Article
Chemistry, Physical
Kaviyarasan Raji, Senthil Kumar Thiyagarajan, Raghupathy Suresh, Ramanan Vadivel, Dharmalingam Palanivel, Perumal Ramamurthy
Summary: In this study, highly luminescent green C-dots were synthesized using neem seed kernel as the carbon precursor. These C-dots displayed good dispersion in water and showed high photostability. They were found to be harmless towards cells and were employed as a luminescent probe for multicolor cell imaging. The study also revealed a new method for detecting gold ions using the selective quenching of the C-dots' photoluminescence. Additionally, a simple and greener way to recover gold ions using the C-dots was explored.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Biochemistry & Molecular Biology
Elisabetta Esposito, Laura Calderan, Andrea Galvan, Enrica Cappellozza, Markus Drechsler, Paolo Mariani, Alessia Pepe, Maddalena Sguizzato, Enrico Vigato, Edoardo Dalla Pozza, Manuela Malatesta
Summary: This study investigated the transdermal fate of ethosomes and transethosomes on human skin. The results showed that the vesicle penetration capability was influenced by their physical-chemical features, with different vesicles reaching different levels of the skin. This offers potential for tailored transdermal drug delivery based on specific cutaneous pathologies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Pichayanun Sinthuprasert, Anuwut Petdum, Pattanawit Swanglap, Waraporn Panchan, Thanasat Sooksimuang, Nantanit Wanichacheva, Krit Setthakarn
Summary: A new highly productive quenching fluorescence sensor MDP was synthesized from a helicene anhydride derivative and propargyl bromide, showing significant photophysical properties and selectivity in distinguishing Au3+ ions. It has a detection limit of 0.16 mu mol L-1 or 32.0 ppb and can detect gold ions in real water samples, suggesting potential applications in biological and environmental systems.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2021)
Article
Food Science & Technology
Amal S. Albedwawi, Reem Al Sakkaf, Tareq M. Osaili, Ahmed Yusuf, Amin Olaimat, Shao-Quan Liu, Giovanni Palmisano, Nagendra P. Shah, Mutamed M. Ayyash
Summary: This paper investigated the ability of lactic acid bacteria (LAB) and Bifidobacterium to remove acrylamide (AA) and examined the mechanism(s) of the AA removal using various microscopic techniques. The results showed that Bifidobacterium breve and Lactiplantibacillus plantarum exhibited higher acrylamide reduction rates. The study also found that both strains could tolerate low pH levels and remove acrylamide under in vitro gastrointestinal conditions.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Junxiang Cai, Yiyun Wang, Daohuai Jiang, Songsong Zhang, Yuandong Alex Gu, Liang Lou, Fei Gao, Tao Wu
Summary: This paper describes the use of an aluminum nitride (AlN) piezoelectric micromachined ultrasound transducer (PMUT) array for high-resolution photoacoustic (PA) imaging. By utilizing the high-order resonance modes of the PMUT, the imaging resolution is improved. The PMUT, based on microelectromechanical systems (MEMS), is suitable for PA endoscopic imaging of blood vessels and bronchi due to its small size and high sensitivity. The study focuses on the characterization and analysis of the PMUT's high-order resonance modes, which provide higher frequencies and wider bandwidth for PA signal detection, leading to increased resolution compared to working at the fundamental resonance mode.
MICROSYSTEMS & NANOENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Francesca Ferrara, Mascia Benedusi, Franco Cervellati, Maddalena Sguizzato, Leda Montesi, Agnese Bondi, Markus Drechsler, Walter Pula, Giuseppe Valacchi, Elisabetta Esposito
Summary: In this study, transethosomes were explored as potential delivery systems for dimethyl fumarate. Formulative studies were conducted to investigate the effects of various compositions on the morphology and drug entrapment capacity of vesicles. Results showed that certain formulations were able to effectively improve wound healing and control drug release, indicating their potential application in wound treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Geology
Sebastian Fuchs, Dirk Schumann, Robert F. Martin, Martin Couillard
Summary: The high-grade gold mineralization in the Witwatersrand basin is closely related to carbonaceous nodules, veins, and seams, suggesting that hydrocarbons may have played a vital role in ore genesis. Through various scientific methods, it was found that gold, hydrocarbons, and associated mineral assemblages are closely related on a micro to nano scale, with hydrocarbons potentially acting as efficient chemical traps for the concentration of gold deposition and accumulation.
ORE GEOLOGY REVIEWS
(2021)
Article
Nanoscience & Nanotechnology
Xin-Meng Wang, Xing-Wang Wu, Xiao-Ying Zhao, Chen-Wei Wang, Jiang-Ning Zhou
Summary: The study evaluated different sized AuNPs injected into mice and identified three clear exposure-time-dependent patterns associated with AuNPs. Results showed no obvious differences in liver function, liver cell apoptosis, or autophagy upon exposure to AuNPs. Therefore, the study provides a framework for quickly obtaining informative trends about AuNP-triggered subcellular damage patterns.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2021)
Article
Multidisciplinary Sciences
Thomas Danz, Till Domroese, Claus Ropers
Summary: This research introduces ultrafast dark-field electron microscopy to investigate the order parameter across a structural phase transition, using ultrashort laser pulses to locally excite a thin film and imaging the transient state of the specimen with ultrashort electron pulses. The study tracks the evolution of charge-density wave domains in the material with femtosecond temporal and 5-nanometer spatial resolution, revealing relaxation pathways and domain wall dynamics. The selective contrast enhancement in this study will inspire future advancements in beam-shaping technology for ultrafast transmission electron microscopy.
Article
Materials Science, Multidisciplinary
Maowen Liu, Joerg Weissmueller
Summary: This study provides a direct observation of lattice defects in plastically deformed nanoporous gold, confirming the contribution of accumulation and interaction of defects to the strain hardening rate. The results show that plastic deformation significantly enhances the defect density, with twins formed on crystallographic planes and their interaction forming Lomer-Cottrell locks. This inhibits dislocation escaping, linking strain hardening to the accumulation and interaction of twins.
MATERIALS RESEARCH LETTERS
(2021)
Review
Chemistry, Multidisciplinary
Peter Tieu, Xingxu Yan, Mingjie Xu, Phillip Christopher, Xiaoqing Pan
Summary: The development of single atom catalysts (SACs) with carefully controlled properties has been driven by the need for atom efficient catalysts. Advances in transmission electron microscopy (TEM) techniques, including aberration correction, spectroscopy, and in situ/operando observation, have enabled researchers to study SACs at an atomic scale, providing crucial information about their location, characteristics, and stability.
Article
Automation & Control Systems
J. C. Cortes, A. Navarro-Quiles, F. J. Santonja, S. M. Sferle
Summary: This paper proposes a new approach by assuming that the parameters in both the PFO and PSO models are random variables, and solves both models probabilistically by obtaining the probability density functions of the corresponding solution processes. The theoretical findings are then applied to model the adsorption of cadmium ions onto tree fern using real data, and the results of the randomized PFO and PSO models are compared, with the PSO model being selected.
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
(2023)
Article
Chemistry, Physical
Markus Terker, Lars Nicolai, Samuel Gaucher, Jens Herfort, Achim Trampert
Summary: Isothermal crystallization of amorphous Ge on a cubic Fe3Si/GaAs(001) substrate results in the formation of epitaxially aligned tetragonal FeGe2 through a disorder-order phase transition involving rearrangement of the Fe/vacancy sublattice and reduction of the vertical lattice spacing across vacancy layers in the Ge sublattice for strain minimization. Crystallization and ordering proceed layer-by-layer with square-root-shaped kinetics, with a slower transition rate for ordering.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Materials Science, Multidisciplinary
Tae Gyu Yun, Yelyn Sim, Younghwan Lim, Dongho Kim, Ji-Sang An, Hyungdoh Lee, Yingge Du, Sung-Yoon Chung
Summary: This paper discusses the electrochemical electrolysis with aqueous electrolyte, focusing on the oxygen evolution reaction at the anode side. It identifies four significant origins affecting the stability of oxide-based OER catalysts and emphasizes the importance of research in this area.
Article
Chemistry, Multidisciplinary
Debaditya Chatterjee, Shuoyuan Huang, Kaichen Gu, Jianzhu Ju, Junguang Yu, Harald Bock, Lian Yu, M. D. Ediger, Paul M. Voyles
Summary: Physical vapor deposition is used to create stable organic glass systems with nanoscale orientational and translational ordering of molecules. Using low-dose 4D STEM and a 2 nm probe, we have mapped columnar order in glassy samples of a discotic mesogen. Both vapor-deposited and liquid-cooled glassy films show similar domains of orientation, with size variations depending on processing. These results demonstrate the potential of low-dose 4D STEM for characterizing mesoscale structures in molecular glass systems relevant to organic electronics.
Article
Chemistry, Applied
Kannan Badri Narayanan, Gyu Tae Park, Sung Soo Han
Summary: The development of graphene-polyiodide nanocomposites by utilizing soluble starch biopolymer as a functionalizing and reducing agent has shown to be effective in creating nanomaterials with superior antibacterial properties for food packaging applications. The nanocomposites exhibited good antibacterial activities against E. coli and S. aureus, showcasing potential as high-efficacy antibacterial starch-based nanomaterials.UV-visible spectroscopy, X-ray diffraction, Raman spectroscopy, scanning electron microscopy, and energy-dispersive spectroscopy were used to confirm the presence of polyiodide in the starch-reduced graphene oxide.
Article
Food Science & Technology
Kannan Badri Narayanan, Gyu Tae Park, Sung Soo Han
Summary: The study identified an antagonistic compound against multidrug-resistant Staphylococcus aureus strains from Pseudomonas aeruginosa YUSA1 isolated from freshwater. The crude ethyl acetate extract showed in vitro antibacterial and antibiofilm properties against MRSA, suggesting its potential use in food packaging materials with antibacterial effects.
Article
Chemistry, Physical
Priyanka Raju Thomball, Kummara Madhusudana Rao, Sunmi Zo, Kannan Badri Narayanan, Raju S. Thombal, Sung Soo Han
Summary: A highly efficient nitrogen-doped carbon sheet-like material (NCS) is developed via simple pyrolysis, which shows excellent catalytic activity towards the reduction of nitro-compounds and can be easily recovered and reused multiple times.
Article
Crystallography
Hyun Ho Park
Summary: IRG1 is an enzyme that is overexpressed during immune reactions and catalyzes the production of itaconate, which has antibacterial and antiviral activities. The exact mechanism of IRG1 enzymatic reaction remains unclear, but structural studies are expected to shed light on it.
Article
Chemistry, Multidisciplinary
Abdulrahman Ahmed Sharwani, Kannan Badri Narayanan, Mohammad Ehtisham Khan, Sung Soo Han
Summary: Silver-titania nanocomposites (Ag-TiO2 NCs) with excellent photocatalytic degradation properties and antibacterial activities were successfully synthesized. The green-synthesized NCs exhibited eco-friendly degradation of azo dye contaminants and showed good antibacterial activities against Staphylococcus aureus and Escherichia coli.
ARABIAN JOURNAL OF CHEMISTRY
(2021)
Review
Biotechnology & Applied Microbiology
Kannan Badri Narayanan, Sung Soo Han
Summary: The fabrication of novel biomaterial scaffolds with improved biological interactions and mechanical properties is crucial for tissue engineering. Protein/peptide-based polymeric scaffolds, especially those created through bioorthogonal enzymatic reactions, show great potential in replicating the in vivo microenvironment for cell differentiation and tissue formation. Peptide ligases, including natural ones like sortases and butelase 1, as well as engineered ones like trypsiligase and subtiligase, are efficient tools for enzymatic cross-linking of protein/peptide-based polymeric chains. These ligases can enhance cell attachment, growth, and differentiation by conjugating with cell-adhesive ECM proteins or motifs and growth factors. The review discusses the potential, limitations, and mechanisms of natural and engineered peptide ligases in the fabrication of (bio)polymeric scaffolds for various tissue engineering and regenerative applications.
ENZYME AND MICROBIAL TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Shaukat Khan, Mazhar Ul-Islam, Muhammad Wajid Ullah, Youlong Zhu, Kannan Badri Narayanan, Sung Soo Han, Joong Kon Park
Summary: This review summarizes the techniques used to develop 3D bacterial cellulose (BC) scaffolds and discusses their potential biomedical applications. It provides comprehensive coverage of the idea, requirements, synthetic strategies, and current and prospective applications of 3D BC scaffolds, making it useful for researchers working with polysaccharides, biopolymers, or composite materials.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Pharmacology & Pharmacy
Kummara Madhusudana Rao, Kannan Badri Narayanan, Uluvangada Thammaiah Uthappa, Pil-Hoon Park, Inho Choi, Sung Soo Han
Summary: In this study, multifunctional fungal mushroom-derived hydrogels were developed for wound dressing applications, with tissue adhesive, hemostasis, self-healing, and antibacterial properties. The hydrogels exhibited good swelling ratio, biodegradability, mechanical properties, and high adhesion strength to porcine skin. Additionally, they showed excellent antibacterial properties and promoted cell viability and attachment, making them a promising material for wound healing.
Article
Multidisciplinary Sciences
Abdulrahman Ahmed Sharwani, Kannan Badri Narayanan, Mohammad Ehtisham Khan, Sung Soo Han
Summary: This study successfully synthesized silver-loaded zinc oxide nanocomposites with unique morphologies and demonstrated their photocatalytic and antimicrobial abilities. These materials possess high thermal stability and large surface area, and show efficient degradation and bactericidal effects on various pollutants.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
Prakash Shrestha, Shiva Pathak, Shobha Regmi, Kannan Badri Narayanan, Tiep Tien Nguyen, Simmyung Yook, Jong Oh Kim, Jee-Heon Jeong
Summary: Extracellular matrix (ECM) is crucial for cell biology, and artificial microfibers mimicking ECM can enhance cell-polymeric fiber interactions and improve cell viability. Loading antioxidant drugs into microfibers further enhances cell viability.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Review
Pharmacology & Pharmacy
Kannan Badri Narayanan, Rakesh Bhaskar, Sung Soo Han
Summary: Nanogels (NGs), a significant nanoplatform with properties of both hydrogels and nanoparticles, have been extensively used for controlled/sustained delivery of therapeutic agents in biomedical and healthcare applications. This review summarizes the synthesis and functionalization strategies of NGs and highlights their recent advances in various biomedical fields such as cancer theranostics, immunotherapy, sensing, and tissue engineering.
Article
Materials Science, Multidisciplinary
Madeshwaran Sekkarapatti Ramasamy, Rakesh Bhaskar, Kannan Badri Narayanan, Shiv Dutt Purohit, Sang Shin Park, Amutheesan Manikkavel, Byungki Kim, Sung Soo Han
Summary: This study reports a method to fabricate nanofiber scaffolds with improved piezoelectric responses, surface properties, and cytocompatibility. The modified scaffolds showed enhanced mechanical properties and hydrophilicity compared to the original scaffolds, and had higher cell attachment and proliferation abilities. These scaffolds have potential applications in tissue growth and regeneration, medical detection, and biological force sensing.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Microbiology
Kannan Badri Narayanan, Rakesh Bhaskar, Yong Joo Seok, Sung Soo Han
Summary: The biological synthesis of nanocomposites provides a cost-effective and environmentally friendly way to produce materials with enhanced properties. In this study, zinc oxide and silver/zinc oxide nanocomposites were biosynthesized using the cell-free filtrate of Lysinibacillus sphaericus, and their properties were characterized using various techniques. The nanocomposites showed improved photocatalytic efficiency, cytotoxicity against cancer cells, and antibacterial activity, making them promising materials for biomedical and environmental applications.
Review
Neurosciences
Shampa Ghosh, Jitendra Kumar Sinha, Soumya Ghosh, Hitaishi Sharma, Rakesh Bhaskar, Kannan Badri Narayanan
Summary: This comprehensive review explores innovative therapies for epilepsy management, including responsive neurostimulation, vagus nerve stimulation, deep brain stimulation, gene therapies, and optogenetics. It also discusses adjunctive therapies like cannabidiol and the ketogenic diet. The importance of staying updated with emerging trends in epilepsy management is emphasized, along with the hope for improved therapeutic options.
Article
Polymer Science
Kannan Badri Narayanan, Rakesh Bhaskar, Kuncham Sudhakar, Dong Hyun Nam, Sung Soo Han
Summary: In this study, BC hydrogel was functionalized with PDA and used in skin tissue engineering. Characterization techniques were used to investigate the formation of PDA on BC nanofibers. The BC/PDA hydrogels showed excellent tensile strength, water-wetting ability, and enhanced cell viability, making them potential biocompatible alternatives for skin tissue engineering and wound-dressing applications.