The Role of Metformin in Controlling Oxidative Stress in Muscle of Diabetic Rats

Kinase-SUMO networks in diabetes-mediated cardiovascular disease

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Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling

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Association between systemic oxidative stress and insulin resistance/sensitivity indices - the PREDIAS study

(2015) Steffi Kopprasch et al.   CLINICAL ENDOCRINOLOGY

Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes

(2015) Ingrid M. Libman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages

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Assessment of anti-diabetic activity of an ethnopharmacological plant Nerium oleander through alloxan induced diabetes in mice

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Insulin resistance in type 1 diabetes mellitus

(2015) Kirti Kaul et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Vascular function in health, hypertension, and diabetes: effect of physical activity on skeletal muscle microcirculation

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Coping with oxidative stress

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A Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Metformin Therapy in Overweight/Obese Youth with Type 1 Diabetes

(2015) Benjamin Udoka Nwosu et al.   PLoS One

Myosin Va mediates Rab8A-regulated GLUT4 vesicle exocytosis in insulin-stimulated muscle cells

(2014) Yi Sun et al.   MOLECULAR BIOLOGY OF THE CELL

Architecture of mammalian respiratory complex I

(2014) Kutti R. Vinothkumar et al.   NATURE

Metformin Impairs Mitochondrial Function in Skeletal Muscle of Both Lean and Diabetic Rats in a Dose-Dependent Manner

(2014) Bart Wessels et al.   PLoS One

Lack of metformin effect on mouse embryo AMPK activity: implications for metformin treatment during pregnancy

(2013) Hyung-yul Lee et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Increase in Total Antioxidant Capacity of Plasma despite High Levels of Oxidative Stress in Uncomplicated Type 2 Diabetes Mellitus

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Metformin Reduces Endogenous Reactive Oxygen Species and Associated DNA Damage

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The Lipid Peroxidation By-Product 4-Hydroxy-2-Nonenal (4-HNE) Induces Insulin Resistance in Skeletal Muscle through Both Carbonyl and Oxidative Stress

(2012) Nicolas J. Pillon et al.   ENDOCRINOLOGY

Increasing Glucose 6-Phosphate Dehydrogenase Activity Restores Redox Balance in Vascular Endothelial Cells Exposed to High Glucose

(2012) Zhaoyun Zhang et al.   PLoS One

Mammalian NADH:ubiquinone oxidoreductase (Complex I) and nicotinamide nucleotide transhydrogenase (Nnt) together regulate the mitochondrial production of H2O2—Implications for their role in disease, especially cancer

(2011) Simon P. J. Albracht et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Intensive insulin treatment induces insulin resistance in diabetic rats by impairing glucose metabolism-related mechanisms in muscle and liver

(2011) Maristela Mitiko Okamoto et al.   JOURNAL OF ENDOCRINOLOGY

Metformin induces suppression of NAD(P)H oxidase activity in podocytes

(2010) Agnieszka Piwkowska et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An energetic tale of AMPK-independent effects of metformin

(2010) Russell A. Miller et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxidative stress and metabolic syndrome

(2009) Christian K. Roberts et al.   LIFE SCIENCES

Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes

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