Deazaguanine derivatives, examples of crosstalk between RNA and DNA modification pathways

Biosynthesis and Function of Modified Bases in Bacteria and Their Viruses

(2016) Peter Weigele et al.   CHEMICAL REVIEWS

The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA

(2016) Dan Dominissini et al.   NATURE

Novel genomic island modifies DNA with 7-deazaguanine derivatives

(2016) Jennifer J. Thiaville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation

(2016) Albert Jeltsch et al.   RNA Biology

Messenger RNA modifications: Form, distribution, and function

(2016) W. V. Gilbert et al.   SCIENCE

The APOBEC Protein Family: United by Structure, Divergent in Function

(2016) Jason D. Salter et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Single Enzyme Transforms a Carboxylic Acid into a Nitrile through an Amide Intermediate

(2015) Micah T. Nelp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PreQ0 Base, an Unusual Metabolite with Anti-cancer Activity from Streptomyces qinglanensis 172205

(2015) Dongbo Xu et al.   Anti-Cancer Agents in Medicinal Chemistry

Radical-mediated ring contraction in the biosynthesis of 7-deazapurines

(2015) Vahe Bandarian et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

(2015) Bogdan I. Fedeles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multisite-specific archaeosine tRNA-guanine transglycosylase (ArcTGT) fromThermoplasma acidophilum, a thermo-acidophilic archaeon

(2015) Takuya Kawamura et al.   NUCLEIC ACIDS RESEARCH

Effects of tRNA modification on translational accuracy depend on intrinsic codon–anticodon strength

(2015) Nandini Manickam et al.   NUCLEIC ACIDS RESEARCH

Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine

(2015) Martin Müller et al.   NUCLEIC ACIDS RESEARCH

The Queuine Micronutrient: Charting a Course from Microbe to Man

(2015) Claire Fergus et al.   Nutrients

Regulation of DNA phosphorothioate modification in Salmonella enterica by DndB

(2015) Wei He et al.   Scientific Reports

Wybutosine biosynthesis: Structural and mechanistic overview

(2015) Phanélie Perche-Letuvée et al.   RNA Biology

Plant, Animal, and Fungal Micronutrient Queuosine Is Salvaged by Members of the DUF2419 Protein Family

(2014) Rémi Zallot et al.   ACS Chemical Biology

Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily

(2014) Zachary D. Miles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptome-Wide Mapping of Pseudouridines: Pseudouridine Synthases Modify Specific mRNAs in S. cerevisiae

(2014) Alexander F. Lovejoy et al.   PLoS One

Genomic Sequencing and Biological Characteristics of a Novel Escherichia Coli Bacteriophage 9g, a Putative Representative of a New Siphoviridae Genus

(2014) Eugene Kulikov et al.   Viruses-Basel

A Nutrient-Driven tRNA Modification Alters Translational Fidelity and Genome-wide Protein Coding across an Animal Genus

(2014) John M. Zaborske et al.   PLOS BIOLOGY

Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism

(2013) Daniel P Dowling et al.   Nature Chemical Biology

The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST)

(2013) Ross Overbeek et al.   NUCLEIC ACIDS RESEARCH

Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA

(2013) Lakshminarayan M. Iyer et al.   NUCLEIC ACIDS RESEARCH

Queuosine Biosynthesis Is Required for Sinorhizobium meliloti-Induced Cytoskeletal Modifications on HeLa Cells and Symbiosis with Medicago truncatula

(2013) Marta Marchetti et al.   PLoS One

Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor

(2013) Inna Biela et al.   PLoS One

Studies of translational misreading in vivo show that the ribosome very efficiently discriminates against most potential errors

(2013) N. Manickam et al.   RNA

Biosynthesis of pyrrolopyrimidines

(2012) Reid M. McCarty et al.   BIOORGANIC CHEMISTRY

Structural Basis of Biological Nitrile Reduction

(2012) Vimbai M. Chikwana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Characterization of Novel Salmonella Mobile Elements Involved in the Dissemination of Genes Linked to Virulence and Transmission

(2012) Andrea I. Moreno Switt et al.   PLoS One

Diversity of Archaeosine Synthesis in Crenarchaeota

(2011) Gabriela Phillips et al.   ACS Chemical Biology

Functional Promiscuity of the COG0720 Family

(2011) Gabriela Phillips et al.   ACS Chemical Biology

Queuosine Deficiency in Eukaryotes Compromises Tyrosine Production through Increased Tetrahydrobiopterin Oxidation

(2011) Tatsiana Rakovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Discovery of epoxyqueuosine (oQ) reductase reveals parallels between halorespiration and tRNA modification

(2011) Z. D. Miles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA

(2011) Erwin van den Born et al.   Nature Communications

Structure and Function of Mammalian DNA Methyltransferases

(2010) Renata Zofia Jurkowska et al.   CHEMBIOCHEM

Genome Annotation and Intraviral Interactome for the Streptococcus pneumoniae Virulent Phage Dp-1

(2010) M. Sabri et al.   JOURNAL OF BACTERIOLOGY

Discovery and Characterization of an Amidinotransferase Involved in the Modification of Archaeal tRNA

(2010) Gabriela Phillips et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-Resolution Structure of the Nitrile Reductase QueF Combined with Molecular Simulations Provide Insight into Enzyme Mechanism

(2010) Youngchang Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Specificity shifts in the rRNA and tRNA nucleotide targets of archaeal and bacterial m5U methyltransferases

(2010) S. Auxilien et al.   RNA

Towards a Systems Approach in the Genetic Analysis of Archaea: Accelerating Mutant Construction and Phenotypic Analysis inHaloferax volcanii

(2010) Ian K. Blaby et al.   ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL

Escherichia coliQueD Is a 6-Carboxy-5,6,7,8-tetrahydropterin Synthase†

(2009) Reid M. McCarty et al.   BIOCHEMISTRY

The Deazapurine Biosynthetic Pathway Revealed: In Vitro Enzymatic Synthesis of PreQ0from Guanosine 5′-Triphosphate in Four Steps

(2009) Reid M. McCarty et al.   BIOCHEMISTRY

Queuosine modification of tRNA: its divergent role in cellular machinery

(2009) Manjula Vinayak et al.   BIOSCIENCE REPORTS

Zinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IB

(2009) B. Sankaran et al.   JOURNAL OF BACTERIOLOGY

Queuosine Formation in Eukaryotic tRNA Occurs via a Mitochondria-localized Heteromeric Transglycosylase

(2009) Coilin Boland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Integrative Approach Combining Noncovalent Mass Spectrometry, Enzyme Kinetics and X-ray Crystallography to Decipher Tgt Protein-Protein and Protein-RNA Interaction

(2009) Tina Ritschel et al.   JOURNAL OF MOLECULAR BIOLOGY

Deciphering Deazapurine Biosynthesis: Pathway for Pyrrolopyrimidine Nucleosides Toyocamycin and Sangivamycin

(2008) Reid M. McCarty et al.   CHEMISTRY & BIOLOGY

Biosynthesis of 7-Deazaguanosine-Modified tRNA Nucleosides: a New Role for GTP Cyclohydrolase I

(2008) G. Phillips et al.   JOURNAL OF BACTERIOLOGY

A Novel Class of Modular Transporters for Vitamins in Prokaryotes

(2008) D. A. Rodionov et al.   JOURNAL OF BACTERIOLOGY

Crystal structure of QueC from Bacillus subtilis: An enzyme involved in preQ1 biosynthesis

(2008) Nenad Cicmil et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS