N-Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

(2015) Sudeshna Roy et al.   ChemMedChem

The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

(2015) Paolo Bernardi et al.   PHYSIOLOGICAL REVIEWS

NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models

(2014) A. Zulian et al.   HUMAN MOLECULAR GENETICS

F-ATPase ofDrosophila melanogasterForms 53-Picosiemen (53-pS) Channels Responsible for Mitochondrial Ca2+-induced Ca2+Release

(2014) Sophia von Stockum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition

(2014) Michela Carraro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cinnamic Anilides as New Mitochondrial Permeability Transition Pore Inhibitors Endowed with Ischemia-Reperfusion Injury Protective Effect in Vivo

(2014) Daniele Fancelli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dimers of mitochondrial ATP synthase form the permeability transition pore

(2013) V. Giorgio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mitochondrial permeability transition from yeast to mammals

(2010) Luca Azzolin et al.   FEBS LETTERS

Regulation of the Inner Membrane Mitochondrial Permeability Transition by the Outer Membrane Translocator Protein (Peripheral Benzodiazepine Receptor)

(2010) Justina Šileikytė et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice

(2010) Erin R. Wissing et al.   NEUROMUSCULAR DISORDERS

The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects inCol6a1−/−myopathic mice

(2009) T Tiepolo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

(2008) Douglas P Millay et al.   NATURE MEDICINE

Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies

(2008) Luciano Merlini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA