Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation
出版年份 2016 全文链接
标题
Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 113, Issue 27, Pages E3892-E3900
出版商
Proceedings of the National Academy of Sciences
发表日期
2016-06-22
DOI
10.1073/pnas.1600582113
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
- (2015) Sidi Chen et al. CELL
- Adenovirus-Mediated Somatic Genome Editing ofPtenby CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses
- (2015) Dan Wang et al. HUMAN GENE THERAPY
- Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
- (2015) Silvana Konermann et al. NATURE
- Phase II study of targeted therapy with temozolomide in acute myeloid leukaemia and high-risk myelodysplastic syndrome patients pre-screened for low O6-methylguanine DNA methyltransferase expression
- (2014) Joseph M. Brandwein et al. BRITISH JOURNAL OF HAEMATOLOGY
- CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
- (2014) Randall J. Platt et al. CELL
- A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
- (2014) Marvin E. Tanenbaum et al. CELL
- Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
- (2014) Luke A. Gilbert et al. CELL
- High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells
- (2014) Yuexin Zhou et al. NATURE
- Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
- (2014) Chong Sun et al. NATURE
- Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
- (2014) Xuebing Wu et al. NATURE BIOTECHNOLOGY
- CRISPR-Cas systems for editing, regulating and targeting genomes
- (2014) Jeffry D Sander et al. NATURE BIOTECHNOLOGY
- Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
- (2014) Cem Kuscu et al. NATURE BIOTECHNOLOGY
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
- (2013) Luke A. Gilbert et al. CELL
- Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
- (2013) Albert W Cheng et al. CELL RESEARCH
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- RNAi screens in mice identify physiological regulators of oncogenic growth
- (2013) Slobodan Beronja et al. NATURE
- Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
- (2013) Hiroko Koike-Yusa et al. NATURE BIOTECHNOLOGY
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
- (2013) Prashant Mali et al. NATURE BIOTECHNOLOGY
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
- (2013) Pablo Perez-Pinera et al. NATURE METHODS
- CRISPR RNA–guided activation of endogenous human genes
- (2013) Morgan L Maeder et al. NATURE METHODS
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System
- (2013) Tim Wang et al. SCIENCE
- ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
- (2013) Thomas Gaj et al. TRENDS IN BIOTECHNOLOGY
- Mechanisms responsible for nilotinib resistance in human chronic myeloid leukemia cells and reversal of resistance
- (2012) Aylin Camgoz et al. LEUKEMIA & LYMPHOMA
- Tailored temozolomide therapy according to MGMT methylation status for elderly patients with acute myeloid leukemia
- (2011) Bruno C. Medeiros et al. AMERICAN JOURNAL OF HEMATOLOGY
- Genome Engineering With Zinc-Finger Nucleases
- (2011) Dana Carroll GENETICS
- Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
- (2011) Christof Fellmann et al. MOLECULAR CELL
- TALEs of genome targeting
- (2011) Jens Boch NATURE BIOTECHNOLOGY
- A public genome-scale lentiviral expression library of human ORFs
- (2011) Xiaoping Yang et al. NATURE METHODS
- CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute
- (2011) G Zoppoli et al. ONCOGENE
- Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC
- (2010) Alexa B. Turke et al. CANCER CELL
- p53 at a glance
- (2010) C. A. Brady et al. JOURNAL OF CELL SCIENCE
- Error-prone translesion synthesis mediates acquired chemoresistance
- (2010) K. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Suppression of Rev3, the catalytic subunit of Pol , sensitizes drug-resistant lung tumors to chemotherapy
- (2010) J. Doles et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blinded by the Light: The Growing Complexity of p53
- (2009) Karen H. Vousden et al. CELL
- Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2
- (2009) H Christian Reinhardt et al. CURRENT OPINION IN CELL BIOLOGY
- The completion of the Mammalian Gene Collection (MGC)
- (2009) et al. GENOME RESEARCH
- Hepatocyte Growth Factor Induces Gefitinib Resistance of Lung Adenocarcinoma with Epidermal Growth Factor Receptor-Activating Mutations
- (2008) S. Yano et al. CANCER RESEARCH
- Generations of sequencing technologies
- (2008) Erik Pettersson et al. GENOMICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now