Article
Otorhinolaryngology
Katherine Tashman, Elizabeth A. Noyes, Chloe B. Warinner, Joseph Ogbonna, Ernest Gomez, Scharukh M. Jalisi
Summary: The safety-net status of hospitals is associated with higher mortality index and cost in geriatric head and neck cancer patients. Medium case volume and safety-net status together predict higher mortality index.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2023)
Article
Medicine, Research & Experimental
Chloe B. Warinner, Regan W. Bergmark, Rosh Sethi, Eleni M. Rettig
Summary: Cancer-related activity limitations are more common among HNC survivors compared to survivors of other cancers, especially affecting socioeconomically disadvantaged survivors.
Article
Medicine, Research & Experimental
Nicholas R. Lenze, Douglas Farquhar, Siddharth Sheth, Jose P. Zevallos, Jeffrey Blumberg, Catherine Lumley, Samip Patel, Trevor Hackman, Mark C. Weissler, Wendell G. Yarbrough, Adam M. Zanation, Andrew F. Olshan
Summary: A study of HPV-negative head and neck squamous cell carcinoma patients found that racial disparities in diagnosis and survival are primarily influenced by socioeconomic status, with low SES serving as a target for interventions aimed at mitigating these disparities.
Article
Otorhinolaryngology
Shreya P. Ramkumar, Arun Bhardwaj, Amila Patel, Krishnamoorthy Seetharaman, Amanda Christman, Ninad Amondikar, Dina K. Abouelella, Adnan S. Hussaini, Justin M. Barnes, Eric Adjei Boakye, Tammara L. Watts, Nosayaba Osazuwa-Peters
Summary: This retrospective cohort study aimed to characterize the clinical and nonclinical factors associated with the receipt of immunotherapy among older patients with head and neck squamous cell carcinoma (HNSCC). The study found that White patients with HNSCC were more likely to receive immunotherapy, while age, sex, and smoking history did not have a significant impact on the odds of receiving immunotherapy.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2023)
Article
Otorhinolaryngology
Baruch Weizman, Nili Golan, Ohad Ronen
Summary: The study aimed to assess the survival outcomes of head and neck cancer patients by socioeconomic status. It found that patients from higher socioeconomic areas had better survival rates, with age over 65 and low socioeconomic status being correlated with inferior overall survival.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Article
Oncology
Nadia Mezghani, Alexandria Yao, Daria Vasilyeva, Nicole Kaplan, Austin Shackelford, Angela Yoon, Elizabeth Phillipone, Sunil Dubey, Gary K. Schwartz, Alison M. Taylor, Fatemeh Momen-Heravi
Summary: The purpose of this study was to understand the molecular biomarkers and signatures of head and neck cancer (HNC) among Black patients and identify molecular changes associated with HNC disparities. The study identified molecular subtypes and genomic changes in HNC samples from Black and White patients, as well as their clinical outcomes. The findings showed that Black patients had more aggressive tumor types, higher frequencies of certain gene mutations, and poorer survival outcomes. The study suggests that these molecular features could be used for more targeted screening, diagnosis, and treatment to improve health outcomes.
CLINICAL CANCER RESEARCH
(2023)
Article
Otorhinolaryngology
Lauren A. Lawrence, Mitchell L. Heuermann, Pardis Javadi, Arun Sharma
Summary: This study examined the relationship among rurality, socioeconomic status, and patient/tumor characteristics in head and neck cancer patients. It found that rural residence was associated with lower SES, and T and N stages were related to rurality. Additionally, higher educational status was linked to oropharyngeal cancer.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Article
Oncology
Richard S. Hoehn, Caroline J. Rieser, Sharon Winters, Lauren Stitt, Melissa E. Hogg, David L. Bartlett, Kenneth K. Lee, Alessandro Paniccia, James P. Ohr, Vikram C. Gorantla, Anuradha Krishnamurthy, John C. Rhee, Nathan Bahary, Adam C. Olson, Steve Burton, Susannah G. Ellsworth, Adam Slivka, Kevin McGrath, Asif Khalid, Kenneth Fasanella, Jennifer Chennat, Randal E. Brand, Rohit Das, Ritu Sarkaria, Aatur D. Singhi, Herbert J. Zeh, Amer H. Zureikat
Summary: National studies have shown disparities in treatment and survival of pancreatic cancer patients based on socioeconomic status. This study found that low-SES patients had poorer outcomes compared to high-SES patients outside of the MDC, but these differences were eliminated within the MDC setting. Low SES was associated with inferior survival for non-MDC patients, but not for MDC patients.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Angela L. Mazul, Akash N. Naik, Kevin Y. Zhan, Katelyn O. Stepan, Matthew O. Old, Stephen Y. Kang, Erik R. Nakken, Sidharth Puram
Summary: The study found that gender and race have an impact on the overall survival of head and neck squamous cell carcinoma, with female non-oropharyngeal HNSCC patients having better five-year overall survival compared to males. Black females had poorer survival rates compared to White and Hispanic males, with oral cavity cancer being more common among Hispanic and White females.
Article
Oncology
Aurora Gaeta, Marta Tagliabue, Oriana D'Ecclesiis, Lavinia Ghiani, Paolo Maugeri, Rita De Berardinis, Camilla Veneri, Camilla Gaiaschi, Marina Cacace, Luciano D'Andrea, Mohssen Ansarin, Sara Gandini, Susanna Chiocca
Summary: We analyzed the inclusion of sex and/or gender in Head and Neck Cancer clinical studies. Only 5% of studies mentioned sex and/or gender as an analytical variable, with observational studies treating it more than interventional studies. Studies with a sample size greater than 100 and including HPV status were more likely to mention sex and/or gender. In oral cavity-larynx-oropharynx studies, HPV was only mentioned in 18% of cases. There is a need to systematically include sex and/or gender in study design to better understand disease differences and incorporate biological and cultural factors into science and medicine.
NPJ PRECISION ONCOLOGY
(2023)
Article
Oncology
Ahmed Bedir, Semaw Ferede Abera, Ljupcho Efremov, Lamiaa Hassan, Dirk Vordermark, Daniel Medenwald
Summary: This study confirms survival disparities between affluent and deprived HNC patients in Germany. Although data limitations exist, the results suggest that eliminating differences in stage at diagnosis within six months after HNC diagnosis could reduce survival inequalities.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2021)
Article
Otorhinolaryngology
Tatenda Chakoma, Peter K. Moon, Oyomoare L. Osazuwa-Peters, Uchechukwu C. Megwalu, Nosayaba Osazuwa-Peters
Summary: This study investigated the association between HPV tumor status and suicide risk among patients with head and neck cancer. The results showed that HPV-positive cancers had a slightly higher risk of suicide compared to HPV-negative cancers, but this association was no longer significant in the fully adjusted model. However, the relationship between HPV status and suicide risk in oropharyngeal cancer patients remains uncertain due to the wide confidence interval.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2023)
Article
Medicine, General & Internal
Kekoa Taparra, Vera Qu, Erqi Pollom
Summary: This study compared comorbidity burden and survival among different ethnic groups with cancer. Results showed that Native Hawaiian and other Pacific Islander patients had the highest comorbidity burden and inferior survival outcomes compared to Asian and White patients, supporting the importance of disaggregating these groups in cancer studies.
Article
Medicine, Research & Experimental
Tooba Alwani, Jennifer N. Shehan, Jessica LeClair, Taylor F. Mahoney, Pratima Agarwal, Salil T. Chaudhry, Judy J. Wang, Jacob P. Noordzij, Lauren F. Tracy, Heather A. Edwards, Gregory Grillone, Andrew R. Salama, Scharukh M. Jalisi, Anand K. Devaiah
Summary: This study explores the impact of social determinants of health on follow-up care in head and neck cancers. Factors such as income, primary language, country of birth, race/ethnicity, insurance status, and markers of educational attainment do not appear to influence follow-up care at a safety-net, tertiary care institution, but distance from hospital remains a significant contributor to care disparities.
Article
Medicine, General & Internal
Jeffrey M. Howard, Karabi Nandy, Solomon L. Woldu, Vitaly Margulis
Summary: This study revealed significant disparities in treatment decision-making for patients with kidney cancer, with increased rates of non-guideline-based treatment for women and Black and Hispanic patients. Further research into the mechanisms underlying these disparities is warranted.
Article
Health Care Sciences & Services
Jennifer Meddings, M. Todd Greene, David Ratz, Jessica Ameling, Karen E. Fowler, Andrew J. Rolle, Louella Hung, Sue Collier, Sanjay Saint
BMJ QUALITY & SAFETY
(2020)
Article
Medicine, General & Internal
Akihiko Saitoh, Kiyomi Sato, Yoko Magara, Kakuei Osaki, Kiyoko Narita, Kumiko Shioiri, Karen E. Fowler, David Ratz, Sanjay Saint
JOURNAL OF HOSPITAL MEDICINE
(2020)
Article
Public, Environmental & Occupational Health
Karen E. Fowler, Sarah L. Krein, David Ratz, Debbie Zawol, Sanjay Saint
Summary: The study found that a quality improvement intervention successfully reduced urethral catheter use in the long term at a Veterans Affairs hospital, with continued decrease in utilization and unchanged appropriateness of use.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
M. Todd Greene, Sarah L. Krein, Anita Huis, Marlies Hulscher, Hugo Sax, Fumie Sakamoto, Tomoko Sakihama, Yasuharu Tokuda, Karen E. Fowler, Sanjay Saint
Summary: The study assessed the regular use of evidence-based practices in acute care hospitals across the US, Netherlands, Switzerland, and Japan. Most hospitals adopted recommended practices, but there were opportunities for reducing hospital-acquired infection risks in all four countries. Some prevention practices were used less frequently in Swiss and Japanese hospitals, and surveillance systems were lacking in Dutch, Swiss, and Japanese hospitals.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Article
Infectious Diseases
Kohta Katayama, Jennifer Meddings, Sanjay Saint, Karen E. Fowler, David Ratz, Yasuaki Tagashira, Yumi Kawamura, Tatsuya Fujikawa, Sho Nishiguchi, Naomi Kayauchi, Nobumasa Takagaki, Yasuharu Tokuda, Akira Kuriyama
Summary: This study investigated the prevalence and appropriateness of indwelling urinary catheters, and the incidence of catheter-associated urinary tract infection (CAUTI) in non-intensive care unit (non-ICU) wards in Japanese hospitals. The study found that the mean prevalence of catheter use was 13%, the mean incidence of CAUTI was 9.86 per 1000 catheter-days, and approximately 66% of the catheter days had appropriate indications for use.
BMC INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Pariyamon Thaprawat, Michael Todd Greene, Sanjay Saint, Nongyao Kasatpibal, Karen E. Fowler, Anucha Apisarnthanarak
Summary: This study assessed infection prevention practices in Thai hospitals for CAUTI, CLABSI, and VAP and compared them to previous results. The findings showed improvement in some prevention practices, but many areas still need improvement. COVID-19 has presented challenges such as staff shortages and financial hardships. The study emphasizes the need for national strategic support to prevent infections and promote healthcare worker well-being during the pandemic.
AMERICAN JOURNAL OF INFECTION CONTROL
(2022)
Article
Health Care Sciences & Services
Richard J. J. Schildhouse, Ashwin Gupta, M. Todd Greene, Karen E. E. Fowler, David Ratz, Mark S. S. Hausman, Sanjay Saint
Summary: Based on a national survey conducted in the US, this study compares the impact of resource shortages and response to the COVID-19 pandemic between Veterans Affairs (VA) and non-federal hospitals. The results show that VA hospitals had advantages in expanding bed capacity, retaining staff, mitigating supply shortages, and avoiding financial hardship compared to non-federal hospitals. The findings suggest that non-federal hospitals can learn from the VA's structure to better prepare for future system shocks.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Sanjay Saint, M. Todd Greene, Sarah L. L. Krein, Karen E. E. Fowler, Kathleen A. A. Linder, David Ratz, Jennifer Meddings
Summary: This study aimed to investigate the changes in device-associated infection prevention practices during the COVID-19 pandemic. Data collected mid-pandemic were used to assess the use of several infection prevention practices and compare them with historical data. The results showed that the use of preventive practices for CLABSI and VAE continued to increase or plateau, while the use of preventive practices for CAUTI decreased.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Heather M. Gilmartin, Sanjay Saint, David Ratz, Kristin Chrouser, Karen E. Fowler, M. Todd Greene
Summary: This study surveyed infection preventionists' perceptions of hospital leadership support for infection prevention and control programs during the COVID-19 pandemic, as well as their relationships with burnout, psychological safety, and safety climate. The results showed an association between strong hospital leadership support and lower burnout, higher perceptions of psychological safety, and a better safety climate. These findings contribute to enhancing the well-being of infection preventionists and improving the quality and safety of patient care.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Shipra Saini, Namita Bindal, Brajesh Kumar Kaushik
Summary: Using first-principle calculations, the authors observe variations in magnetic anisotropy energy and other magnetic properties for transition metal (TM) doped bismuth monolayer. The Mn-doped bismuthene exhibits half-metallicity with higher magnetic moment and magnetic anisotropy energy compared to Fe-doped and Ti-doped systems. The half-metal Mn-Bi can induce half-metallicity in CrI3 through charge transfer, making it the most favorable doped system for spintronic device development in Mn-Bi/CrI3 van der Waals heterostructure.
IEEE OPEN JOURNAL OF NANOTECHNOLOGY
(2023)
Article
Medicine, General & Internal
Ashwin Gupta, Martha Quinn, Sanjay Saint, Richard Lewis, Karen E. Fowler, Suzanne Winter, Vineet Chopra
Summary: This study investigated the diagnostic thinking process of hospital medicine physicians when evaluating patients, using a case-based simulation. The results showed significant heterogeneity in both differential diagnoses and clinical reasoning among the participants. Structured approaches and debiasing strategies were found to be helpful in promoting diagnostic accuracy.
Article
Medicine, General & Internal
Valerie M. Vaughn, Sanjay Saint, M. Todd Greene, David Ratz, Karen E. Fowler, Payal K. Patel, Sarah L. Krein
Article
Medicine, General & Internal
Sanjay Saint, Sarah L. Krein, Karen E. Fowler, John Colozzi, David Ratz, Erica Lescinskas, Kristin Chrouser, Barbara W. Trautner
JOURNAL OF HOSPITAL MEDICINE
(2020)
Meeting Abstract
Urology & Nephrology
Kristin Chrouser, Ted Skolarus, Karen Fowler, Jason Mann, Steven Burstein, Jennifer Meddings
NEUROUROLOGY AND URODYNAMICS
(2020)
Article
Health Care Sciences & Services
Martha Quinn, Jessica M. Ameling, Jane Forman, Sarah L. Krein, Milisa Manojlovich, Karen E. Fowler, Elizabeth A. King, Jennifer Meddings
JOINT COMMISSION JOURNAL ON QUALITY AND PATIENT SAFETY
(2020)