Association of Metabolites with Obesity and Type 2 Diabetes Based on FTO Genotype

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

(2014) Qibin Qi et al.   HUMAN MOLECULAR GENETICS

Relationship between the lipidome, inflammatory markers and insulin resistance

(2014) Martina Wallace et al.   Molecular BioSystems

Genomic and Metabolomic Profile Associated to Microalbuminuria

(2014) Vannina G. Marrachelli et al.   PLoS One

Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma

(2013) J. S. Ried et al.   ALLERGY

Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes

(2013) W. Xie et al.   DIABETES

Body shape analyses of large persons in South Korea

(2013) Woojin Park et al.   ERGONOMICS

Human metabolic correlates of body mass index

(2013) Steven C. Moore et al.   Metabolomics

Plasma Metabolomics Reveal Alterations of Sphingo- and Glycerophospholipid Levels in Non-Diabetic Carriers of the Transcription Factor 7-Like 2 Polymorphism rs7903146

(2013) Cornelia Then et al.   PLoS One

Metabolomics platforms for genome wide association studies—linking the genome to the metabolome

(2012) Jerzy Adamski et al.   CURRENT OPINION IN BIOTECHNOLOGY

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

(2012) A. Floegel et al.   DIABETES

Association of the common FTO-rs9939609 polymorphism with type 2 diabetes, independent of obesity-related traits in a Vietnamese population

(2012) Tran Quang Binh et al.   GENE

Genetic variation in metabolic phenotypes: study designs and applications

(2012) Karsten Suhre et al.   NATURE REVIEWS GENETICS

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

(2011) Yoon Shin Cho et al.   NATURE GENETICS

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth

(2010) Gaifen Liu et al.   BMC Medical Genetics

Meta-analysis Added Power to Identify Variants in FTO Associated With Type 2 Diabetes and Obesity in the Asian Population

(2010) Yun Liu et al.   Obesity

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Association between oxidized LDL, obesity and type 2 diabetes in a population-based cohort, the Health, Aging and Body Composition Study

(2009) Omer T. Njajou et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits

(2009) Yoon Shin Cho et al.   NATURE GENETICS

Fat Mass-and Obesity-Associated (FTO) Gene Variant Is Associated With Obesity: Longitudinal Analyses in Two Cohort Studies and Functional Test

(2008) L. Qi et al.   DIABETES

Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians

(2008) M. C.Y. Ng et al.   DIABETES

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS