Photodegradation of retinal bisretinoids in mouse models and implications for macular degeneration

HISTORY OF SUNLIGHT EXPOSURE IS A RISK FACTOR FOR AGE-RELATED MACULAR DEGENERATION

(2016) Tina Schick et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

The Effect of Light Deprivation in Patients With Stargardt Disease

(2015) Michel M. Teussink et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

The genetics of age-related macular degeneration (AMD) – Novel targets for designing treatment options?

(2015) Felix Grassmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition

(2015) Jilin Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium

(2014) M. M. Nociari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal

(2014) Faraz Quazi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fundus Autofluorescence and RPE Lipofuscin in Age-Related Macular Degeneration

(2014) Janet Sparrow et al.   Journal of Clinical Medicine

Is sunlight exposure a risk factor for age-related macular degeneration? A systematic review and meta-analysis

(2012) Guo-Yuan Sui et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Lipofuscin andN-Retinylidene-N-Retinylethanolamine (A2E) Accumulate in Retinal Pigment Epithelium in Absence of Light Exposure

(2012) Nicholas P. Boyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primary amines protect against retinal degeneration in mouse models of retinopathies

(2011) Akiko Maeda et al.   Nature Chemical Biology

The bisretinoids of retinal pigment epithelium

(2011) Janet R. Sparrow et al.   PROGRESS IN RETINAL AND EYE RESEARCH

The susceptibility of the retina to photochemical damage from visible light

(2011) Jennifer J. Hunter et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Enzymatic Degradation of A2E, a Retinal Pigment Epithelial Lipofuscin Bisretinoid

(2010) Yalin Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration

(2010) Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin

(2009) Vidyullatha Vasireddy et al.   EXPERIMENTAL EYE RESEARCH

Rdh12 Activity and Effects on Retinoid Processing in the Murine Retina

(2009) Jared D. Chrispell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Lipofuscin Bisretinoids Prominent in Human Retina and in a Model of Recessive Stargardt Disease

(2009) Yalin Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinal light damage: Mechanisms and protection

(2009) Daniel T. Organisciak et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Sunlight Exposure, Antioxidants, and Age-Related Macular Degeneration

(2008) Astrid E. Fletcher   ARCHIVES OF OPHTHALMOLOGY

Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance

(2008) Akiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY