The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments

Selective Na+/Ca2+exchanger inhibition prevents Ca2+overload-induced triggered arrhythmias

(2014) Norbert Nagy et al.   BRITISH JOURNAL OF PHARMACOLOGY

ORM-10103, a novel specific inhibitor of the Na+/Ca2+exchanger, decreases early and delayed afterdepolarizations in the canine heart

(2013) N Jost et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Effect of SN-6, a Novel Sodium-Calcium Exchange Inhibitor, on Contractility and Calcium Handling in Isolated Failing Rat Ventricular Myocytes

(2013) Ajay Gandhi et al.   Cardiovascular Therapeutics

Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs

(2013) Norbert Jost et al.   JOURNAL OF PHYSIOLOGY-LONDON

Enhanced Sarcoplasmic Reticulum Ca 2+ Leak and Increased Na + -Ca 2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation

(2012) Niels Voigt et al.   CIRCULATION

Data-based theoretical identification of subcellular calcium compartments and estimation of calcium dynamics in cardiac myocytes

(2012) Leonid Livshitz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts

(2011) Norishige Morita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Profile of L-type Ca2+ current and Na+/Ca2+ exchange current during cardiac action potential in ventricular myocytes

(2011) Tamas Banyasz et al.   HEART RHYTHM

Alternative strategies in arrhythmia therapy: Evaluation of Na/Ca exchange as an anti-arrhythmic target

(2011) Gudrun Antoons et al.   PHARMACOLOGY & THERAPEUTICS

Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation

(2011) Thomas O'Hara et al.   PLoS Computational Biology

A novel computational model of the human ventricular action potential and Ca transient

(2009) Eleonora Grandi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pharmacological Inhibition of Na/Ca Exchange Results in Increased Cellular Ca 2+ Load Attributable to the Predominance of Forward Mode Block

(2008) Semir Ozdemir et al.   CIRCULATION RESEARCH