Article
Endocrinology & Metabolism
Chen Yang, Shuheng Yang, Wei Zheng, Ruowen Zu, Shiyu Ran, Huan Wu, Bingnan Ren, Ning Lv, Yihui Kuang, Mengna Li, Jiangbo Du, Yichun Guan
Summary: This study found that a 60-day weight reduction intervention prior to IVF/ICSI may increase neonatal birth weight, reduce maternal blood glucose concentration, and improve maternal insulin resistance in infertile overweight or obese women. As the weight loss ratio increased, the incidence of hypertensive disorders of pregnancy, premature membrane rupture, premature delivery, stillbirth, and low birth weight showed a downward trend.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Hadas Ganer Herman, Yossi Mizrachi, Ayala Shevach Alon, Yasmin Farhadian, Ohad Gluck, Jacob Bar, Michal Kovo, Arieh Raziel
Summary: In vitro fertilization (IVF) pregnancies following fresh and frozen embryo transfer have the same obstetric and perinatal outcomes when compared in the same women.
REPRODUCTIVE SCIENCES
(2022)
Article
Endocrinology & Metabolism
Yi-Chen He, Kai-Zhen Su, Jie Cai, Qing-Xia Meng, Yan-Ting Wu, He-Feng Huang
Summary: This study explored the association between anti-Mullerian hormone (AMH) levels and perinatal outcomes in women undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). The study found that abnormal AMH levels increased the risk of intrahepatic cholestasis of pregnancy (ICP) regardless of the number of live births, while high AMH levels increased the risks of gestational diabetes mellitus (GDM) and pregnancy-induced hypertension (PIH) in multiple deliveries. However, there was no association between AMH levels and adverse neonatal outcomes.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
Meijuan Peng, Mingyang Wen, Tao Jiang, Yangqian Jiang, Hong Lv, Ting Chen, Xiufeng Ling, Hong Li, Qingxia Meng, Boxian Huang, Shiyao Tao, Lei Huang, Cong Liu, Xin Xu, Qun Lu, Xiaoyu Liu, Bo Xu, Xiumei Han, Kun Zhou, Jiaping Chen, Yuan Lin, Hongxia Ma, Yankai Xia, Hongbing Shen, Zhibin Hu, Feng Chen, Jiangbo Du, Guangfu Jin
Summary: This study aimed to investigate the association of pre-treatment psychological distress with clinical pregnancy rate among infertility couples undergoing IVF/ICSI treatment. The findings indicated that psychological distress experienced prior to treatment was not associated with clinical pregnancy outcomes.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Dongxin Lin, Pengsheng Li, Dazhi Fan, Gengdong Chen, Shuzhen Wu, Shaoxin Ye, Huiting Ma, Jiaming Rao, Zixing Zhou, Meng Zeng, Zheng Huang, Xiaoling Guo, Zhengping Liu
Summary: This study evaluated preterm birth and perinatal outcomes in IVF/ICSI dichorionic-diamnionic twin pregnancies compared to spontaneous twin pregnancies. IVF/ICSI twin pregnancies showed a slight increase in preterm birth, iatrogenic preterm birth, and NICU admission but a decrease in PPROM. Other outcomes were similar between IVF/ICSI and spontaneous twin pregnancies.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Review
Medicine, General & Internal
Lauren Lacey, Sibte Hassan, Sebastian Franik, Mourad W. Seif, M. Ahsan Akhtar
Summary: The effects of assisted hatching (AH) on live birth rates are uncertain and may increase the risk of multiple pregnancies. Although AH may offer a slightly increased chance of achieving a clinical pregnancy, the quality of data is low, and it is uncertain whether it influences miscarriage rates.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Review
Cell Biology
Domenico Baldini, Daniele Ferri, Giorgio Maria Baldini, Dario Lot, Assunta Catino, Damiano Vizziello, Giovanni Vizziello
Summary: In assisted reproductive technology (ART), the selection of sperm cells is crucial for fertilization potential, with intracytoplasmic sperm injection (ICSI) being the most widely used technique. Various methods have been developed to mimic natural selection processes, but doubts and disagreements on the most effective technique remain.
Article
Obstetrics & Gynecology
Di Chen, Xiaoyan Mao, Jie Zhang, Ling Wu
Summary: This study suggests that the maternal ABO blood type may influence the obstetric and perinatal outcomes following frozen embryo transfer (FET). The study found that different ABO blood types were associated with different risks of gestational diabetes mellitus, large for gestational age babies, hypertensive diseases of pregnancy, and low birthweight in both singleton and twin pregnancies. These findings highlight the importance of patient characteristics in affecting the outcomes of IVF.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Endocrinology & Metabolism
Yilei He, Rong Li, Jingwen Yin, Zi Yang, Yuanyuan Wang, Lixue Chen, Shuo Yang, Jie Qiao
Summary: This retrospective study analyzed the levels of inflammatory factors in PCOS patients with different BMI groups and their impact on IVF/ICSI pregnancy outcomes. The results showed that PCOS patients in the high BMI group had lower oocyte and good quality embryo numbers, as well as higher levels of IL-6 and lower cumulative clinical pregnancy and live birth rates. High TNF-alpha was negatively correlated with pregnancy rates, while high IL-1 beta was positively correlated with live birth rates among PCOS patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Obstetrics & Gynecology
Wenhui Hou, Gaohui Shi, Yuanlin Ma, Yongxiang Liu, Manman Lu, Xiuli Fan, Yingpu Sun
Summary: The study found that preimplantation genetic testing (PGT) does not increase the risk of adverse obstetric outcomes, but is associated with a higher risk of hypertensive disorders of pregnancy and further investigation is needed for the risk of IUGR.
FERTILITY AND STERILITY
(2021)
Article
Endocrinology & Metabolism
Zhiqi Liao, Lei Cai, Chang Liu, Jie Li, Xinyao Hu, Youhua Lai, Lin Shen, Cong Sui, Hanwang Zhang, Kun Qian
Summary: A predictive nomogram model was constructed based on 11513 IVF/ICSI singleton live births, identifying 14 risk factors associated with preterm delivery. The model exhibited good performance and calibration, suggesting its potential clinical value.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Reproductive Biology
Luisa Ramirez-Agamez, Camilo Hernandez-Aviles, Dickson D. Varner, Charles C. Love
Summary: This study explores stallion-associated factors in intracytoplasmic sperm injection (ICSI) using frozen/thawed sperm. The results indicate that the composition of freezing extender affects the developmental competence of sperm and in vitro-matured equine oocytes after ICSI. Furthermore, there were no significant differences observed when using ejaculated or epididymal sperm, or sperm with different morphological features in ICSI outcomes.
Article
Obstetrics & Gynecology
Adva Aizer, Alon Lazarovich, Olga Dratviman-Storobinsky, Meirav Noach-Hirsh, Jigal Haas, Avi Jacob, Gil Raviv, Raoul Orvieto
Summary: The study found that in ICSI cycles, using motile spermatozoa obtained from TESA or TESE resulted in higher pregnancy and live birth rates compared to using immotile spermatozoa. While fertilization rates and embryo quality decreased with the use of immotile spermatozoa, ICSI remained a valid option for couples.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Endocrinology & Metabolism
Shiyu Ran, Ruowen Zu, Huan Wu, Wei Zheng, Chen Yang, Shuheng Yang, Bingnan Ren, Wen Zhang, Jiangbo Du, Yichun Guan
Summary: This study evaluated the perinatal outcomes of women with late moderate-to-severe ovarian hyperstimulation syndrome (OHSS) who underwent in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). The study found that the perinatal outcomes were similar between the two groups. However, further investigations with larger sample sizes are needed due to the limited number of patients with late MS-OHSS in this study.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Christopher P. Allen, David J. McLernon, Sohinee Bhattahcharya, Abha Maheshwari
Summary: This study analyzed the association between donor sperm and perinatal outcomes of live births conceived via IVF. The results showed that singleton live births conceived with donor sperm had a lower risk of very preterm and preterm birth, while the risk of low and high birthweight was also affected. For liveborn twins conceived with donor sperm, there was a lower risk of very low and low birthweight, and a suggestion of a reduced risk of very preterm and preterm birth. The study concludes that there is no greater chance of adverse outcomes for IVF live births conceived with donor sperm compared to partner sperm.
FERTILITY AND STERILITY
(2022)