Article
Agriculture, Dairy & Animal Science
Katsiaryna Lundova, Jan Matousek, Vlastimil Stejskal
Summary: The study found that exposing fish to a regimen of 48 hours of natural ambient photoperiod alternating with 24 hours of constant light effectively delayed gonad development and puberty onset in brook trout, leading to increased somatic growth.
Editorial Material
Microbiology
T. Jarrod Smith, Caitlin H. Kowalski, Karen Guillemin
Summary: Microbes are able to manipulate hosts cleverly for their own benefit, but their actions are not always completely undetected. This study focuses on how Schistosoma mansoni eggs coordinate macrophage behaviors to promote the efficient transmission of mature eggs while keeping immature eggs hidden in plain sight.
CELL HOST & MICROBE
(2021)
Article
Environmental Sciences
Evan C. Boone, Mark J. Brouder, Henry R. Quinlan
Summary: The study highlights the successful recovery of an adfluvial brook trout population in Washington Harbor, Isle Royale National Park, Lake Superior following the implementation of catch-and-release regulations in 2004. The research shows an increase in brook trout abundance and distribution in Washington Harbor since the late 1990s and early 2000s, likely attributed to protective regulations and improved water flows in recent years. Annual tag detection rates of Washington Harbor brook trout in Washington Creek ranged from 25% in 2009 to 100% in 2011 and 2013, with an average of 60.7% throughout the study period.
JOURNAL OF GREAT LAKES RESEARCH
(2021)
Review
Immunology
Aaron M. T. Barnes, Kristi L. Frank, Gary M. Dunny
Summary: Enterococcus faecalis is a major opportunistic bacterial pathogen that can form stable biofilm colonies on undamaged surfaces, potentially allowing for undetected infection in asymptomatic individuals and serving as a reservoir for later clinical endocarditis. This ability to persist and hide in plain sight may contribute to the increasing clinical relevance of this pathogen in various host tissues.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Zoology
R. Sliger, G. D. Grossman
Summary: The study successfully predicted the holding velocity of brook charr using the optimal foraging model, suggesting that NEI maximization is a key factor affecting their habitat choice. The results also support the general usefulness of this model in describing the behavior of stream fishes.
JOURNAL OF ZOOLOGY
(2021)
Review
Cell Biology
Chandler Marrs, Derrick Lonsdale
Summary: Thiamine, also known as vitamin B1, is essential for mitochondrial energetics and energy production, but deficiency is common in modern life and poses significant health risks.
Review
Genetics & Heredity
Stewart Shuman
Summary: This review discusses the discovery, mechanisms, and physiology of purposeful RNA break repair, highlighting several repair pathways, including tRNA restriction-repair and tRNA splicing, in which genetics has played a key role in elucidation.
ANNUAL REVIEW OF GENETICS
(2023)
Review
Physiology
Elizabeth A. Stewart, Romana A. Nowak
Summary: Uterine fibroids are a common condition in women that can cause serious health issues. The mechanisms behind their growth and development are currently not well understood and require further research.
Review
Anesthesiology
Marc A. Russo, Ralf Baron, Anthony H. Dickenson, Kai-Uwe Kern, Danielle M. Santarelli
Summary: Ambroxol is a versatile drug with multiple therapeutic actions, including mucoactive, secretolytic, anti-inflammatory, antioxidant, and local anesthetic properties. It has a long history of use in respiratory diseases and has shown efficacy in relieving sore throat. Recent research has focused on its potential for neuropathic pain treatment, despite slow progress. Ambroxol is an inhibitor of Na(v)1.8, an important player in neuropathic pain, and Na(v)1.7, a promising target for chronic pain treatment. This review discusses its analgesic mechanisms, synergistic properties, preclinical and clinical results in managing persistent pain and neuropathic pain symptoms. It is a safe drug with extensive data, encouraging further investigation for repurposing, and urging the pharmaceutical industry to develop optimized formulations for neuropathic pain.
Article
Plant Sciences
Attila Matis, Tamas Malkocs, Thomas Kuhn, Levente Laczko, Ivan Moysiyenko, Anna Szabo, Alexandru S. Badarau, Gabor Sramko
Summary: This study used morphometric and phylogenomic analyses and found an overlooked species of Salvia. The new species differs from closely related taxa in floral structure, habitat preference, and distribution.
Article
Engineering, Manufacturing
Jiaru Bai, H. Sebastian Heese, Manish Tripathy
Summary: Many on-demand service platforms face potential collusion among service providers, who strategically collude to induce artificial supply shortages. This study explores pricing policies that can mitigate the impact of potential collusion, including a bonus pricing policy and an optimal pricing policy. Both policies incentivize providers to offer their services and can effectively alleviate the negative effects of collusion. It’s important for platforms to consider the risk of collusion when designing pricing policies to avoid significant losses.
PRODUCTION AND OPERATIONS MANAGEMENT
(2023)
Article
Neurosciences
Laramie Duncan, Karl Deisseroth
Summary: Psychiatric diseases are influenced by genetics, and genome-wide association studies have successfully linked hundreds of genetic loci to psychiatric disorders. This study focuses on four specific phenotypes related to psychiatry and proposes an exploratory workflow, from GWAS screening to causal testing in animal models, leading to the development of new therapies in humans.
NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Marcus J. C. Long, Mahdi Assari, Yimon Aye
Summary: This article discusses the significance of hidden variables in experiments, particularly in the field of modern chemical biology. Hidden variables are commonly introduced during experiments and can have an impact on experimental design and data interpretation. It is important to account for hidden variables in order to improve the development of new methods.
ACS CHEMICAL BIOLOGY
(2022)
Article
Biodiversity Conservation
Gabriella R. M. Leighton, Jacqueline M. Bishop, Justin Merondun, Deborah J. Winterton, M. Justin O'Riain, Laurel E. K. Serieys
Summary: This study examined the resource selection of caracals in and around Cape Town, South Africa, at varying levels of urbanization. The results showed that caracals living in the urban-dominated region preferred the urban edge for foraging, while those in the wildland-dominated region avoided it. Adults had a stronger preference for urban edge foraging compared to juveniles, potentially competing for resources and excluding them. The study also highlighted the risk mitigation strategies of caracals in urban areas, showing their adaptability in coexisting with humans despite the higher risks involved.
ANIMAL CONSERVATION
(2022)
Article
Fisheries
Emily R. Lechner, Erin M. C. Stewart, Chris C. Wilson, Graham D. Raby
Summary: This study examined the impact of thermal acclimation on thermal tolerance in brook trout embryos. The results showed that warm acclimation can increase the upper thermal tolerance of the embryos, although the variability of CTmax was higher than typical for other salmonids.
JOURNAL OF FISH BIOLOGY
(2023)
Article
Environmental Sciences
Mark S. Castro, Robert H. Hilderbrand, Morgan Kaumeyer
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Vikram E. Chhatre, Luke M. Evans, Stephen P. DiFazio, Stephen R. Keller
Article
Environmental Sciences
Mark S. Castro, Morgan Kaumeyer, Robert H. Hilderbrand
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2019)
Article
Plant Sciences
Karl C. Fetter, Sven Eberhardt, Rich S. Barclay, Scott Wing, Stephen R. Keller
Article
Biodiversity Conservation
Brittany M. Verrico, Jeremy Weiland, Timothy D. Perkins, Brian Beckage, Stephen R. Keller
DIVERSITY AND DISTRIBUTIONS
(2020)
Article
Evolutionary Biology
Thibaut Capblancq, John R. Butnor, Sonia Deyoung, Ethan Thibault, Helena Munson, David M. Nelson, Matthew C. Fitzpatrick, Stephen R. Keller
EVOLUTIONARY APPLICATIONS
(2020)
Article
Multidisciplinary Sciences
Robert H. Hilderbrand, Stephen R. Keller, Sarah M. Laperriere, Alyson E. Santoro, Jason Cessna, Regina Trott
Article
Environmental Sciences
Andrew V. Gougherty, Stephen R. Keller, Matthew C. Fitzpatrick
Summary: Understanding the potential disruption of climate adaptation in forest tree species can help identify the greatest risks posed by climate change, especially at the edges of species ranges. The study indicates that populations may face risks from shifting climates due to maladaptation and limited migration options, particularly in regions with novel genotype-climate associations.
NATURE CLIMATE CHANGE
(2021)
Article
Biochemistry & Molecular Biology
Matthew C. Fitzpatrick, Vikram E. Chhatre, Raju Y. Soolanayakanahally, Stephen R. Keller
Summary: The study evaluates the ability of genomic offsets derived from Gradient Forests to predict organismal responses to environmental change and explores the use of GF for identifying candidate SNPs. Results suggest that genetic offsets serve as a first order estimate of expected maladaptation of populations to rapid environmental change, and GF may have some promise as a method for identifying candidate SNPs. Additionally, populations with larger predicted genetic offsets performed worse in common garden experiments, indicating the potential utility of genetic offsets in predicting performance under changing environmental conditions.
MOLECULAR ECOLOGY RESOURCES
(2021)
Article
Ecology
Karl C. Fetter, David M. Nelson, Stephen R. Keller
Summary: The study highlights the importance of stomata in determining growth-defense strategies in organisms susceptible to foliar pathogens. Hybridization studies offer insights into trait evolution before selection removes maladaptive trait variation.
Article
Evolutionary Biology
Aki Jarl Laruson, Matthew C. Fitzpatrick, Stephen R. Keller, Benjamin C. Haller, Katie E. Lotterhos
Summary: This study explores the relationship between GF Offset and fitness in the Gradient Forest algorithm, and finds that GF Offset is correlated with fitness offsets under both single locus and polygenic architectures. However, neutral demography, genomic architecture, and the nature of the adaptive environment can confound this relationship.
EVOLUTIONARY APPLICATIONS
(2022)
Article
Plant Sciences
Thibaut Capblancq, Susanne Lachmuth, Matthew C. Fitzpatrick, Stephen R. Keller
Summary: This study combines genomic methods and common gardens to investigate local adaptation in red spruce. It identifies environmental gradients and loci involved in climate adaptation and uncovers phenotypic evidence of local adaptation to climate.
Review
Ecology
Robert H. Hilderbrand, Ted Bambakidis, Byron C. Crump
Summary: The goods and services provided by riverine systems are vital for humanity, but these systems are degrading worldwide despite restoration efforts. Designing restorations to promote microbial communities could enhance restoration effectiveness. Focusing on microbial diversity and function can improve resilience and assess restoration suitability. Advancements in next-generation sequencing allow the use of microbial 'omics techniques to assess river ecological conditions and advance assessment capabilities.
Article
Ecology
Karl C. Fetter, Stephen R. Keller
Summary: This study investigated disease dynamics in hybrid and non-hybrid populations using quantitative genetic and population genomic methods. The researchers found that stomatal patterning traits were highly predictive of disease risk and candidate genes for stomatal and disease resistance mapped to the same genomic regions and experienced positive selection.
ECOLOGY AND EVOLUTION
(2023)
Article
Plant Sciences
Ethan Thibault, Raju Soolanayakanahally, Stephen R. Keller
AMERICAN JOURNAL OF BOTANY
(2020)