Beneficial effects of IL-37 after spinal cord injury in mice

IL-37 requires IL-18Rα and SIGIRR/IL-1R8 to diminish allergic airway inflammation in mice

(2015) L. Lunding et al.   ALLERGY

IL-37 inhibits IL-18-induced tubular epithelial cell expression of pro-inflammatory cytokines and renal ischemia-reperfusion injury

(2015) Yunbo Yang et al.   KIDNEY INTERNATIONAL

IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction

(2015) Claudia A Nold-Petry et al.   NATURE IMMUNOLOGY

Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8

(2015) Suzhao Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroimmunology of traumatic spinal cord injury: A brief history and overview

(2014) Phillip G. Popovich   EXPERIMENTAL NEUROLOGY

High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury

(2014) Teresa A. Evans et al.   EXPERIMENTAL NEUROLOGY

Immunobiology of IL-37: mechanism of action and clinical perspectives

(2014) Shannon Quirk et al.   Expert Review of Clinical Immunology

IL-37 Ameliorates the Inflammatory Process in Psoriasis by Suppressing Proinflammatory Cytokine Production

(2014) X. Teng et al.   JOURNAL OF IMMUNOLOGY

IL-37 inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells of patients with systemic lupus erythematosus: its correlation with disease activity

(2014) Liang Ye et al.   Journal of Translational Medicine

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells

(2014) Yuchun Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

(2014) A.-M. Bulau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central Nervous System Regenerative Failure: Role of Oligodendrocytes, Astrocytes, and Microglia

(2014) Jerry Silver et al.   Cold Spring Harbor Perspectives in Biology

IL-37 protects against obesity-induced inflammation and insulin resistance

(2014) Dov B. Ballak et al.   Nature Communications

IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

(2014) Silvia Moretti et al.   PLoS Pathogens

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

Interleukin-37

(2013) Charles A. Dinarello et al.   SEMINARS IN IMMUNOLOGY

Beneficial Effects of  B-Crystallin in Spinal Cord Contusion Injury

(2012) A. Klopstein et al.   JOURNAL OF NEUROSCIENCE

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Phospholipase A2 superfamily members play divergent roles after spinal cord injury

(2011) Rubèn López-Vales et al.   FASEB JOURNAL

Interleukin 37 expression protects mice from colitis

(2011) E. N. McNamee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Expression of Interleukin-37 Reduces Local and Systemic Inflammation in Concanavalin A-Induced Hepatitis

(2011) Ana-Maria Bulau et al.   TheScientificWorldJOURNAL

IL-37 is a fundamental inhibitor of innate immunity

(2010) Marcel F Nold et al.   NATURE IMMUNOLOGY

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice

(2009) Elizabeth J. Fry et al.   GLIA

Another Barrier to Regeneration in the CNS: Activated Macrophages Induce Extensive Retraction of Dystrophic Axons through Direct Physical Interactions

(2008) K. P. Horn et al.   JOURNAL OF NEUROSCIENCE

Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry

(2008) David P. Stirling et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon

(2008) James W. Rowland et al.   Neurosurgical Focus