Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

(2015) Philippe Goyette et al.   NATURE GENETICS

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

(2015)   NATURE NEUROSCIENCE

Are Anti-inflammatory Therapies Viable Treatments for Psychiatric Disorders?

(2015) Andrew H. Miller et al.   JAMA Psychiatry

Elevated Maternal C-Reactive Protein and Increased Risk of Schizophrenia in a National Birth Cohort

(2014) Sarah Canetta et al.   AMERICAN JOURNAL OF PSYCHIATRY

A Genotype-First Approach to Defining the Subtypes of a Complex Disease

(2014) Holly A. Stessman et al.   CELL

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Meta-analysis of the association between N-methyl-d-aspartate receptor antibodies and schizophrenia, schizoaffective disorder, bipolar disorder, and major depressive disorder

(2014) Daniel M. Pearlman et al.   SCHIZOPHRENIA RESEARCH

Recurrent de novo mutations implicate novel genes underlying simplex autism risk

(2014) B. J. O'Roak et al.   Nature Communications

A Nationwide Study on the Risk of Autoimmune Diseases in Individuals With a Personal or a Family History of Schizophrenia and Related Psychosis

(2013) Michael E. Benros et al.   AMERICAN JOURNAL OF PSYCHIATRY

Immune System Disturbances in Schizophrenia

(2013) Szatmár Horváth et al.   BIOLOGICAL PSYCHIATRY

Transient Maternal IL-6 Mediates Long-Lasting Changes in Neural Stem Cell Pools by Deregulating an Endogenous Self-Renewal Pathway

(2013) Denis Gallagher et al.   Cell Stem Cell

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement

(2013) Allison R Bialas et al.   NATURE NEUROSCIENCE

Efficacy of Anti-inflammatory Agents to Improve Symptoms in Patients With Schizophrenia: An Update

(2013) I. E. Sommer et al.   SCHIZOPHRENIA BULLETIN

The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

(2012) Wouter Beumer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia

(2012) S G Fillman et al.   MOLECULAR PSYCHIATRY

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: Associations and functional implications

(2012) Monojit Debnath et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Childhood infection and adult schizophrenia: A meta-analysis of population-based studies

(2012) Golam M. Khandaker et al.   SCHIZOPHRENIA RESEARCH

Meta-Analysis of Cytokine Alterations in Schizophrenia: Clinical Status and Antipsychotic Effects

(2011) Brian J. Miller et al.   BIOLOGICAL PSYCHIATRY

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Maternal Influenza Infection During Pregnancy Impacts Postnatal Brain Development in the Rhesus Monkey

(2010) Sarah J. Short et al.   BIOLOGICAL PSYCHIATRY

NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy

(2010) Raquel Gómez-Sintes et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

(2010) Amy Strange et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Common variants conferring risk of schizophrenia: A pathway analysis of GWAS data

(2010) Peilin Jia et al.   SCHIZOPHRENIA RESEARCH

Accurately Assessing the Risk of Schizophrenia Conferred by Rare Copy-Number Variation Affecting Genes with Brain Function

(2010) Soumya Raychaudhuri et al.   PLoS Genetics

Common variants conferring risk of schizophrenia

(2009) Hreinn Stefansson et al.   NATURE

Mutations inSYNGAP1in Autosomal Nonsyndromic Mental Retardation

(2009) Fadi F. Hamdan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial Hsp60 Chaperonopathy Causes an Autosomal-Recessive Neurodegenerative Disorder Linked to Brain Hypomyelination and Leukodystrophy

(2008) Daniella Magen et al.   AMERICAN JOURNAL OF HUMAN GENETICS