An unprecedented mechanism of nucleotide methylation in organisms containing thyX

Synthesis and application of isotopically labeled flavin nucleotides

(2015) Tatiana V. Mishanina et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Detection of Intermediates in the Oxidative Half-Reaction of the FAD-Dependent Thymidylate Synthase from Thermotoga maritima: Carbon Transfer without Covalent Pyrimidine Activation

(2014) John A. Conrad et al.   BIOCHEMISTRY

Substrate Activation in Flavin-Dependent Thymidylate Synthase

(2014) Tatiana V. Mishanina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of an Acyclic Nucleoside Phosphonate that InhibitsMycobacterium tuberculosisThyX Based on the Binding Mode of a 5-Alkynyl Substrate Analogue

(2013) Anastasia Parchina et al.   ChemMedChem

Synthesis and Evaluation of 6-Aza-2′-deoxyuridine Monophosphate Analogs as Inhibitors of Thymidylate Synthases, and as Substrates or Inhibitors of Thymidine Monophosphate Kinase in Mycobacterium tuberculosis

(2012) Martin Kögler et al.   CHEMISTRY & BIODIVERSITY

Trapping of an Intermediate in the Reaction Catalyzed by Flavin-Dependent Thymidylate Synthase

(2012) Tatiana V. Mishanina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FAD/Folate-Dependent tRNA Methyltransferase: Flavin as a New Methyl-Transfer Agent

(2012) Djemel Hamdane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Folate binding site of flavin-dependent thymidylate synthase

(2012) E. M. Koehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and Evaluation of 5-Substituted 2′-deoxyuridine Monophosphate Analogues As Inhibitors of Flavin-Dependent Thymidylate Synthase inMycobacterium tuberculosis

(2011) Martin Kögler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mycobacterium tuberculosis thymidylate synthase gene thyX is essential and potentially bifunctional, while thyA deletion confers resistance to p-aminosalicylic acid

(2011) A. S. Fivian-Hughes et al.   MICROBIOLOGY-SGM

An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene

(2009) Eric M. Koehn et al.   NATURE