期刊
CHINESE JOURNAL OF ORGANIC CHEMISTRY
卷 35, 期 1, 页码 29-38出版社
SCIENCE PRESS
DOI: 10.6023/cjoc201406003
关键词
Mitsunobu reaction; chemical bond; reaction mechanism; stereoselectivity; regioselectivity
资金
- Qing Lan Talent Engineering Funds of Lanzhou Jiaotong University [QL-06-01A]
The Mitsunobu reaction is an effective method for making a new chemical bond by condensation of an alcohol with an acidic compound. It can be applied for the construction of C-O, C-N, C-S and C-C bonds, and has been widely used in the synthesis of natural products and functional organic molecules. In this review, the mechanism of the Mitsunobu reaction and its application in the construction of chemical bonds are introduced. Moreover, the regioselectivity of this reaction is systematically summarized.
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