Article
Oncology
Guixin Wang, Shuhao Zhang, Meiling Wang, Lin Liu, Yaqian Liu, Lianjun Tang, He Bai, Haidong Zhao
Summary: This meta-analysis found that occult metastases in axillary lymph nodes are associated with poorer prognosis in patients with breast cancer, with lower five-year and ten-year disease-free survival and overall survival rates.
Article
Multidisciplinary Sciences
Orlandric Miree, Sanjeev Kumar Srivastava, Mohammad Aslam Khan, Fnu Sameeta, Srijan Acharya, Harrison Ndetan, Karan Pal Singh, Kate Louise Hertweck, Santanu Dasgupta, Luciana Madeira da Silva, Rodney Paul Rocconi, James Elliot Carter, Seema Singh, Ajay Pratap Singh
Summary: The study found that aberrant MYB expression in ovarian cancer is positively correlated with tumor grades and stages, and has race-specific prognostic value for African American patients, but not for Caucasian American patients. High levels of MYB transcripts in epithelial ovarian cancer subtypes are associated with poor survival in African American patients, highlighting MYB as a potentially useful clinical biomarker for prognosis in this population.
SCIENTIFIC REPORTS
(2021)
Review
Surgery
M. G. Davey, E. J. Ryan, M. S. Davey, A. J. Lowery, N. Miller, M. J. Kerin
Summary: Studies have found that high PD-L1 expression in breast cancer is associated with aggressive clinical and pathological characteristics, and is more likely to achieve pathological complete response following treatment, but is also associated with lower overall survival rates.
BRITISH JOURNAL OF SURGERY
(2021)
Article
Oncology
Jingwei Du, Jun Feng, Deyan Luo, Lijuan Peng
Summary: The meta-analysis results suggest that COX-2 overexpression is significantly associated with increased risk, worse clinicopathological progression, and poorer prognosis of laryngeal cancer.
FRONTIERS IN ONCOLOGY
(2022)
Review
Oncology
Sheng Yang, Zongxin Zhang, Linglong Shen
Summary: The meta-analysis finds that increased C-reactive protein levels are significantly associated with poor overall survival and shortened progression-free survival in patients with cervical cancer.
FRONTIERS IN ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Wei Xu, Man Zhang, Lu Liu, Minyue Yin, Chunfang Xu, Zhen Weng
Summary: There is a correlation between mucins and their subtypes and the prognosis of patients with pancreatic cancer.
Article
Oncology
Katrin Almstedt, Anne-Sophie Heimes, Franziska Kappenberg, Marco J. Battista, Hans-Anton Lehr, Slavomir Krajnak, Antje Lebrecht, Mathias Gehrmann, Kathrin Stewen, Walburgis Brenner, Wolfgang Weikel, Joerg Rahnenfuehrer, Jan G. Hengstler, Annette Hasenburg, Marcus Schmidt
Summary: This study found that in breast cancer patients without lymph node metastasis, patients with HER2-low tumors had better prognosis compared to those with HER2-zero tumors. The HER2 status has independent prognostic significance for both disease-free survival and overall survival.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Oncology
Emma Zattarin, Daniele Presti, Luigi Mariani, Caterina Sposetti, Rita Leporati, Alice Menichetti, Chiara Corti, Chiara Benvenuti, Giovanni Fuca, Riccardo Lobefaro, Francesca Ligorio, Leonardo Provenzano, Andrea Vingiani, Marta Del Vecchio, Gaia Griguolo, Marianna Sirico, Ottavia Bernocchi, Antonio Marra, Paola Zagami, Elisa Agostinetto, Flavia Jacobs, Pierluigi Di Mauro, Andrea Esposito, Carlo Alberto Giorgi, Luca Lalli, Laura Boldrini, Pier Paolo Berton Giacchetti, Ambra Carnevale Schianca, Valentina Guarneri, Rebecca Pedersini, Agnese Losurdo, Alberto Zambelli, Daniele Generali, Carmen Criscitiello, Giuseppe Curigliano, Giancarlo Pruneri, Filippo de Braud, Maria Vittoria Dieci, Claudio Vernieri
Summary: In 428 patients with HR+/HER2- advanced breast cancer, HER2-low status was found to be independently associated with worse progression-free survival (PFS) and overall survival (OS) compared to HER2-0 status. These findings suggest that HER2-low status could serve as a new prognostic biomarker in this clinical setting.
Review
Oncology
Yifei Wang, Yaming Li, Jingshu Liang, Nan Zhang, Qifeng Yang
Summary: This meta-analysis aimed to summarize the clinical risk factors associated with the incidence of chemotherapy-induced amenorrhea (CIA) and evaluate their prognostic effects in breast cancer patients.
FRONTIERS IN ONCOLOGY
(2022)
Review
Oncology
Binyan Liu, Qi Peng, Ya-Wen Wang, Jianhao Qiu, Jiang Zhu, Rong Ma
Summary: Aberrant expression of FASN is associated with breast cancer development, but it does not have a significant impact on overall survival and relapse. However, FASN expression is correlated with tumor size and HER2 positivity.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Muthukrishnan Chandrika, Pei Jou Chua, Umamaheswari Muniasamy, Ruby Yun Ju Huang, Aye Aye Thike, Cheng Teng Ng, Puay Hoon Tan, George W. Yip, Boon Huat Bay
Summary: This study found that PHGDH plays a regulatory role in breast cancer cell proliferation, and its expression is associated with tumor severity and patient prognosis. It may serve as a potential prognostic marker and therapeutic target in breast cancer.
BREAST CANCER RESEARCH AND TREATMENT
(2021)
Article
Oncology
Elzbieta Zarychta, Barbara Ruszkowska-Ciastek, Kornel Bielawski, Piotr Rhone
Summary: This study examined the utility of SDF-1 alpha and selected vasculo-angiogenic parameters in predicting disease relapse in invasive breast cancer patients. The combination of SDF-1 alpha lower than 42 pg/dL and a number of circulating EPCs lower than 9.68 cells/μL showed strong diagnostic power for predicting disease relapse.
Article
Oncology
Binfeng Li, Fei Xiong, Shengzhong Yi, Sheng Wang
Summary: This study used a meta-analysis to comprehensively evaluate the prognostic and clinicopathologic significance of neutrophil-to-lymphocyte ratio (NLR) in patients with esophageal cancer. The results showed that elevated NLR was associated with poor prognosis and abnormal clinicopathologic parameters, including overall survival, cancer-specific survival, progression-free survival, and disease-free survival.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
(2022)
Article
Biochemistry & Molecular Biology
Vikrant Mehta, Jaipal Meena, Harit Kasana, Anjana Munshi, Harish Chander
Summary: The study found that CHAC1 is continuously up-regulated in breast cancer, associated with poor prognosis, and may be a promising candidate for breast cancer diagnosis and prognosis analysis.
MOLECULAR BIOLOGY REPORTS
(2022)
Article
Oncology
Huma Shehwana, Ayse G. Keskus, Sila E. Ozdemir, Azer A. Acikgoz, Rumeysa Biyik-Sit, Ilgin Cagnan, Damla Gunes, Ermira Jahja, Sahika Cingir-Koker, Gizem Olmezer, Ceren Sucularli, Ozlen Konu
Summary: The study found that CHRNA5 expression in breast cancer cells was induced by E2 in a dose- and time-dependent manner, with higher levels in ER- tumors than ER+ tumors. Higher CHRNA5 expression was associated with a worse prognosis in untreated breast cancer patients, as well as with secondary E2 signaling. The study uncoupled primary and secondary target genes, revealing distinct clustering patterns in multiple public datasets.
Article
Biotechnology & Applied Microbiology
Minggu Zhu, Qicai Wang, Zhaowen Luo, Kelong Liu, Zhiqiao Zhang
ONCOTARGETS AND THERAPY
(2018)
Article
Obstetrics & Gynecology
Dongmei Qiu, Wanqiu Cai, Zhiqiao Zhang, Hongyan Li, Dongmei Zhou
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2019)
Article
Oncology
Canchang Cheng, Qicai Wang, Minggu Zhu, Kelong Liu, Zhiqiao Zhang
CANCER CELL INTERNATIONAL
(2019)
Article
Oncology
Zhiqiao Zhang, Yanling Ouyang, Yiyan Huang, Peng Wang, Jing Li, Tingshan He, Qingbo Liu
CANCER CELL INTERNATIONAL
(2019)
Article
Oncology
Zhiqiao Zhang, Jing Li, Tingshan He, Yanling Ouyang, Yiyan Huang, Qingbo Liu, Peng Wang, Jianqiang Ding
Article
Oncology
Zhiqiao Zhang, Jing Li, Tingshan He, Yanling Ouyang, Yiyan Huang, Qingbo Liu, Peng Wang, Jianqiang Ding
CANCER CELL INTERNATIONAL
(2019)
Article
Medicine, Research & Experimental
Zhiqiao Zhang, Tingshan He, Liwen Huang, Yanling Ouyang, Jing Li, Yiyan Huang, Peng Wang, Jianqiang Ding
JOURNAL OF TRANSLATIONAL MEDICINE
(2019)
Article
Virology
Shubiao Lu, Jinsong Lin, Zhiqiao Zhang, Liping Xiao, Zhijian Jiang, Jia Chen, Chongjing Hu, Shi Luo
Summary: This study reported the screening, clinical features, and treatment process of a family cluster involving three COVID-19 patients. The discovery of the first asymptomatic carrier in this cluster relied on comprehensive epidemiological investigation and multiple detection methods, emphasizing the value of these approaches in detecting hidden asymptomatic carriers.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Medicine, Research & Experimental
Jieyi Liang, Tingshan He, Hong Li, Xueqing Guo, Zhiqiao Zhang
Summary: The current study aimed to develop a novel cancer artificial intelligence survival analysis system for predicting individual mortality risk curves for cervical carcinoma patients receiving different treatments. Three different artificial intelligence algorithms were used to develop prognostic models, and multiple independent influence factors were identified.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)