A systems biology approach to investigate the mechanism of action of trabectedin in a model of myelomonocytic leukemia

Targeting the EWS–FLI1 transcription factor in Ewing sarcoma

(2015) R. Tancredi et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Molecular Precision Chemotherapy: Overcoming Resistance to Targeted Therapies?

(2014) Stefan Burdach   CLINICAL CANCER RESEARCH

Wiring miRNAs to pathways: a topological approach to integrate miRNA and mRNA expression profiles

(2014) Enrica Calura et al.   NUCLEIC ACIDS RESEARCH

Thioridazine, an antipsychotic drug, elicits potent antitumor effects in gastric cancer

(2014) JIASHENG MU et al.   ONCOLOGY REPORTS

Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L)

(2014) K-j Min et al.   Cell Death & Disease

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

(2013) Giovanni Germano et al.   CANCER CELL

Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth

(2013) Patrick J. Grohar et al.   CLINICAL CANCER RESEARCH

Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

(2012) Eleftherios Sachlos et al.   CELL

Resveratrol in human cancer chemoprevention - Choosing the ‘right’ dose

(2011) Edwina Scott et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells

(2010) G. Germano et al.   CANCER RESEARCH

A Review of Trabectedin (ET-743): A Unique Mechanism of Action

(2010) Maurizio D'Incalci et al.   MOLECULAR CANCER THERAPEUTICS

Irinotecan pharmacogenomics

(2010) Sharon Marsh et al.   PHARMACOGENOMICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

A census of human transcription factors: function, expression and evolution

(2009) Juan M. Vaquerizas et al.   NATURE REVIEWS GENETICS

PID: the Pathway Interaction Database

(2008) Carl F. Schaefer et al.   NUCLEIC ACIDS RESEARCH