Article
Public, Environmental & Occupational Health
Angus McLure, James J. Smith, Simon Matthew Firestone, Martyn D. Kirk, Nigel French, Emily Fearnley, Rhiannon Wallace, Mary Valcanis, Dieter Bulach, Cameron R. M. Moffatt, Linda A. Selvey, Amy Jennison, Danielle M. Cribb, Kathryn Glass
Summary: A study in Australia between 2017 and 2019 found that chickens were the main source of human Campylobacter infections, accounting for over 80%, with C. coli being more prevalent than C. jejuni. The study also revealed that the unsampled source accounted for 14% of cases, while ruminants and pigs accounted for 12% and 6% respectively. Therefore, interventions to reduce the burden of infection should focus on chickens.
Article
Environmental Sciences
Joscha Pueltz, Sabine Banzhaf, Markus Thuerkow, Richard Kranenburg, Martijn Schaap
Summary: The exposure to ambient particulate matter in metropolitan areas is a major health problem. We performed a source attribution of particulate matter in Berlin and found that households and industry & energy are the main sources. The PM2.5 in Berlin mainly originates from Germany itself, with contributions from transboundary transport.
ATMOSPHERIC ENVIRONMENT
(2023)
Article
Environmental Sciences
Bo Han, Lijie Wang, Zhiqiang Deng, Yilin Shi, Jian Yu
Summary: This study examines the contribution of Xinzheng International Airport in China to air pollution using a comprehensive approach. The findings highlight the importance of airport-related emissions as a major source impacting local air quality.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Microbiology
Lauren K. Hudson, William E. Andershock, Runan Yan, Mugdha Golwalkar, Nkuchia M. M'ikanatha, Irving Nachamkin, Linda S. Thomas, Christina Moore, Xiaorong Qian, Richard Steece, Katie N. Garman, John R. Dunn, Jasna Kovac, Thomas G. Denes
Summary: Campylobacteriosis is the most common bacterial foodborne illness in the United States and this study compared clinical and non-clinical Campylobacter populations from Tennessee and Pennsylvania, identified source attribution patterns through phylogenetic analyses, and identified potential outbreak clusters based on genomic similarity.
Article
Engineering, Electrical & Electronic
M. R. Marshall, D. Hellfeld, T. H. Y. Joshi, M. Salathe, M. S. Bandstra, K. J. Bilton, R. J. Cooper, J. C. Curtis, V. Negut, A. J. Shurley, K. Vetter
Summary: This study explores the use of LiDAR and streaming video for real-time object detection and tracking, and integrating this information with radiological data to enhance situational awareness and improve detection sensitivity. By implementing a custom system, the ability to correlate tracked object trajectories with spectroscopic gamma-ray data in real time and discriminate between source-carrying and nonsource-carrying objects is demonstrated. Additionally, the capability to track pedestrians and vehicles simultaneously in a simulated urban environment and utilize this information for improved detection sensitivity and situational awareness is showcased.
IEEE TRANSACTIONS ON NUCLEAR SCIENCE
(2021)
Article
Biotechnology & Applied Microbiology
Pierluigi Castelli, Andrea De Ruvo, Andrea Bucciacchio, Nicola D'Alterio, Cesare Camma, Adriano Di Pasquale, Nicolas Radomski
Summary: This study investigates the impact of different machine learning methods on the source prediction performance of L. monocytogenes genomic data. The results show that accessory genes and pan kmers had higher accuracy compared to core alleles and SNPs. The accuracy was higher with 80% training dataset splitting compared to other proportions. Near-zero variance removal did not significantly affect the accuracy of core alleles, accessory genes, and pan kmers, but significantly decreased the accuracy of core SNPs. SVM and XGB models performed better than other models in terms of accuracy.
Article
Microbiology
Lucas Harrison, Sampa Mukherjee, Chih-Hao Hsu, Shenia Young, Errol Strain, Qijing Zhang, Glenn E. Tillman, Cesar Morales, Jovita Haro, Shaohua Zhao
Summary: Utilizing core genome multilocus sequence typing and minimal multilocus distance methodology, the relative contribution of different sources of C. coli to human infections can be evaluated, serving as an indicator of antimicrobial resistance.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Physics, Applied
Mykola Isaiev, Yuliia Mankovska, Vasyl Kuryliuk, David Lacroix
Summary: This paper investigates thermal transport in nanoporous silicon with significant specific surface area. Equilibrium molecular dynamics approach and modified phonon transport kinetic theory-based approach were used to analyze thermal conductivity. Two models were employed to evaluate the phonon mean free path in the porous materials, with the second model considering the mean free path variation with porosity. The second model matches well with molecular dynamics simulations across all considered ranges of porosities, illustrating the importance of the phonon mean free path dependence with the porosity/volume fraction of composite materials.
APPLIED PHYSICS LETTERS
(2023)
Article
Water Resources
Yuanying Chen, Georgia Destouni, Romain Goldenberg, Carmen Prieto
Summary: The study quantified the main typological differences in nutrient load behavior versus water discharge for active and legacy sources in catchments draining into the Baltic Sea along the coastline of Sweden. Results showed dominant legacy source contributions to most monitored loads of TN and TP, with legacy concentrations being higher overall and changing more slowly than active or mixed sources. These convergent indications emphasize the need to identify and differentiate strategies targeting each source type for water quality improvement.
HYDROLOGICAL PROCESSES
(2021)
Article
Hospitality, Leisure, Sport & Tourism
Eunyoo Jang, Joanne Jung-Eun Yoo, Meehee Cho
Summary: This study explores how to improve restaurants' efforts to reduce particulate matter (PM) emissions by applying attribution theory. Results showed that attributing PM main sources to internal factors improves mitigation behavioral intentions, partially mediated by pollution prevention attitudes. Furthermore, cognitive risk judgments improve PM mitigation behavioral intentions when external source attributions are applied, while affective risk judgments enhance pollution prevention attitudes.
INTERNATIONAL JOURNAL OF CONTEMPORARY HOSPITALITY MANAGEMENT
(2023)
Article
Chemistry, Analytical
Uriel Tayvah, Jacob A. Spies, Jens Neu, Charles A. Schmuttenmaer
Summary: Terahertz spectroscopy is a powerful tool for extracting complex material properties, but extracting complex refractive indices from THz time-domain spectroscopy can be challenging. Modeling all possible paths through the sample as a tree structure can provide accurate results and better agreement than common approximations.
ANALYTICAL CHEMISTRY
(2021)
Article
Environmental Sciences
Rajesh Kumar, Cenlin He, Piyush Bhardwaj, Forrest Lacey, Rebecca R. Buchholz, Guy P. Brasseur, Warren Joubert, Casper Labuschagne, Elena Kozlova, Thumeka Mkololo
Summary: This study assesses the quality of CO simulations from WRF-Chem model in Africa and analyzes the processes controlling CO distribution. The model performs well in simulating temperature, precipitation, wind speed, and boundary layer height, but underestimates the Measurements of Pollution in the Troposphere (MOPITT) measurements and aircraft observed CO profiles. The study suggests outdated emissions, low biomass burning emissions, and biases in global CO models as potential contributors to the discrepancies between the model and MOPITT.
ATMOSPHERIC ENVIRONMENT
(2022)
Article
Multidisciplinary Sciences
Anthony J. Webster
Summary: This study combines the science of causal inference with established epidemiological methods to calculate the causal influence of risk factors on disease incidence. Using the results, the causal attribution of smoking and BMI to 226 diseases in the UK Biobank population is estimated. The findings provide new tools to quantify the causal influence of risk factors on disease.
SCIENTIFIC REPORTS
(2022)
Article
Geosciences, Multidisciplinary
Yongxin Ni, Xizhi Lv, Zhongbo Yu, Jianwei Wang, Li Ma, Qiufen Zhang
Summary: Accurately understanding the intra-annual variation in runoff evolution attribution is crucial for water resources management at the basin scale. This study quantitatively assessed the sensitivity and attribution differences of runoff changes in the Yellow River source area at different intra-annual time scales. The results reveal that the runoff in the Yellow River source area decreases during the flood season and spring, summer, and autumn, while increases during the non-flood season and winter. The underlying surface change is the dominant factor for annual runoff change, while climate change plays a significant role in the intraannual runoff change in different seasons.
Article
Psychology, Multidisciplinary
Yael Millgram, Matthew K. Nock, David D. Bailey, Amit Goldenberg
Summary: People's ability to regulate emotions is crucial to healthy emotional functioning. This study highlights the importance of knowledge about the source of emotions in emotion regulation. The findings suggest that higher knowledge about the source of negative emotions leads to more successful emotion regulation attempts, increased use of strategies targeting the source, and greater well-being.
PSYCHOLOGICAL SCIENCE
(2023)
Article
Environmental Sciences
Matthew S. Landis, William B. Studabaker, J. Patrick Pancras, Joseph R. Graney, Emily M. White, Eric S. Edgerton
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Chemistry, Multidisciplinary
Yamini Gopalapillai, Jane L. Kirk, Matthew S. Landis, Derek C. G. Muir, Colin A. Cooke, Amber Gleason, Allie Ho, Erin Kelly, David Schindler, Xiaowa Wang, Greg Lawson
ACS EARTH AND SPACE CHEMISTRY
(2019)
Article
Environmental Sciences
Matthew S. Landis, Shanti D. Berryman, Emily M. White, Joseph R. Graney, Eric S. Edgerton, William B. Studabaker
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Environmental Sciences
Eric S. Edgerton, Yu-Mei Hsu, Emily M. White, Mark E. Fenn, Matthew S. Landis
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Environmental Sciences
Matthew S. Landis, Russell W. Long, Jonathan Krug, Maribel Colon, Robert Vanderpool, Andrew Habel, Shawn P. Urbanski
Summary: Wildland fires can emit significant air pollution, prompting the need for quick and accurate measurement capabilities. The U.S. Environmental Protection Agency and other federal agencies sponsored the Wildland Fire Sensor Challenge to encourage innovation in detecting air pollution during wildfires. Results of the challenge showed improved accuracy of sensor systems, demonstrating their potential in providing reasonable accuracies during wildland fire events.
ATMOSPHERIC ENVIRONMENT
(2021)
Article
Environmental Sciences
Jonathan Krug, Russell Long, Maribel Colon, Andrew Habel, Shawn Urbanski, Matthew S. Landis
Summary: Wildland fire activity and particulate matter emissions have been increasing in the United States over the past two decades due to factors like increased temperature, drought, and high forest fuel loading. Monitoring networks are mainly concentrated in populous areas, leading to a lack of data in smaller towns affected by wildland fire smoke. Evaluation of small form factor PM2.5 samplers showed that only the ARA Instruments N-FRM Sampler met federal reference method guidelines for accuracy in both ambient and simulated wildland fire conditions.
ATMOSPHERIC ENVIRONMENT
(2021)
Article
Forestry
Joseph L. Wilkins, George Pouliot, Thomas Pierce, Amber Soja, Hyundeok Choi, Emily Gargulinski, Robert Gilliam, Jeffrey Vukovich, Matthew S. Landis
Summary: This study compares the performance of different algorithms in estimating smoke plume injection height (PIH) and suggests that meteorological inputs, temporal allocation, and heat release are the primary drivers for accurately modeling PIH.
INTERNATIONAL JOURNAL OF WILDLAND FIRE
(2022)
Article
Environmental Sciences
Andrew R. Whitehill, Russell W. Long, Shawn P. Urbanski, Maribel Colon, Andrew Habel, Matthew S. Landis
Summary: Cairpol and Aeroqual air quality sensors were tested on biomass burning plumes to measure CO, CO2, NO2, and other species. The sensors were evaluated based on their agreement with reference instruments in terms of accuracy, precision, and other metrics. The results indicated that CO and CO2 sensors performed well, while NO2 sensors performed less accurately. The study also found inconsistencies in the performance of other sensors and highlighted the interference of O-3 in Aeroqual NO2 sensors.
Article
Environmental Sciences
Karen D. Bradham, Clay M. Nelson, Tyler D. Sowers, Darren A. Lytle, Jennifer Tully, Michael R. Schock, Kevin Li, Matthew D. Blackmon, Kasey Kovalcik, David Cox, Gary Dewalt, Warren Friedman, Eugene A. Pinzer, Peter J. Ashley
Summary: This study conducted a national survey on the concentrations of lead, arsenic, and copper in drinking water in US homes. Using an exposure-based composite sampling approach, it found that some samples exceeded the safe thresholds for metal concentrations, and private well samples were more likely to exceed the thresholds.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2023)
Article
Engineering, Environmental
Russell W. Long, Shawn P. Urbanski, Emily Lincoln, Maribel Colon, Surender Kaushik, Jonathan D. Krug, Robert W. Vanderpool, Matthew S. Landis
Summary: Particulate matter (PM) from wildland fires poses health risks to individuals living in affected areas, and limiting exposure is crucial for protecting public health. However, monitoring PM concentrations in smoke impacted environments is challenging due to measurement interferences and sampling conditions. This study evaluates the accuracy of the Teledyne-API Model T640 PM Mass monitor compared to the filter-based federal reference method (FRM) for measuring PM2.5 in laboratory-based studies. The T640 has gained popularity for monitoring PM2.5 in the US, but the study finds both positive and negative measurement artifacts associated with PM concentration and smoke aerosol properties. Overall, this study highlights the importance of accurate PM monitoring during wildland fire events.
JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION
(2023)
Article
Environmental Sciences
Shawn P. Urbanski, Russell W. Long, Hannah Halliday, Emily N. Lincoln, Andrew Habel, Matthew S. Landis
Summary: Wildland fires have significant impacts on air quality and climate due to the emission of gases and aerosols. The use of prescribed fires as a forest management tool can potentially reduce the adverse impacts of smoke production and greenhouse gas emissions. Our study provides pollutant emission factors for different fuel components from forest ecosystems, which are important for evaluating the mitigation of adverse impacts on air quality and greenhouse gases.
ATMOSPHERIC ENVIRONMENT-X
(2022)
Article
Environmental Sciences
Mary M. Lynam, Lunia Oriol, Taylor Mann, J. Timothy Dvonch, James A. Barres, Lynne Gratz, Emily M. White, Matthew S. Landis, Natalie Mahowald, Chuanwu Xi, Allison L. Steiner
Summary: This study estimates the contributions of dry and wet deposition of total phosphorus (TP) to the Great Lakes region, using historical datasets and observing seasonal and geographic variations. The results indicate that wet deposition dominates over dry deposition in all lakes, except for Lake Huron. However, considering dry deposition of different particle sizes is necessary to accurately estimate the atmospheric deposition of TP over the Great Lakes.
ATMOSPHERIC ENVIRONMENT
(2023)
Article
Environmental Sciences
Amara L. Holder, Venkatesh Rao, Kasey Kovalcik, Larry Virtaranta
Summary: Wildland fires are a significant source of PM2.5 emissions in the US, including carbonaceous material and trace metals. Lead, a common pollutant, is emitted into the atmosphere through fires. This study measured lead concentrations in different types of biomass and calculated emission factors, providing data to improve our understanding of lead emissions.
ATMOSPHERIC ENVIRONMENT-X
(2023)
Article
Engineering, Environmental
Matthew S. Landis, Eric S. Edgerton
Summary: The Canadian Federal Government and the province of Alberta have implemented new and lower NO2 air quality standards. The Wood Buffalo Environmental Association conducted a three-year comparison of four NO2 analyzers in the Athabasca Oil Sands Region, and found that the data from all analyzers were highly correlated and in agreement.
JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION
(2023)
Article
Meteorology & Atmospheric Sciences
Russell W. Long, Andrew Whitehill, Andrew Habel, Shawn Urbanski, Hannah Halliday, Maribel Colon, Surender Kaushik, Matthew S. Landis
Summary: Wildland fires in the United States have significant impacts on air quality and human health, with primary concerns from fine particulate matter and ozone. Accurate measurement of O-3 concentrations near wildland fire plumes may be challenging due to interfering chemical species, but specific methodologies can help mitigate these interferences. The chemiluminescence FRM method is recommended for accurate O-3 measurements in wildland fire studies.
ATMOSPHERIC MEASUREMENT TECHNIQUES
(2021)
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)