An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron

Systematic discovery of cap-independent translation sequences in human and viral genomes

(2016) Shira Weingarten-Gabbay et al.   SCIENCE

Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects

(2016) Xiaojin Zhang et al.   Nature Communications

Pumilio1 Haploinsufficiency Leads to SCA1-like Neurodegeneration by Increasing Wild-Type Ataxin1 Levels

(2015) Vincenzo A. Gennarino et al.   CELL

An internal ribosome entry site in the 5′ untranslated region of epidermal growth factor receptor allows hypoxic expression

(2015) T E Webb et al.   Oncogenesis

A tool for design of primers for microRNA-specific quantitative RT-qPCR

(2014) Peter K Busk   BMC BIOINFORMATICS

MicroRNAs Block Assembly of eIF4F Translation Initiation Complex in Drosophila

(2014) Takashi Fukaya et al.   MOLECULAR CELL

MicroRNAs Trigger Dissociation of eIF4AI and eIF4AII from Target mRNAs in Humans

(2014) Akira Fukao et al.   MOLECULAR CELL

Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage

(2014) Judith Hauptmann et al.   RNA

A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1

(2014) B. P. Tsai et al.   Open Biology

Second Cistron in CACNA1A Gene Encodes a Transcription Factor Mediating Cerebellar Development and SCA6

(2013) Xiaofei Du et al.   CELL

The translation initiation factor DAP5 promotes IRES-driven translation of p53 mRNA

(2013) S Weingarten-Gabbay et al.   ONCOGENE

Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7

(2013) Udo Rüb et al.   PROGRESS IN NEUROBIOLOGY

Translational Repression and eIF4A2 Activity Are Critical for MicroRNA-Mediated Gene Regulation

(2013) H. A. Meijer et al.   SCIENCE

Systemic Delivery of Tyrosine-Mutant AAV Vectors Results in Robust Transduction of Neurons in Adult Mice

(2013) Asako Iida et al.   Biomed Research International

Brain pathology of spinocerebellar ataxias

(2012) Kay Seidel et al.   ACTA NEUROPATHOLOGICA

RNA-Based Therapeutics: Current Progress and Future Prospects

(2012) John C. Burnett et al.   CHEMISTRY & BIOLOGY

Developing MicroRNA Therapeutics

(2012) Eva van Rooij et al.   CIRCULATION RESEARCH

Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain

(2012) Shuo Gu et al.   CURRENT BIOLOGY

miRNA_Targets: A database for miRNA target predictions in coding and non-coding regions of mRNAs

(2012) Amit Kumar et al.   GENOMICS

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2

(2012) Yu Miyazaki et al.   NATURE MEDICINE

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

(2012) Ryszard Kole et al.   NATURE REVIEWS DRUG DISCOVERY

Expression determinants of mammalian argonaute proteins in mediating gene silencing

(2012) Paul N. Valdmanis et al.   NUCLEIC ACIDS RESEARCH

Argonaute identity defines the length of mature mammalian microRNAs

(2012) Prasanna Kumar Juvvuna et al.   NUCLEIC ACIDS RESEARCH

siRNA Has Greatly Elevated Mismatch Tolerance at 3′-UTR Sites

(2012) Na Wei et al.   PLoS One

Translational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granules

(2011) Khosrow Adeli   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA Replacement Therapy for miR-145 and miR-33a Is Efficacious in a Model of Colon Carcinoma

(2011) A. F. Ibrahim et al.   CANCER RESEARCH

Current prospects for RNA interference-based therapies

(2011) Beverly L. Davidson et al.   NATURE REVIEWS GENETICS

Development of an anatomical technique for visualizing the mode of climbing fiber innervation in Purkinje cells and its application to mutant mice lacking GluRδ2 and Cav2.1

(2010) Taisuke Miyazaki et al.   ANATOMICAL SCIENCE INTERNATIONAL

Inhibition of Encephalomyocarditis Virus and Poliovirus Replication by Quinacrine: Implications for the Design and Discovery of Novel Antiviral Drugs

(2010) A. V. Gasparian et al.   JOURNAL OF VIROLOGY

Autosomal dominant cerebellar ataxias: polyglutamine expansions and beyond

(2010) Alexandra Durr   LANCET NEUROLOGY

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

(2010) Chanseok Shin et al.   MOLECULAR CELL

Repeat expansion disease: progress and puzzles in disease pathogenesis

(2010) Albert R. La Spada et al.   NATURE REVIEWS GENETICS

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

The carboxy-terminal fragment of α1A calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells

(2009) Taro Ishiguro et al.   ACTA NEUROPATHOLOGICA

The Spinocerebellar Ataxias

(2009) Henry L Paulson   JOURNAL OF NEURO-OPHTHALMOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins

(2009) Bingbing Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CENTROIDFOLD: a web server for RNA secondary structure prediction

(2009) K. Sato et al.   NUCLEIC ACIDS RESEARCH

Direct functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sites

(2009) S. de Breyne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

(2009) S. L. Lian et al.   RNA

Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels

(2008) K. Watase et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA