Temperate phages both mediate and drive adaptive evolution in pathogen biofilms

Temperate phages enhance pathogen fitness in chronic lung infection

(2016) Emily V Davies et al.   ISME Journal

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Divergent, CoexistingPseudomonas aeruginosaLineages in Chronic Cystic Fibrosis Lung Infections

(2015) David Williams et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs

(2015) Peter Jorth et al.   Cell Host & Microbe

Polylysogeny magnifies competitiveness of a bacterial pathogenin vivo

(2015) Nicola Burns et al.   Evolutionary Applications

Genes Required for Free Phage Production are Essential forPseudomonas aeruginosaChronic Lung Infections

(2015) Andrée-Ann Lemieux et al.   JOURNAL OF INFECTIOUS DISEASES

Experimental evolution can unravel the complex causes of natural selection in clinical infections

(2015) Michael A. Brockhurst   MICROBIOLOGY-SGM

Fitness cost of antibiotic susceptibility during bacterial infection

(2015) Damien Roux et al.   Science Translational Medicine

Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung

(2015) Julio Diaz Caballero et al.   mBio

Independent Co-Option of a Tailed Bacteriophage into a Killing Complex in Pseudomonas

(2015) Kevin L. Hockett et al.   mBio

Lytic activity by temperate phages of Pseudomonas aeruginosa in long-term cystic fibrosis chronic lung infections

(2014) Chloe E James et al.   ISME Journal

Pseudomonas aeruginosaMinor Pilins Prime Type IVa Pilus Assembly and Promote Surface Display of the PilY1 Adhesin

(2014) Ylan Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Loss of Social Behaviours in Populations of Pseudomonas aeruginosa Infecting Lungs of Patients with Cystic Fibrosis

(2014) Natalie Jiricny et al.   PLoS One

Pervasive domestication of defective prophages by bacteria

(2014) L.-M. Bobay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acyl-Homoserine Lactone Quorum Sensing: From Evolution to Application

(2013) Martin Schuster et al.   Annual Review of Microbiology

LTQ-XL mass spectrometry proteome analysis expands the Pseudomonas aeruginosa AmpR regulon to include cyclic di-GMP phosphodiesterases and phosphoproteins, and identifies novel open reading frames

(2013) Hansi Kumari et al.   Journal of Proteomics

Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome

(2013) Sheetal R. Modi et al.   NATURE

The Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue

(2013) J. Knepper et al.   mBio

Differential infection properties of three inducible prophages from an epidemic strain of Pseudomonas aeruginosa

(2012) Chloe E James et al.   BMC MICROBIOLOGY

Contribution of phage-derived genomic islands to the virulence of facultative bacterial pathogens

(2012) Ben Busby et al.   ENVIRONMENTAL MICROBIOLOGY

Transmissible strains ofPseudomonas aeruginosain cystic fibrosis lung infections

(2012) Joanne L. Fothergill et al.   EUROPEAN RESPIRATORY JOURNAL

The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa

(2012) P. Nadal Jimenez et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Adaptation of Temperate Bacteriophages to Their Host Genomes

(2012) Louis-Marie Bobay et al.   MOLECULAR BIOLOGY AND EVOLUTION

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

(2012) Anders Folkesson et al.   NATURE REVIEWS MICROBIOLOGY

Self-produced exopolysaccharide is a signal that stimulates biofilm formation in Pseudomonas aeruginosa

(2012) Y. Irie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomics of Adaptation during Experimental Evolution of the Opportunistic Pathogen Pseudomonas aeruginosa

(2012) Alex Wong et al.   PLoS Genetics

The Transcription Factor AmrZ Utilizes Multiple DNA Binding Modes to Recognize Activator and Repressor Sequences of Pseudomonas aeruginosa Virulence Genes

(2012) Edward E. Pryor et al.   PLoS Pathogens

Use of Artificial Sputum Medium to Test Antibiotic Efficacy Against Pseudomonas aeruginosa in Conditions More Relevant to the Cystic Fibrosis Lung

(2012) Sebastian Kirchner et al.   Jove-Journal of Visualized Experiments

Pseudomonas aeruginosaPopulation Diversity and Turnover in Cystic Fibrosis Chronic Infections

(2011) Eilidh Mowat et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

Type VI Secretion System inPseudomonas aeruginosa

(2011) Abderrahman Hachani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes

(2011) Tami D Lieberman et al.   NATURE GENETICS

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Pseudomonas aeruginosa: all roads lead to resistance

(2011) Elena B.M. Breidenstein et al.   TRENDS IN MICROBIOLOGY

Competition and Dispersal in Pseudomonas aeruginosa

(2010) Tiffany B. Taylor et al.   AMERICAN NATURALIST

Effect of Antibiotic Treatment on Bacteriophage Production by a Cystic Fibrosis Epidemic Strain ofPseudomonasaeruginosa

(2010) Joanne L. Fothergill et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Pseudomonas aeruginosa Minor Pilins Are Incorporated into Type IV Pili

(2010) Carmen L. Giltner et al.   JOURNAL OF MOLECULAR BIOLOGY

Pseudomonas aeruginosa biofilm matrix polysaccharide Psl is regulated transcriptionally by RpoS and post-transcriptionally by RsmA

(2010) Yasuhiko Irie et al.   MOLECULAR MICROBIOLOGY

Quorum Sensing and Virulence of Pseudomonas aeruginosa during Lung Infection of Cystic Fibrosis Patients

(2010) Thomas Bjarnsholt et al.   PLoS One

Acyl-Homoserine Lactones Can Induce Virus Production in Lysogenic Bacteria: an Alternative Paradigm for Prophage Induction

(2009) D. Ghosh et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biopython: freely available Python tools for computational molecular biology and bioinformatics

(2009) P. J. A. Cock et al.   BIOINFORMATICS

The bacteriophages in human- and animal body-associated microbial communities

(2009) A. Letarov et al.   JOURNAL OF APPLIED MICROBIOLOGY

Single-Residue Changes in the C-Terminal Disulfide-Bonded Loop of the Pseudomonas aeruginosa Type IV Pilin Influence Pilus Assembly and Twitching Motility

(2009) H. Harvey et al.   JOURNAL OF BACTERIOLOGY

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

The role of quorum sensing in chronic cystic fibrosisPseudomonas aeruginosainfections

(2008) Craig Winstanley et al.   FEMS MICROBIOLOGY LETTERS

Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa

(2008) C. Winstanley et al.   GENOME RESEARCH

Identification of FleQ fromPseudomonas aeruginosaas a c-di-GMP-responsive transcription factor

(2008) Jason W. Hickman et al.   MOLECULAR MICROBIOLOGY