A pure chloride channel mutant of CLC-5 causes Dent’s disease via insufficient V-ATPase activation

Preserved Na/HCO3 cotransporter sensitivity to insulin may promote hypertension in metabolic syndrome

(2015) Motonobu Nakamura et al.   KIDNEY INTERNATIONAL

V-ATPase/mTOR Signaling Regulates Megalin-Mediated Apical Endocytosis

(2014) Eva Maria Gleixner et al.   Cell Reports

Conformational defects underlie proteasomal degradation of Dent's disease-causing mutants of ClC-5

(2013) Christina D’Antonio et al.   BIOCHEMICAL JOURNAL

A model of lysosomal pH regulation

(2013) Yoichi Ishida et al.   JOURNAL OF GENERAL PHYSIOLOGY

Japanese Dent disease has a wider clinical spectrum than Dent disease in Europe/USA: genetic and clinical studies of 86 unrelated patients with low-molecular-weight proteinuria

(2013) Takashi Sekine et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Slc26a11 is prominently expressed in the brain and functions as a chloride channel: expression in Purkinje cells and stimulation of V H+-ATPase

(2013) Negah Rahmati et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Identification of dominant negative effect of L522P mutation in the electrogenic Na+–HCO3 − cotransporter NBCe1

(2013) Osamu Yamazaki et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Chloride in Vesicular Trafficking and Function

(2012) Tobias Stauber et al.   Annual Review of Physiology

On the Mechanism of Gating Charge Movement of ClC-5, a Human Cl−/H+ Antiporter

(2012) Giovanni Zifarelli et al.   BIOPHYSICAL JOURNAL

ClC-5 mutations associated with Dent’s disease: a major role of the dimer interface

(2011) Stéphane Lourdel et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Functional characterization of nonsynonymous single nucleotide polymorphisms in the electrogenic Na+–HCO 3 − cotransporter NBCe1A

(2011) Osamu Yamazaki et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Role of CFTR and ClC-5 in Modulating Vacuolar H+-ATPase Activity in Kidney Proximal Tubule

(2010) Luciene R. Carraro-Lacroix et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Proton block of the CLC-5 Cl−/H+exchanger

(2010) Alessandra Picollo et al.   JOURNAL OF GENERAL PHYSIOLOGY

Direct endosomal acidification by the outwardly rectifying CLC-5 Cl−/H+exchanger

(2010) Andrew J. Smith et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dent's disease

(2010) Olivier Devuyst et al.   Orphanet Journal of Rare Diseases

Dent’s disease: clinical features and molecular basis

(2010) Félix Claverie-Martín et al.   PEDIATRIC NEPHROLOGY

Lysosomal Pathology and Osteopetrosis upon Loss of H+-Driven Lysosomal Cl- Accumulation

(2010) S. Weinert et al.   SCIENCE

Endosomal Chloride-Proton Exchange Rather Than Chloride Conductance Is Crucial for Renal Endocytosis

(2010) G. Novarino et al.   SCIENCE

HIF-Prolyl Hydroxylases in the Rat Kidney

(2009) Johannes Schödel et al.   AMERICAN JOURNAL OF PATHOLOGY

Conversion of the 2 Cl−/1 H+ antiporter ClC-5 in a NO3−/H+ antiporter by a single point mutation

(2009) Giovanni Zifarelli et al.   EMBO JOURNAL

Novel CLCN5 mutations in patients with Dent’s disease result in altered ion currents or impaired exchanger processing

(2009) Teddy Grand et al.   KIDNEY INTERNATIONAL