion of in vitro-generated red blood cells
- (2011) M.-C. Giarratana et al. BLOOD
- Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts
- (2011) R. Horos et al. BLOOD
- Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia
- (2011) P. Jaako et al. BLOOD
- Establishing Rps6 hemizygous mice as a model for studying how ribosomal protein haploinsufficiency impairs erythropoiesis
- (2011) Siobán B. Keel et al. EXPERIMENTAL HEMATOLOGY
- The BTB and CNC Homology 1 (BACH1) Target Genes Are Involved in the Oxidative Stress Response and in Control of the Cell Cycle
- (2011) Hans-Jörg Warnatz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Animal Models of Diamond Blackfan Anemia
- (2011) Kelly A. McGowan et al. SEMINARS IN HEMATOLOGY
- Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells
- (2010) S. Dutt et al. BLOOD
- Two to Tango: Regulation of Mammalian Iron Metabolism
- (2010) Matthias W. Hentze et al. CELL
- Kinetics and Specificity of Feline Leukemia Virus Subgroup C Receptor (FLVCR) Export Function and Its Dependence on Hemopexin
- (2010) Zhantao Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction
- (2009) Stefano Fumagalli et al. NATURE CELL BIOLOGY
- A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q– syndrome
- (2009) Jillian L Barlow et al. NATURE MEDICINE
- Oxidative Stress in the Regulation of Normal and Neoplastic Hematopoiesis
- (2008) Saghi Ghaffari ANTIOXIDANTS & REDOX SIGNALING
- Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis
- (2008) M. A. Rey et al. HAEMATOLOGICA
- Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
- (2008) Benjamin L. Ebert et al. NATURE
- A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis
- (2008) S. B. Keel et al. SCIENCE
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