Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation

Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo

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Regulatory T Cell Reprogramming toward a Th2-Cell-like Lineage Impairs Oral Tolerance and Promotes Food Allergy

(2015) Magali Noval Rivas et al.   IMMUNITY

CD4 + T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion

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Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms

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High IFN-γ and low SLPI mark severe asthma in mice and humans

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Innate immunological function of TH2 cells in vivo

(2015) Liying Guo et al.   NATURE IMMUNOLOGY

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

(2015) Christopher M. Evans et al.   Nature Communications

The cell biology of asthma

(2014) David J. Erle et al.   JOURNAL OF CELL BIOLOGY

Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure

(2014) Ashley G. Henderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Objective Measurement of Vitreous Inflammation Using Optical Coherence Tomography

(2014) Pearse A. Keane et al.   OPHTHALMOLOGY

Compartmentalized chemokine-dependent regulatory T-cell inhibition of allergic pulmonary inflammation

(2013) Roshi Afshar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mapping the Protein Domain Structures of the Respiratory Mucins: A Mucin Proteome Coverage Study

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T cell homing to epithelial barriers in allergic disease

(2012) Sabina A Islam et al.   NATURE MEDICINE

Innate and adaptive immune responses in asthma

(2012) Stephen T Holgate   NATURE MEDICINE

Comparison between major histocompatibility complex class II tetramer staining and surface expression of activation markers for the detection of allergen-specific CD4+ T cells

(2011) M. Bonvalet et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The sentinel role of the airway epithelium in asthma pathogenesis

(2011) Stephen T. Holgate   IMMUNOLOGICAL REVIEWS

Remodeling in asthma

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Asthma and Allergic Inflammation

(2010) Richard M. Locksley   CELL

Enriching quantitative proteomics with SIN

(2010) Mihaela E Sardiu et al.   NATURE BIOTECHNOLOGY

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging

(2009) Benjamin J Vakoc et al.   NATURE MEDICINE

Tracking epitope-specific T cells

(2009) James J Moon et al.   Nature Protocols

Mucus hypersecretion in asthma: causes and effects

(2008) Christopher M Evans et al.   CURRENT OPINION IN PULMONARY MEDICINE

Aeroallergen sensitization correlates with PC20 and exhaled nitric oxide in subjects with mild-to-moderate asthma

(2008) Timothy J. Craig et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY