Article
Clinical Neurology
Victoria A. Grunberg, Ryan A. Mace, Sarah M. Bannon, Jonathan Greenberg, Jafar Bakhshaie, Ana-Maria Vranceanu
Summary: The study suggests that pain catastrophizing and mindfulness are important intervention targets to enhance emotional functioning for chronic pain patients, and should be considered simultaneously in interventions.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Yuanyuan Chen, Peijun Ju, Qingrong Xia, Peng Cheng, Jianliang Gao, Loufeng Zhang, Hua Gao, Xialong Cheng, Tao Yu, Junwei Yan, Qiru Wang, Cuizhen Zhu, Xulai Zhang
Summary: This study aimed to investigate the association between pain catastrophizing and comorbidity of major depressive disorder (MDD) and chronic pain (CP). The results showed that pain catastrophizing and anxiety were more severe in the comorbidity group compared to the MDD-only group and healthy control group. Pain catastrophizing and anxiety may potentially impact the comorbidity of depression and chronic pain.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Anesthesiology
Hannah Durand, Katie Monahan, Brian E. McGuire
Summary: This study investigated the prevalence and impact of primary dysmenorrhea among third-level students in Ireland, revealing a high prevalence rate of 91.5%. Nonpharmacological pain management strategies were found to be popular, and pain catastrophizing was identified as a significant predictor of pain intensity and interference with daily activities.
Article
Anesthesiology
Srdjan S. Nedeljkovic, Inkyung Song, Xiaodong Bao, Jose L. Zeballos, Darin J. Correll, Yi Zhang, Johanna S. Ledley, Ashish Bhandari, Xiang Bai, Sang Rim Lee, Sunyoung Cho
Summary: This study investigated the efficacy and safety of VVZ-149 as an analgesic for postoperative pain after colorectal surgery. The results showed that VVZ-149 may benefit patients with negative affect and higher postoperative opioid use, but did not significantly reduce pain intensity.
JOURNAL OF CLINICAL ANESTHESIA
(2022)
Article
Medicine, General & Internal
Monica Magarinos Lopez, Maria Jose Lobato Rodriguez, Angela Menendez Garcia, Sophie Garcia-Cid, Ana Royuela, Augusto Pereira
Summary: The study found that women with CPP have high levels of neuroticism, low extraversion, and low conscientiousness, along with moderate to severe levels of depression, high levels of trait and state anxiety, catastrophizing, and low pain acceptance. These psychological factors are important to consider in developing interventions to improve the clinical course of CPP.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Yair Sharav, Yaron Haviv, Rafael Benoliel
Summary: The purpose of this study is to explore the potential differences between orofacial migraine (OFM) and neurovascular orofacial pain (NVOP). Facial presentations of primary headache resemble primary headache disorders, but they occur in specific locations associated with the trigeminal nerve. The International Classification of Orofacial Pain, 1st edition (ICOP) classifies these conditions as orofacial pains resembling primary headaches, including OFM and NVOP. The subtle differences and similar response to therapy suggest a possible overlap between NVOP and OFM, and further investigations are needed to separate them into distinct entities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Orthopedics
Juhong Pei, Haixia Chen, Tong Ma, Ying Zhang, Xiangfu Wang, Chenxu Li, Binglin Ye, Xingsheng Wang, Jirong Zhao, Xinman Dou
Summary: This study investigated the current state and associated factors of preoperative pain catastrophizing in patients undergoing total knee arthroplasty. The results showed that anxiety was the most relevant factor for pain catastrophizing, and lower education levels, poor physical function, and stronger pain intensity during activity were also associated with pain catastrophizing.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Clinical Neurology
Rachel Aaron, Lakeya S. McGill, Patrick H. Finan, Stephen T. Wegener, Claudia M. Campbell, Chung Jung Mun
Summary: Difficulties with pain-specific and general emotion regulation have negative impacts on pain outcomes. A study on adults with chronic pain identified four groups with different emotion regulation profiles and found that those with pain-specific and general ER difficulties had the worst outcomes. The findings highlight the importance of individualizing pain psychology treatment based on emotion regulation strengths and difficulties.
Article
Clinical Neurology
Gilad J. Regev, Roi Treister, Silviu Brill, Dror Ofir, Khalil Salame, Zvi Lidar, Morsi Khashan, Rivka Litvin, Uri Hochberg
Summary: The study aimed to assess patients' perceptions, misconceptions, and experience of anxiety-related symptoms following direct access to their thoraco-lumbar spine radiology report. Results showed that 63% of patients found reading the report helpful in understanding their condition, and 84% agreed that early access to the report improved communication with their physician. However, direct access to radiology reports may provoke anxiety symptoms, especially in patients with a tendency for catastrophic thinking.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Psychology, Clinical
Heba Khalil, Abedalmajeed Shajrawi, Ghadeer Dweik, Abeer Zaghmouri, Richard Henker
Summary: The study found that preoperative pain catastrophizing and anxiety symptoms can predict the severity of postoperative pain, while preoperative depressive and stress symptoms are not significantly associated with postoperative pain.
JOURNAL OF HEALTH PSYCHOLOGY
(2021)
Article
Clinical Neurology
Rachel L. Cundiff-O'Sullivan, Yang Wang, Sharon Thomas, Shijun Zhu, Claudia M. Campbell, Luana Colloca
Summary: This study utilized structural equation modeling to analyze the impact of psychological and sociodemographic factors on pain severity, interference, and jaw limitation in temporomandibular disorder (TMD) patients, and found that the dimensions of pain catastrophizing do not mediate these relationships.
Article
Orthopedics
Thomas J. Wood, Aaron M. Gazendam, Conrad B. Kabali
Summary: The study found that TJA patients with anxiety, depression, or pain catastrophizing have worse pain and function outcomes preoperatively and postoperatively. However, clinically significant improvement can be expected following hip/knee arthroplasty compared to preoperative status.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Psychology, Multidisciplinary
Pierluigi Diotaiuti, Stefano Corrado, Stefania Mancone, Elisa Cavicchiolo, Andrea Chirico, Thais Cristina Siqueira, Alexandro Andrade
Summary: This study aimed to validate a short model of the FPQ-III for the Italian context. The results confirmed the three-factor structure of the questionnaire and provided evidence of its good predictive validity and discriminant assessment.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Anesthesiology
Alicia E. Lopez-Martinez, Carmen Ramirez-Maestre, Elena R. Serrano-Ibanez, Gema T. Ruiz-Parraga, Rosa Esteve
Summary: This study is the first to explore the interrelationship between intolerance of uncertainty, catastrophizing, and anxiety in relation to perceived pain intensity. The findings support intolerance of uncertainty as a relevant psychological variable that is distinct from other relevant constructs in the setting of pain research and treatment.
Article
Neurosciences
Glauce Crivelaro Nascimento, Guilherme Lucas, Christie Ramos Andrade Leite-Panissi
Summary: Despite being some of the most commonly reported risk factors, the neural basis underlying the aggregation of emotional disorders in orofacial pain has been poorly studied. In this study, using a rat model of persistent orofacial pain induced by complete Freund's adjuvant (CFA) injection, we investigated the plasticity of astrocytes and microglia in key brain regions involved in the affective component of pain. Our results showed that CFA-induced temporomandibular inflammation caused changes in GFAP and Iba-1 expression in specific regions related to emotional behavior, and this change was time-dependent. Furthermore, we observed a positive correlation between upregulation of GFAP and Iba-1 and increased mechanical hypersensitivity. These findings suggest an important role for glial cells in the affective-motivational dimension of orofacial pain.
BRAIN RESEARCH BULLETIN
(2023)
Article
Rehabilitation
Marc Terradas-Monllor, Mirari Ochandorena-Acha, Hector Beltran-Alacreu, Ester Garcia Oltra, Fernando Collado Saenz, Jose Hernandez Hermoso
Summary: This study evaluated the feasibility and clinical impact of a home-based multimodal physiotherapy intervention in reducing pain catastrophizing and pain before total knee arthroplasty. The results showed that this treatment method has significant effects in reducing pain and pain catastrophizing.
PHYSIOTHERAPY THEORY AND PRACTICE
(2023)
Review
Anesthesiology
Leonardo Rodriguez Lagos, Alberto Arribas-Romano, Josue Fernandez-Carnero, Yeray Gonzalez-Zamorano, Sofia Laguarta Val
Summary: This study conducted a systematic review and meta-analysis to investigate the effects of percutaneous electrical nerve stimulation (PENS) and transcutaneous electrical nerve stimulation (TENS) on endogenous pain mechanisms in patients with musculoskeletal pain. The results showed that PENS and TENS have a mild to moderate immediate effect on local mechanical hypersensitivity, but this effect is not sustained over time. Further studies are needed to determine the effects on central pain mechanisms.
Article
Anesthesiology
Eva Huysmans, Lisa Goudman, Wouter Van Bogaert, Jo Nijs, Koen Putman, Maarten Moens, Ronald Buyl, Kelly Ickmans, Guillermo Garcia Barajas, Josue Fernandez-Carnero, Iris Coppieters
Summary: This cross-sectional study aimed to investigate the associations between pain intensity, cognitions, and quantitative sensory testing in patients scheduled for surgery for lumbar radiculopathy. The study found evidence of impaired inhibitory response to nociceptive stimuli and maladaptive pain cognitions in this population. However, there were no significant relationships between electrical detection thresholds and pain cognitions or pain intensity in these patients.
Letter
Orthopedics
Ferran Cuenca-Martinez, Roy La Touche, Clovis Varangot-Reille, Maeva Sardinoux, Jade Bahier, Luis Suso-Marti, Josue Fernandez-Carnero
Article
Chemistry, Multidisciplinary
Victor Riquelme-Aguado, Antonio Gil-Crujera, Josue Fernandez-Carnero, Ferran Cuenca-Martinez, Guillermo Baviano Klett, Francisco Gomez Esquer
Summary: The aim of this study was to evaluate whether emotional and cognitive factors influence the limb laterality discrimination task in women with fibromyalgia syndrome (FMS). The results showed that FMS patients had longer reaction times for laterality discrimination in hands and exhibited emotional and cognitive disorders compared with healthy subjects. However, there was no correlation between limb laterality discrimination and psychological variables.
APPLIED SCIENCES-BASEL
(2023)
Review
Biology
Silvia Di-Bonaventura, Josue Fernandez-Carnero, Luis Matesanz-Garcia, Alberto Arribas-Romano, Andrea Polli, Raul Ferrer-Pena
Summary: The main objective of this review was to examine the impact of different physiotherapy interventions on BDNF levels and analyze their effects on pain levels. The results showed that rTMS and EIMS interventions were more effective in reducing pain intensity and increasing BDNF levels compared to other physical therapies in chronic myofascial pain patients.
Article
Biology
Josue Fernandez-Carnero, Hector Beltran-Alacreu, Alberto Arribas-Romano, Ester Cerezo-Tellez, Juan Nicolas Cuenca-Zaldivar, Eleuterio A. Sanchez-Romero, Sergio Lerma Lara, Jorge Hugo Villafane
Summary: This study aims to develop a predictive learning approach to determine the prognostic value of basal outcomes for Mulligan's mobilization technique in chronic neck pain patients. The analysis of a dataset of 80 participants revealed that higher levels of anxiety and lower range of motion in lateroflexion were the most important predictive factors for successful recovery with the Mulligan concept treatment.
Article
Biology
Marta Carlota Diaz-Saez, Hector Beltran-Alacreu, Javier Gil-Castillo, Alfonso Gil-Martinez
Summary: This study compared the maximum tongue force between females with chronic temporomandibular disorders and asymptomatic females, and investigated the relationship between pain and fatigue and maximum tongue force. The results showed significant differences in maximum tongue force between the two groups, except for lip pressure measurement. Additionally, there were significant differences in perceived orofacial fatigue intensity between the groups. However, there were no significant correlations between perceived orofacial pain and fatigue and maximum tongue force.
Review
Sport Sciences
Gonzalo Navarro-Fernandez, Alfonso Gil-Martinez, Marta Carlota Diaz-Saez, Ignacio Elizagaray-Garcia, Paloma Qinling Pili-Mayayo, Julian Esteban Ocampo-Vargas, Hector Beltran-Alacreu
Summary: This systematic review aimed to evaluate the effectiveness of physiotherapy interventions in the rehabilitation of patients after orthognathic surgery (OS). The results showed limited effects of physiotherapy interventions on variables such as range of motion, pain, edema, and masticatory muscle strength. However, laser therapy and LED showed moderate evidence in postoperative neurosensory rehabilitation of the inferior alveolar nerve compared to a placebo LED intervention.
JOURNAL OF FUNCTIONAL MORPHOLOGY AND KINESIOLOGY
(2023)
Review
Rehabilitation
Oliver Martinez-Pozas, Eleuterio A. Sanchez-Romero, Hector Beltran-Alacreu, Alberto Arribas-Romano, Ferran Cuenca-Martinez, Jorge Hugo Villafane, Josue Fernandez-Carnero
Summary: This umbrella review with meta-meta-analysis found that orthopedic manual therapy had a small-moderate effect on mechanical hyperalgesia, with moderate-quality evidence and no heterogeneity. It also had a small effect on temporal summation, with moderate heterogeneity and low-quality evidence. Additionally, orthopedic manual therapy improved conditioned pain modulation with low-quality evidence. However, its effects were limited to immediate and short-term.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Review
Clinical Neurology
Diego Serrano-Munoz, Hector Beltran-Alacreu, David Martin-Caro Alvarez, Juan Jose Fernandez-Perez, Javier Aceituno-Gomez, Ruben Arroyo-Fernandez, Juan Avendano-Coy
Summary: This systematic review and meta-analysis aimed to determine the effectiveness of different electrical stimulation modalities in patients with temporomandibular disorders. The results showed that transcutaneous electrical nerve stimulation (TENS) and high-voltage current stimulation can significantly reduce musculoskeletal pain, but have no significant effect on range of movement and muscle activity.
Article
Medicine, General & Internal
Alberto Arribas-Romano, Josue Fernandez-Carnero, Yeray Gonzalez-Zamorano, Leonardo Rodriguez-Lagos, Isabel Maria Alguacil-Diego, Miguel Molina-Alvarez, David Morales Tejera, Francisco Mercado-Romero
Summary: The aim of this study was to investigate the mechanisms through which manual therapy (MT) works in patients with neck pain, comparing the effects of painful and pain-free MT treatment. The results showed that the immediate and short-term effects of MT on neck pain are not mediated by mechanisms related to conditioned pain modulation (CPM).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biology
Marta Carlota Diaz-Saez, Alfonso Gil-Martinez, Inae Caroline Gadotti, Gonzalo Navarro-Fernandez, Javier Gil-Castillo, Hector Beltran-Alacreu
Summary: A new low-cost device was developed to evaluate tongue force in an asymptomatic population. The device showed good-to-excellent intra- and inter-reliability and good responsiveness. It could be a new, more accessible tool for assessing and treating different clinical conditions involving a deficit in tongue force.
Article
Anesthesiology
Alberto Arribas-Romano, Josue Fernandez-Carnero, Yeray Gonzalez-Zamorano, Leonardo Rodriguez-Lagos, Francisco Gurdiel-Alvarez, Miguel Molina-Alvarez, David Morales Tejera, Francisco Mercado
Summary: The study revealed that young adult students with chronic or recurrent non-specific neck pain exhibit remote hyperalgesia and symptoms of depression and anxiety, but do not have dysfunctional conditioned pain modulation.
Review
Neurosciences
Ferran Cuenca-Martinez, Nuria Sempere-Rubio, Sara Molla-Casanova, Elena Munoz-Gomez, Josue Fernandez-Carnero, Alberto Sanchez-Sabater, Luis Suso-Marti
Summary: This study aimed to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) in patients with fibromyalgia (FMS). Eleven systematic reviews were included in the analysis. The results showed that high-frequency rTMS significantly reduced pain intensity at a 1-month follow-up, while the effects of low-frequency rTMS were uncertain. There was a significant effect on pain intensity up to 1-week post-intervention for the combination of high and low-frequency rTMS, but the results were controversial in the follow-up. rTMS was effective in improving general health but not in managing depressive symptoms and anxiety.
