Pharmacokinetic-pharmacodynamic analyses of antihypertensive drugs, nifedipine and propranolol, in spontaneously hypertensive rats to investigate characteristics of effect and side effects

标题
Pharmacokinetic-pharmacodynamic analyses of antihypertensive drugs, nifedipine and propranolol, in spontaneously hypertensive rats to investigate characteristics of effect and side effects
作者
关键词
Antihypertensive drug, Nifedipine, Propranolol, Pharmacokinetic-pharmacodynamic (PK-PD) modeling, Spontaneously hypertensive rat (SHR), Blood pressure, Heart rate, QT interval
出版物
REGULATORY TOXICOLOGY AND PHARMACOLOGY
Volume 76, Issue -, Pages 21-29
出版商
Elsevier BV
发表日期
2016-01-08
DOI
10.1016/j.yrtph.2016.01.003

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