Article
Multidisciplinary Sciences
Alejandro Prats Lujan, Mohammad Faizan Bhat, Sona Tsaturyan, Ronald van Merkerk, Haigen Fu, Gerrit J. Poelarends
Summary: The selective enzymatic reduction of nitroaliphatic and nitroaromatic compounds is challenging. In this study, the authors demonstrate the light-powered, selective photoenzymatic synthesis of aliphatic amines and amino-, azoxy- and azo-aromatics using flavin-dependent nitroreductases and chlorophyll as photocatalyst.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Menghui Song, Hongyan Zhou, Ganggang Wang, Ben Ma, Yajing Jiang, Jingya Yang, Congde Huo, Xi-Cun Wang
Summary: A new visible-light-promoted transfer hydrogenation of azobenzenes has been developed, with the reactions proceeding smoothly in methanol at ambient temperature in the presence of B(2)pin(2). Azobenzenes with diverse functional groups were reduced to hydrazobenzenes with a high yield of up to 96%. Preliminary mechanistic studies suggest that the hydrogen atom comes from the solvent and the transformation occurs via a radical pathway.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Domna Iordanidou, Michael G. Kallitsakis, Marina A. Tzani, Dimitris I. Ioannou, Tryfon Zarganes-Tzitzikas, Constantinos G. Neochoritis, Alexander Domling, Michael A. Terzidis, Ioannis N. Lykakis
Summary: This study reported the synthesis of 3,4-dihydroquinoxalin-2-ones through the selective reduction reaction catalyzed by supported gold nanoparticles. The reaction proceeded through heterogeneous transfer hydrogenation and intramolecular C-N transamidation, resulting in good functional-group tolerance and high yields.
Article
Chemistry, Analytical
Shamsunnahar Suchana, Langping Wu, Elodie Passeport
Summary: Compound-specific isotope analysis (CSIA) is a useful tool for studying the fate of legacy groundwater contaminants, but its application to nonconventional contaminants is still emerging. This study validated CSIA methods for nitro- and amino-substituted chlorobenzenes and developed a solid-phase extraction (SPE) method to minimize matrix interferences. The results showed that the SPE-CSIA procedure had negligible isotope fractionation and can be used to track the environmental fate of these contaminants.
ANALYTICAL CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Fuad Othman Abdullah, Leila Behrouzi, Babak Kaboudin
Summary: This study developed a method for synthesizing highly stable PdNPs on AO extract, demonstrating its efficient catalytic activity in the reduction of nitroaromatic compounds. Characterization of the catalyst and investigation of product yields confirmed its practicality and high efficiency in the reaction.
MATERIALS RESEARCH EXPRESS
(2021)
Article
Chemistry, Physical
Binbin Feng, Rou Guo, Qiulan Cai, Yaping Song, Nan Li, Yanghe Fu, De-Li Chen, Jiangwei Zhang, Weidong Zhu, Fumin Zhang
Summary: This study provides an approach for fabricating isolated nickel single-atom sites catalyst with high performance in catalytic transfer hydrogenation reaction for aniline synthesis. The hollow structure facilitates the enhancement of catalytic performance.
Article
Chemistry, Organic
Shashi Kumar, Sushil K. Maurya
Summary: The hydrogenation of nitro compounds to amines using a heterogeneous and recyclable catalyst under blue LED irradiation at ambient temperature is described. The protocol involves the use of hydrazine hydrate as a reductant and ethanol as a solvent for green, sustainable, and low-cost production. The synthesis of various (hetero)arylamines and pharmaceutically relevant molecules is demonstrated, with key features including catalyst recyclability, green solvent, ambient temperature, and gram-scale reactions.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Breno de S. Bernardes, Thamires M. da Costa, Leticia de O. J. L. da Silva, Ligia S. da S. Pinto, Victor Facchinetti, Marcus Vinicius Nora de Souza, Thatyana R. A. Vasconcelos
Summary: This review discusses the development of sustainable methodologies for the reduction of aromatic nitro compounds from 2017 to 2020, presenting the reaction conditions, reagents, solvents, and catalysts used, as well as the main advantages of these methods.
Article
Chemistry, Applied
Piotr Cyganowski, Joanna Wolska
Summary: This study presents a new approach for synthesizing aromatic amines using nitroaromatic compounds (NARs) in contaminated wastewaters. The researchers developed anion exchange membranes with gold nanoparticles (AuNPs) to simultaneously reduce and separate the NARs. The nanocomposite membranes formed using tetrahydrofuran (THF) showed better performance in the reduction and separation process.
REACTIVE & FUNCTIONAL POLYMERS
(2022)
Article
Multidisciplinary Sciences
James Burrows, Shogo Kamo, Kazunori Koide
Summary: This article presents a Birch reduction method that is simpler, safer, more efficient, and more environmentally friendly, for converting arenes into 1,4-cyclohexadienes. The method is easy to operate, cost-effective, and applicable to various chemical laboratories, making it a new technology with wide application prospects.
Article
Chemistry, Organic
Chuanling Chen, Chengrong Lu, Bei Zhao
Summary: This study presents a new catalyst for the reaction of HBPin with nitro compounds, resulting in high yields of N-borylamines. The derivatives of N-borylamines were also obtained through a sequential one-pot method. Moreover, kinetic studies of the reaction were conducted.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Nahal Aramesh, Bahram Yadollahi
Summary: The present study developed an impressive method to eliminate toxic nitro aromatic compounds using polyoxometalate-based composites. By integrating transition metal substituted polyoxometalates onto modified protonated graphitic carbon nitride, stable compounds were formed and used for the reduction of toxic compounds. The composite with copper substituted polyoxometalate showed the highest catalytic activity. This environmentally friendly process could be carried out in water at room temperature.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Sedigheh Azadi, Ali Reza Sardarian, Mohsen Esmaeilpour
Summary: Fe3O4@SiO2/Schiff base/Pd(II) is reported as a magnetically recoverable heterogeneous catalyst for the chemoselective reduction of aromatic nitro compounds to the corresponding amines through catalytic transfer hydrogenation (CTH). The experiments demonstrated successful reduction of aromatic nitro compounds with good to excellent yields and short reaction times. This method utilizes a small amount of the magnetic nanocatalyst along with a cheap and safe hydrogen source to selectively produce important amine substances, making it economical, cheap, environmentally friendly, and simple.
MONATSHEFTE FUR CHEMIE
(2021)
Article
Food Science & Technology
Chenxia Zhang, Mengle Li, Weiwei Ma, Yuxiang Ma, Xuede Wang, Huamin Liu
Summary: This study evaluated the effects of different production conditions on the content of heterocyclic aromatic amines (HAAs) in oils and provided strategies for reducing HAAs to ensure the safety of oil products.
FOOD QUALITY AND SAFETY
(2023)
Article
Chemistry, Multidisciplinary
Kyohei Hayashi, Jeremy Griffin, Kaid C. Harper, Yu Kawamata, Phil S. Baran
Summary: This study reveals a simpler method for reduction reactions by altering the waveform of current delivery. The method can be performed in a protic solvent without the need for metal additives or stringent anhydrous conditions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)