Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis

Huntingtin is required for ciliogenesis and neurogenesis during early Xenopus development

(2015) Tomomi Haremaki et al.   DEVELOPMENTAL BIOLOGY

Huntingtin-lowering strategies in Huntington's disease: Antisense oligonucleotides, small RNAs, and gene editing

(2014) Neil Aronin et al.   MOVEMENT DISORDERS

Huntington disease: natural history, biomarkers and prospects for therapeutics

(2014) Christopher A. Ross et al.   Nature Reviews Neurology

Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A

(2014) K. P. Bhat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into the pathogenesis of pancreatitis

(2013) Raghuwansh P. Sah et al.   CURRENT OPINION IN GASTROENTEROLOGY

MRI measures of corpus callosum iron and myelin in early Huntington's disease

(2013) M. Di Paola et al.   HUMAN BRAIN MAPPING

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy

(2013) Jong-Min Lee et al.   HUMAN MOLECULAR GENETICS

Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms

(2013) Qiaoqiao Xu et al.   JOURNAL OF CELL BIOLOGY

Isolation and Culture of Mouse Primary Pancreatic Acinar Cells

(2013) Johann Gout et al.   Jove-Journal of Visualized Experiments

Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain

(2012) Dyna I. Shirasaki et al.   NEURON

Using non-coding small RNAs to develop therapies for Huntington's disease

(2011) Y Zhang et al.   GENE THERAPY

Spatial and Temporal Requirements for huntingtin (Htt) in Neuronal Migration and Survival during Brain Development

(2011) Y. Tong et al.   JOURNAL OF NEUROSCIENCE

Huntington's Disease: Can Mice Lead the Way to Treatment?

(2011) Zachary R. Crook et al.   NEURON

Gene Therapy in Mouse Models of Huntington Disease

(2011) Amber L. Southwell et al.   NEUROSCIENTIST

Insufficiency of Electrolyte and Fluid Secretion by Pancreatic Ductal Cells Leads to Increased Patient Risk for Pancreatitis

(2010) Péter Hegyi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Transgenic expression of pancreatic secretory trypsin inhibitor-1 rescues SPINK3-deficient mice and restores a normal pancreatic phenotype

(2010) Joelle M.-J. Romac et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs

(2010) Dongshan Yang et al.   HUMAN MOLECULAR GENETICS

Contrasting gray and white matter changes in preclinical Huntington disease: An MRI study

(2010) D. Stoffers et al.   NEUROLOGY

Huntingtin Is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis

(2010) Juliette D. Godin et al.   NEURON

Deletion of the Huntingtin Polyglutamine Stretch Enhances Neuronal Autophagy and Longevity in Mice

(2010) Shuqiu Zheng et al.   PLoS Genetics

Sustained effects of nonallele-specificHuntingtinsilencing

(2009) Valérie Drouet et al.   ANNALS OF NEUROLOGY

The SPINK1 N34S variant is associated with acute pancreatitis

(2009) Derek A. OʼReilly et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

New Insights Into the Mechanisms of Pancreatitis

(2009) Herbert Y. Gaisano et al.   GASTROENTEROLOGY

Expression pattern of serine protease inhibitor kazal type 3 (Spink3) during mouse embryonic development

(2008) Jun Wang et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells

(2008) Daisuke Hashimoto et al.   JOURNAL OF CELL BIOLOGY

Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice

(2008) M. Gray et al.   JOURNAL OF NEUROSCIENCE

Rodent genetic models of Huntington disease

(2008) Mary Y. Heng et al.   NEUROBIOLOGY OF DISEASE

Role of genetic disorders in acute recurrent pancreatitis

(2008) Volker Keim   WORLD JOURNAL OF GASTROENTEROLOGY