DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression

NF-κB-dependent DNA damage-signaling differentially regulates DNA double-strand break repair mechanisms in immature and mature human hematopoietic cells

(2015) D Kraft et al.   LEUKEMIA

HLTF’s Ancient HIRAN Domain Binds 3′ DNA Ends to Drive Replication Fork Reversal

(2015) Andrew C. Kile et al.   MOLECULAR CELL

Modulation of the poly (ADP-ribose) polymerase inhibitor response and DNA recombination in breast cancer cells by drugs affecting endogenous wild-type p53

(2014) Ivanildce Cristiane Ireno et al.   CARCINOGENESIS

Replicative DNA polymerase mutations in cancer

(2014) Ellen Heitzer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Tolerating DNA damage during eukaryotic chromosome replication

(2014) Irene Saugar et al.   EXPERIMENTAL CELL RESEARCH

The MRE11 complex: An important source of stress relief

(2014) Katrin Rein et al.   EXPERIMENTAL CELL RESEARCH

ATR phosphorylates SMARCAL1 to prevent replication fork collapse

(2013) F. B. Couch et al.   GENES & DEVELOPMENT

Replication Dynamics: Biases and Robustness of DNA Fiber Analysis

(2013) Hervé Técher et al.   JOURNAL OF MOLECULAR BIOLOGY

Strand invasion by HLTF as a mechanism for template switch in fork rescue

(2013) Peter Burkovics et al.   NUCLEIC ACIDS RESEARCH

Structure of human DNA polymerase iota and the mechanism of DNA synthesis

(2012) A. V. Makarova et al.   BIOCHEMISTRY-MOSCOW

ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response

(2012) R. Weston et al.   GENES & DEVELOPMENT

SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication

(2012) R. Betous et al.   GENES & DEVELOPMENT

Finally, Polyubiquitinated PCNA Gets Recognized

(2012) Michelle K. Zeman et al.   MOLECULAR CELL

The HARP-like Domain-Containing Protein AH2/ZRANB3 Binds to PCNA and Participates in Cellular Response to Replication Stress

(2012) Jingsong Yuan et al.   MOLECULAR CELL

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress

(2012) Alberto Ciccia et al.   MOLECULAR CELL

Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA

(2012) J. Speroni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis

(2011) Zvi Livneh et al.   CELL CYCLE

DNA replication and repair bypass machines

(2011) Ulrich Hübscher et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Brca2, Rad51 and Mre11: Performing balancing acts on replication forks

(2011) Vincenzo Costanzo   DNA REPAIR

Timing and spacing of ubiquitin-dependent DNA damage bypass

(2011) Helle D. Ulrich   FEBS LETTERS

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

(2011) A. V. Nimonkar et al.   GENES & DEVELOPMENT

Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI

(2011) George-Lucian Moldovan et al.   MOLECULAR CELL

Coordinated protein and DNA remodeling by human HLTF on stalled replication fork

(2011) Y. J. Achar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein

(2010) Jinwoo Ahn et al.   CELL CYCLE

The interaction of p53 with 3'-terminal mismatched DNA

(2010) Mary Bakhanashvili et al.   CELL CYCLE

A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal

(2010) Michael Milyavsky et al.   Cell Stem Cell

Role of yeast Rad5 and its human orthologs, HLTF and SHPRH in DNA damage tolerance

(2010) Ildiko Unk et al.   DNA REPAIR

Pathways of mammalian replication fork restart

(2010) Eva Petermann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51

(2009) Aura Carreira et al.   CELL

Y-family DNA polymerases in mammalian cells

(2009) Caixia Guo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Insights into the cellular role of enigmatic DNA polymerase ι

(2009) Antonio E. Vidal et al.   DNA REPAIR

Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress

(2009) V. M. Vassin et al.   JOURNAL OF CELL SCIENCE

Role of Double-Stranded DNA Translocase Activity of Human HLTF in Replication of Damaged DNA

(2009) A. Blastyak et al.   MOLECULAR AND CELLULAR BIOLOGY

Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: Mechanistic insights

(2009) Larry H. Thompson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

p53 in mitochondria enhances the accuracy of DNA synthesis

(2008) M Bakhanashvili et al.   CELL DEATH AND DIFFERENTIATION

A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex

(2008) Aude Dupré et al.   Nature Chemical Biology

Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants

(2008) A. Restle et al.   NUCLEIC ACIDS RESEARCH