The Role of Hydrogen Sulfide in Evolution and the Evolution of Hydrogen Sulfide in Metabolism and Signaling

Ligand Field Theory and the Origin of Life as an Emergent Feature of the Periodic Table of Elements

(2016) Harold J. Morowitz et al.   BIOLOGICAL BULLETIN

Signaling Molecules: Hydrogen Sulfide and Polysulfide

(2015) Hideo Kimura   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide as an Oxygen Sensor

(2015) Kenneth R. Olson   ANTIOXIDANTS & REDOX SIGNALING

Signaling of Hydrogen Sulfide and Polysulfides

(2015) Hideo Kimura   ANTIOXIDANTS & REDOX SIGNALING

Anti-Inflammatory and Cytoprotective Actions of Hydrogen Sulfide: Translation to Therapeutics

(2015) John L. Wallace et al.   ANTIOXIDANTS & REDOX SIGNALING

Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems

(2015) Vivian S. Lin et al.   CHEMICAL SOCIETY REVIEWS

Persulfides: current knowledge and challenges in chemistry and chemical biology

(2015) Chung-Min Park et al.   Molecular BioSystems

Complex archaea that bridge the gap between prokaryotes and eukaryotes

(2015) Anja Spang et al.   NATURE

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

(2015) Tatiana V Mishanina et al.   Nature Chemical Biology

On the chemical biology of the nitrite/sulfide interaction

(2015) Miriam M. Cortese-Krott et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Kinetic and thermodynamic studies on the disulfide-bond reducing potential of hydrogen sulfide

(2015) Anita Vasas et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Neuroprotective effects of hydrogen sulfide and the underlying signaling pathways

(2015) Wen-Lin Chen et al.   REVIEWS IN THE NEUROSCIENCES

Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain

(2015) Yuka Kimura et al.   Scientific Reports

The Drive to Life on Wet and Icy Worlds

(2014) Michael J. Russell et al.   ASTROBIOLOGY

Biosynthesis of a Central Intermediate in Hydrogen Sulfide Metabolism by a Novel Human Sulfurtransferase and Its Yeast Ortholog

(2014) Scott L. Melideo et al.   BIOCHEMISTRY

Geological evidence of oxygenic photosynthesis and the biotic response to the 2400-2200 Ma “Great Oxidation Event”

(2014) J. William Schopf   BIOCHEMISTRY-MOSCOW

Interactions of hydrogen sulfide with myeloperoxidase

(2014) Zoltán Pálinkás et al.   BRITISH JOURNAL OF PHARMACOLOGY

Stable Sulfur and Oxygen Isotope Fractionation of Anoxic Sulfide Oxidation by Two Different Enzymatic Pathways

(2014) Alexander Poser et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: Implications of their possible biological activity and utility

(2014) Katsuhiko Ono et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sulfur and oxygen isotope insights into sulfur cycling in shallow-sea hydrothermal vents, Milos, Greece

(2014) William P Gilhooly et al.   GEOCHEMICAL TRANSACTIONS

Organization of the Human Mitochondrial Hydrogen Sulfide Oxidation Pathway

(2014) Marouane Libiad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in Biology

(2014) John Toohey et al.   MOLECULES

Hydrogen Sulfide and Polysulfides as Biological Mediators

(2014) Hideo Kimura   MOLECULES

The rise of oxygen in Earth’s early ocean and atmosphere

(2014) Timothy W. Lyons et al.   NATURE

Controversies and conundrums in hydrogen sulfide biology

(2014) Kenneth R. Olson et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro

(2014) Bartosz Szczesny et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Sphalerite is a geochemical catalyst for carbon-hydrogen bond activation

(2014) J. A. Shipp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

(2014) T. Ida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy at life's origin

(2014) W. F. Martin et al.   SCIENCE

Low Mid-Proterozoic atmospheric oxygen levels and the delayed rise of animals

(2014) N. J. Planavsky et al.   SCIENCE

Thiosulfate: a readily accessible source of hydrogen sulfide in oxygen sensing

(2013) Kenneth R. Olson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Polysulfides Link H2S to Protein Thiol Oxidation

(2013) Romy Greiner et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Signaling in the Gastrointestinal Tract

(2013) David R. Linden   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

(2013) Katalin Módis et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hydrogen sulfide is produced by cystathionine γ-lyase at the steady-state low intracellular Ca2+ concentrations

(2013) Yoshinori Mikami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of protein kinase A

(2013) Katalin Módis et al.   BIOCHEMICAL PHARMACOLOGY

On the antiquity of metalloenzymes and their substrates in bioenergetics

(2013) Wolfgang Nitschke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects

(2013) Katalin Módis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms

(2013) Csaba Szabo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Polysulfides are possible H2S-derived signaling molecules in rat brain

(2013) Yuka Kimura et al.   FASEB JOURNAL

Structure and Kinetic Analysis of H2S Production by Human Mercaptopyruvate Sulfurtransferase

(2013) Pramod Kumar Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atmospheric oxygenation three billion years ago

(2013) Sean A. Crowe et al.   NATURE

Chemical foundations of hydrogen sulfide biology

(2013) Qian Li et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Nutritional essentiality of sulfur in health and disease

(2013) Yves Ingenbleek et al.   NUTRITION REVIEWS

Beating the acetyl coenzyme A-pathway to the origin of life

(2013) W. Nitschke et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Early bioenergetic evolution

(2013) F. L. Sousa et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The inevitable journey to being

(2013) M. J. Russell et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Chlorosome antenna complexes from green photosynthetic bacteria

(2013) Gregory S. Orf et al.   PHOTOSYNTHESIS RESEARCH

Reactivity landscape of pyruvate under simulated hydrothermal vent conditions

(2013) Y. Novikov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen-sensitive mitochondrial accumulation of cystathionine  -synthase mediated by Lon protease

(2013) H. Teng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A theoretical examination of hydrogen sulfide metabolism and its potential in autocrine/paracrine oxygen sensing

(2013) Kenneth R. Olson   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Serpentinization, Carbon, and Deep Life

(2013) M. O. Schrenk et al.   Reviews in Mineralogy & Geochemistry

A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

(2013) Norihiro Shibuya et al.   Nature Communications

On the evolutionary ecology of symbioses between chemosynthetic bacteria and bivalves

(2012) Guus Roeselers et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Human Sulfide:Quinone Oxidoreductase Catalyzes the First Step in Hydrogen Sulfide Metabolism and Produces a Sulfane Sulfur Metabolite

(2012) Michael R. Jackson et al.   BIOCHEMISTRY

Turnstiles and bifurcators: The disequilibrium converting engines that put metabolism on the road

(2012) Elbert Branscomb et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics

(2012) Katalin Módis et al.   FASEB JOURNAL

Atmospheric oxygenation and volcanism

(2012) James F. Kasting et al.   NATURE

Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration

(2012) Motohiro Nishida et al.   Nature Chemical Biology

Peptide and RNA contributions to iron-sulphur chemical gardens as life's first inorganic compartments, catalysts, capacitors and condensers

(2012) S. E. McGlynn et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production

(2012) M. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TEMPERATURE AND CELL-TYPE DEPENDENCY OF SULFIDE EFFECTS ON MITOCHONDRIAL RESPIRATION

(2012) Michael Groeger et al.   SHOCK

Protein Domain Structure Uncovers the Origin of Aerobic Metabolism and the Rise of Planetary Oxygen

(2012) Kyung Mo Kim et al.   STRUCTURE

The Iron Biogeochemical Cycle Past and Present

(2012) Robert Raiswell et al.   Geochemical Perspectives

Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis

(2011) Kyle L. Flannigan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Sulfur signaling: Is the agent sulfide or sulfane?

(2011) John I. Toohey   ANALYTICAL BIOCHEMISTRY

Passive loss of hydrogen sulfide in biological experiments

(2011) Eric R. DeLeon et al.   ANALYTICAL BIOCHEMISTRY

Evolution of Photosynthesis

(2011) Martin F. Hohmann-Marriott et al.   Annual Review of Plant Biology

The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues

(2011) Omer Kabil et al.   ANTIOXIDANTS & REDOX SIGNALING

The reaction of H2S with oxidized thiols: Generation of persulfides and implications to H2S biology

(2011) Nestor E. Francoleon et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Prebiological Evolution and the Metabolic Origins of Life

(2011) Andrew J. Pratt   ARTIFICIAL LIFE

Iron-Sulfide-Bearing Chimneys as Potential Catalytic Energy Traps at Life's Emergence

(2011) Randall E. Mielke et al.   ASTROBIOLOGY

Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide

(2011) Yoshinori Mikami et al.   BIOCHEMICAL JOURNAL

Modulation of sulfide oxidation and toxicity in rat mitochondria by dehydroascorbic acid

(2011) Tatjana M. Hildebrandt   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Redox bifurcations: Mechanisms and importance to life now, and at its origin

(2011) Wolfgang Nitschke et al.   BIOESSAYS

Early evolution without a tree of life

(2011) William F Martin   Biology Direct

System xc- cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS

(2011) Richard J Bridges et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen, metals, bifurcating electrons, and proton gradients: The early evolution of biological energy conservation

(2011) William F. Martin   FEBS LETTERS

Hydrogen Sulfide Protects the Retina from Light-induced Degeneration by the Modulation of Ca2+Influx

(2011) Yoshinori Mikami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atmospheric oxygenation caused by a change in volcanic degassing pressure

(2011) Fabrice Gaillard et al.   NATURE

HIF-1 and SKN-1 Coordinate the Transcriptional Response to Hydrogen Sulfide in Caenorhabditis elegans

(2011) Dana L. Miller et al.   PLoS One

Primordial synthesis of amines and amino acids in a 1958 Miller H2S-rich spark discharge experiment

(2011) E. T. Parker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms and Evolution of Oxidative Sulfur Metabolism in Green Sulfur Bacteria

(2011) Lea H. Gregersen et al.   Frontiers in Microbiology

Mitochondria and Sulfide: A Very Old Story of Poisoning, Feeding, and Signaling?

(2010) Frédéric Bouillaud et al.   ANTIOXIDANTS & REDOX SIGNALING

Design, Fabrication, and Test of a Hydrothermal Reactor for Origin-of-Life Experiments

(2010) Randall E. Mielke et al.   ASTROBIOLOGY

Elucidating the Catalytic Mechanism of Sulfite Oxidizing Enzymes Using Structural, Spectroscopic, and Kinetic Analyses

(2010) Kayunta Johnson-Winters et al.   BIOCHEMISTRY

Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes

(2010) Emilie Lagoutte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Anaerobic animals from an ancient, anoxic ecological niche

(2010) Marek Mentel et al.   BMC BIOLOGY

Serpentinization as a source of energy at the origin of life

(2010) M. J. RUSSELL et al.   Geobiology

Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur

(2010) Martha H. Stipanuk et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Prebiotic Synthesis of Methionine and Other Sulfur-Containing Organic Compounds on the Primitive Earth: A Contemporary Reassessment Based on an Unpublished 1958 Stanley Miller Experiment

(2010) Eric T. Parker et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Inorganic sulfur oxidizing system in green sulfur bacteria

(2010) Hidehiro Sakurai et al.   PHOTOSYNTHESIS RESEARCH

Mosaic origin of the mitochondrial proteome

(2010) Radek Szklarczyk et al.   PROTEOMICS

The Hadean-Archaean Environment

(2010) N. H. Sleep   Cold Spring Harbor Perspectives in Biology

The Organic Composition of Carbonaceous Meteorites: The Evolutionary Story Ahead of Biochemistry

(2010) S. Pizzarello et al.   Cold Spring Harbor Perspectives in Biology

Mineral Surfaces, Geochemical Complexities, and the Origins of Life

(2010) R. M. Hazen et al.   Cold Spring Harbor Perspectives in Biology

Earth's Earliest Atmospheres

(2010) K. Zahnle et al.   Cold Spring Harbor Perspectives in Biology

Bioenergetics and Life's Origins

(2010) D. Deamer et al.   Cold Spring Harbor Perspectives in Biology

Inorganic Nitrogen Reduction and Stability under Simulated Hydrothermal Conditions

(2009) Jay A. Brandes et al.   ASTROBIOLOGY

Predation between prokaryotes and the origin of eukaryotes

(2009) Yaacov Davidov et al.   BIOESSAYS

The origins of phagocytosis and eukaryogenesis

(2009) Natalya Yutin et al.   Biology Direct

H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of Hyperhomocysteinemia

(2009) Taurai Chiku et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrothermal Focusing of Chemical and Chemiosmotic Energy, Supported by Delivery of Catalytic Fe, Ni, Mo/W, Co, S and Se, Forced Life to Emerge

(2009) Wolfgang Nitschke et al.   JOURNAL OF MOLECULAR EVOLUTION

No facilitator required for membrane transport of hydrogen sulfide

(2009) J. C. Mathai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new structure-based classification of sulfide:quinone oxidoreductases

(2009) Marco Marcia et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Evolution of the haem copper oxidases superfamily: a rooting tale

(2009) Simonetta Gribaldo et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels

(2008) M. H. Stipanuk et al.   AMINO ACIDS

Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria

(2008) Tatjana M. Hildebrandt et al.   FEBS Journal

Formation of Zn- and Fe-sulfides near hydrothermal vents at the Eastern Lau Spreading Center: implications for sulfide bioavailability to chemoautotrophs

(2008) Heileen Hsu-Kim et al.   GEOCHEMICAL TRANSACTIONS

The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

(2008) Chris E. Cooper et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Redox regulation of mitochondrial sulfide oxidation in the lugworm, Arenicola marina

(2008) T. M. Hildebrandt et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The Multiple Evolutionary Histories of Dioxygen Reductases: Implications for the Origin and Evolution of Aerobic Respiration

(2008) C. Brochier-Armanet et al.   MOLECULAR BIOLOGY AND EVOLUTION

The rise of atmospheric oxygen

(2008) Lee R. Kump   NATURE

The origin of the oxygen-evolving complex

(2007) J RAYMOND et al.   COORDINATION CHEMISTRY REVIEWS