Inability to activate Rac1-dependent forgetting contributes to behavioral inflexibility in mutants of multiple autism-risk genes

Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin

(2016) Sandeep K. Singh et al.   CELL

Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse

(2016) Karen A. Newell-Litwa   JOURNAL OF CELL BIOLOGY

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

(2016) Yuan Mei et al.   NATURE

La función ejecutiva está alterada en los trastornos del espectro autista, pero esta no correlaciona con la inteligencia

(2016) Jessica Merchán-Naranjo et al.   Revista de Psiquiatria y Salud Mental

From De Novo Mutations to Personalized Therapeutic Interventions in Autism

(2015) William M. Brandler et al.   Annual Review of Medicine

Genetic Epidemiology and Insights into Interactive Genetic and Environmental Effects in Autism Spectrum Disorders

(2015) Young Shin Kim et al.   BIOLOGICAL PSYCHIATRY

Neurexin-1 regulates sleep and synaptic plasticity in Drosophila melanogaster

(2015) Aoife Larkin et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Rho GTPase RAC1 at the Molecular Interface Between Genetic and Environmental Factors of Autism Spectrum Disorders

(2015) Fares Zeidán-Chuliá et al.   NEUROMOLECULAR MEDICINE

Dendritic spine dysgenesis in autism related disorders

(2015) Mary Phillips et al.   NEUROSCIENCE LETTERS

Synaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behavior

(2015) Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Demystifying cognitive flexibility: Implications for clinical and developmental neuroscience

(2015) Dina R. Dajani et al.   TRENDS IN NEUROSCIENCES

Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators

(2015) Lara J. Duffney et al.   Cell Reports

UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis

(2015) Jiandong Sun et al.   Cell Reports

Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 “Signalosome”

(2015) Sylwia Owczarek et al.   NEURAL PLASTICITY

Brain State Differentiation and Behavioral Inflexibility in Autism

(2014) Lucina Q. Uddin et al.   CEREBRAL CORTEX

The Implications of Brain Connectivity in the Neuropsychology of Autism

(2014) Jose O. Maximo et al.   NEUROPSYCHOLOGY REVIEW

CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome

(2014) Sabiha Abekhoukh et al.   Frontiers in Cellular Neuroscience

Environmental Chemical Exposures and Autism Spectrum Disorders: A Review of the Epidemiological Evidence

(2014) Amy E. Kalkbrenner et al.   Current Problems in Pediatric and Adolescent Health Care

Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila

(2013) S. H. Friedman et al.   Disease Models & Mechanisms

TSC1/2 regulates intestinal stem cell maintenance and lineage differentiation through Rheb-TORC1-S6K but independently of nutritional status or Notch regulation

(2013) Z. Quan et al.   JOURNAL OF CELL SCIENCE

Drosophila Neuroligin 4 Regulates Sleep through Modulating GABA Transmission

(2013) Y. Li et al.   JOURNAL OF NEUROSCIENCE

Activity-dependent neuronal signalling and autism spectrum disorder

(2013) Daniel H. Ebert et al.   NATURE

Exploring the Multifactorial Nature of Autism Through Computational Systems Biology: Calcium and the Rho GTPase RAC1 Under the Spotlight

(2013) Fares Zeidán-Chuliá et al.   NEUROMOLECULAR MEDICINE

Reduced behavioral flexibility in autism spectrum disorders.

(2013) Anna-Maria D'Cruz et al.   NEUROPSYCHOLOGY

TSC1 Controls Distribution of Actin Fibers through Its Effect on Function of Rho Family of Small GTPases and Regulates Cell Migration and Polarity

(2013) Maki Ohsawa et al.   PLoS One

Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses

(2012) James P. Clement et al.   CELL

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

(2012) Nien-Pei Tsai et al.   CELL

A Permissive Role of Mushroom Body α/β Core Neurons in Long-Term Memory Consolidation in Drosophila

(2012) Cheng Huang et al.   CURRENT BIOLOGY

Autism-related deficits via dysregulated eIF4E-dependent translational control

(2012) Christos G. Gkogkas et al.   NATURE

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

Autism as a neural systems disorder: A theory of frontal-posterior underconnectivity

(2012) Marcel Adam Just et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

SnapShot: Autism and the Synapse

(2011) João Peça et al.   CELL

Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

(2011) Brian J O'Roak et al.   NATURE GENETICS

Genome structural variation discovery and genotyping

(2011) Can Alkan et al.   NATURE REVIEWS GENETICS

Neurexin-Neuroligin Transsynaptic Interaction Mediates Learning-Related Synaptic Remodeling and Long-Term Facilitation in Aplysia

(2011) Yun-Beom Choi et al.   NEURON

Forgetting Is Regulated through Rac Activity in Drosophila

(2010) Yichun Shuai et al.   CELL

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

(2010) Paul L. Greer et al.   CELL

De novo rates and selection of large copy number variation

(2010) A. Itsara et al.   GENOME RESEARCH

Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development

(2009) Blythe A. Corbett et al.   PSYCHIATRY RESEARCH

The paradox of cognitive flexibility in autism

(2009) Hilde M. Geurts et al.   TRENDS IN COGNITIVE SCIENCES

Disruption of Neurexin 1 Associated with Autism Spectrum Disorder

(2008) Hyung-Goo Kim et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Autistic Neuron: Troubled Translation?

(2008) Raymond J. Kelleher et al.   CELL

Spatial and Temporal Control of Gene Expression in Drosophila Using the Inducible GeneSwitch GAL4 System. I. Screen for Larval Nervous System Drivers

(2008) Louise Nicholson et al.   GENETICS

The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branches

(2008) Y. Lu et al.   HUMAN MOLECULAR GENETICS

Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory

(2008) François V Bolduc et al.   NATURE NEUROSCIENCE

Advances in autism genetics: on the threshold of a new neurobiology

(2008) Brett S. Abrahams et al.   NATURE REVIEWS GENETICS

A Drosophila model for Angelman syndrome

(2008) Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA