Review
Chemistry, Inorganic & Nuclear
Yue Cao, Jia-Lin Zhou, Yanwen Ma, Yang Zhou, Jun-Jie Zhu
Summary: Metal nanoclusters (MeNCs) have attracted extensive interest in electrochemiluminescence (ECL) due to their unique properties and potential applications. This perspective provides a comprehensive overview of the recent advances in MeNCs in the ECL field, including their chemical and optical properties, synthesis strategies, and ECL sensing applications. The future prospects and challenges in this area are also discussed.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Analytical
Pinlong Zhao, Wenxin Zhu, Min Zheng, Jiandong Feng
Summary: A deep enhanced ECL microscopy (DEECL) method is proposed, which utilizes artificial neural networks to reconstruct electrochemiluminescence images with millisecond exposure times. DEECL achieves similar quality as high-quality electrochemiluminescence images with second-long exposure time. The DEECL method improves imaging efficiency by 1 to 2 orders than usual and achieves 85% accuracy in cell classification application.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Xiao Wei, Kenneth Chu, Jonathan Ralph Adsetts, Hao Li, Xi Kang, Zhifeng Ding, Manzhou Zhu
Summary: The interactions between SbF6- and metal nanoclusters have been studied in this work, revealing the effects of SbF6- ions on the reconstruction and rearrangement of nanoclusters. The optical properties of these nanoclusters have also been explored, with Pt1Ag30-SbF6 displaying high performance in phosphorescence quantum yield and ECL efficiency compared to Pt1Ag28-SbF6.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Review
Nanoscience & Nanotechnology
Hassan Nasrollahpour, Beatriz Jurado Sanchez, Mika Sillanpaa, Rasoul Moradi
Summary: Nanoclusters, consisting of few tens of atoms, have attracted significant attention in various fields due to their unique properties and applications. Compared to larger nanoparticles, nanoclusters exhibit distinct chemical, optical, and electrical properties. They can be used as signaling and/or reaction-accelerating materials in various sensing assays, showing enhanced properties. Nanoclusters also show great promise in terms of luminescence, with high quantum yield and better biocompatibility. They have opened new horizons in designing high-performance sensing and biosensing devices, offering excellent functionality and environmentally friendly properties.
ACS APPLIED NANO MATERIALS
(2023)
Review
Medicine, Research & Experimental
Shijun Wang, Shu Zhu, Ziqi Kang, Yidan Chen, Xiancheng Liu, Zixin Deng, Kun Hu, Guixue Wang, Yuchan Zhang, Guangchao Zang
Summary: The potential-resolved strategy has great value in ECL biosensing, especially in ratiometric ECL sensors, multiplex ECL sensors, and multicolor ECL sensors. It can provide more accurate analysis results and broader application prospects.
Review
Chemistry, Multidisciplinary
Siyang He, Maria Stratigaki, Silvia P. Centeno, Andreas Dreuw, Robert Goestl
Summary: The correlation between the mechanical properties of polymer materials and their molecular constituents has led to the development of optical force probes (OFPs) to study unique mechanical behaviors. Polymers exhibit diverse properties, requiring tailored OFP solutions to meet energy, time, and spatial resolution needs. Researchers continue to highlight notable examples and address future challenges in this emerging field.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Review
Chemistry, Analytical
Ruining Yang, Junbo Hu, Longsheng Zhang, Xingfen Liu, Yanqin Huang, Lei Zhang, Quli Fan
Summary: This review focuses on optical techniques and signal amplification strategies for the determination of telomerase activity. Various methods, such as fluorometric, colorimetry, chemiluminescence, surface-enhanced Raman scattering (SERS), and dual-mode techniques, are summarized for telomerase sensing and imaging. Two categories of signal amplification strategies, nucleic acid-based amplification and nanomaterial-assisted amplification, are discussed. Challenges and prospects are also addressed to provide insights for the development of multifunctional strategies and techniques for accurate cancer diagnosis.
Article
Chemistry, Analytical
Dongyang Wang, Xuwen Gao, Xiaoxuan Ren, Bin Zhang, Guizheng Zou
Summary: A single-stabilizer-capped strategy using L-cysteine as a capping agent is proposed to achieve highly efficient and surface-defect-involved electro-chemiluminescence from copper nanoclusters. The electrochemical injection of valence band holes into L-cysteine-capped copper nanoclusters results in eye-touchable electro-chemiluminescence processes. The capping agent of L-cysteine enables the copper nanoclusters to exhibit highly efficient and single-color emission in a surface-defect-involved route.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Junjun Ge, Jing Liang, Xufeng Chen, Yalei Deng, Pengwei Xiao, Jun-Jie Zhu, Yuanyuan Wang
Summary: Surface engineering is critical for enhancing the optical and electrochemical properties of nanomaterials. This study developed a general surface modification strategy to design all-inorganic MSCs and investigated their surface states using electrochemiluminescence.
Review
Chemistry, Multidisciplinary
Rengan Luo, Da Zhu, Huangxian Ju, Jianping Lei
Summary: Electrochemiluminescence (ECL) is a powerful technique that relies on charge transfer between electrochemical intermediates and co-reactants/emitters to form excited emitters. The development of molecular nanocrystals, such as metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), has allowed for the exploration of ECL mechanisms and enhancement strategies. Reticular crystalline nanoemitters with different topologies provide a platform for understanding ECL fundamentals and designing next-generation ECL devices.
ACCOUNTS OF CHEMICAL RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Xiangui Ma, Wenyue Gao, Fangxin Du, Fan Yuan, Jing Yu, Yiran Guan, Neso Sojic, Guobao Xu
Summary: Electrochemiluminescence (ECL) combines electrochemical and chemiluminescent methods, used in clinical analysis and biological research. Efforts focus on enhancing sensitivity, portability, and affordability of ECL devices. The research aims to develop new electrodes, wireless power transfer (WPT) based devices, and novel bipolar electrochemistry.
ACCOUNTS OF CHEMICAL RESEARCH
(2021)
Article
Chemistry, Analytical
Shu-Shu Song, Jiale Zhan, Hao-Tian Zhu, Jing-Yi Bao, Ai-Jun Wang, Pei-Xin Yuan, Jiu-Ju Feng
Summary: This study investigates the use of palladium nanospheres-embedded metal-organic frameworks to enhance the electrochemiluminescence efficiency of organic emitters in aqueous solutions, leading to the development of a highly efficient electrochemiluminescence sensor.
Article
Chemistry, Multidisciplinary
Emily Kerr, Richard Alexander, Paul S. Francis, Rosanne M. Guijt, Gregory J. Barbante, Egan H. Doeven
Summary: The study found that unmodified carbon-based SPEs exhibited the most intense ECL signals in detection systems, and the incorporation of nanomaterials did not significantly enhance ECL intensity. Platinum and gold SPEs showed lower relative ECL intensities compared to carbonaceous materials, but the ECL signal at platinum electrodes could be increased by approximately 3-fold with the addition of a surfactant.
FRONTIERS IN CHEMISTRY
(2021)
Article
Engineering, Environmental
Zhongnan Huang, Zhenglian Li, Zhimin Weng, Paramasivam Balasubramanian, Mingchun Lai, Wei Chen, Juewen Liu, Huaping Peng
Summary: In this study, a model system was developed to evaluate the effect of electrocatalysis (EC) on electrochemiluminescence (ECL) through kinetic analysis of electrocatalytic reactions. The results demonstrated a dual EC-mediated ECL enhancement and identified the catalytically active sites. With a better understanding of the EC mechanism, the researchers successfully used EC to regulate ECL and developed a biosensor with a record low limit of detection.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Chemistry, Analytical
Junjun Ge, Xufeng Chen, Jinling Yang, Yuanyuan Wang
Summary: Luminescent nanoclusters (NCs) are emerging as novel electrochemiluminescence (ECL) emitters due to their easy preparation, ultrafine size, low toxicity, and excellent photostability. This mini-review discusses the recent development of NCs in ECL, focusing on their optical properties, classification, factors affecting quantum yield (QY), and ECL mechanisms based on NCs, as well as potential applications in tumor markers test, immunoassay, and serum test. This review aims to provide a comprehensive summary of NCs' progress in ECL and encourage researchers to explore their future applications in ECL.
